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Antimicrobial Agents and Chemotherapy, September 2005, p. 3937-3939, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3937-3939.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

The vanB2 Gene Cluster of the Majority of Vancomycin-Resistant Enterococcus faecium Isolates from Taiwan Is Associated with the pbp5 Gene and Is Carried by Tn5382 Containing a Novel Insertion Sequence

Jang-Jih Lu,* Tein-Yao Chang, Cherng-Lih Perng, and Shih-Yi Lee

Division of Clinical Pathology, Department of Pathology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China

Received 2 February 2005/ Returned for modification 17 April 2005/ Accepted 5 June 2005

Thirty-two vanB2 Enterococcus faecium isolates were found to harbor Tn5382. Twenty-four isolates had a 1,419-bp sequence inserted within the open reading frame (ORF) C of Tn5382. This 1,419-bp sequence contained a 638-bp ORF with a 72% amino acid sequence homology with the transposase gene of IS150. Thirty isolates had the pbp5 gene linked to Tn5382.

* Corresponding author. Mailing address: No. 325, Section 2, Cheng-kung Rd. Neihu, Taipei, Taiwan 114, Republic of China. Phone: 886-2-8792-7227. Fax: 886-2-8792-7226. E-mail: jjl{at}mail.ndmctsgh.edu.tw.

Antimicrobial Agents and Chemotherapy, September 2005, p. 3937-3939, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3937-3939.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Torres, C., Escobar, S., Portillo, A., Torres, L., Rezusta, A., Ruiz-Larrea, F., Revillo, M. J., Aspiroz, C., Zarazaga, M. (2006). Detection of clonally related vanB2-containing Enterococcus faecium strains in two Spanish hospitals.. J Med Microbiol 55: 1237-1243 [Abstract] [Full Text]  


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