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Antimicrobial Agents and Chemotherapy, January 2006, p. 388-390, Vol. 50, No. 1
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.1.388-390.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Bloodstream Infections with Metallo-ß-Lactamase-Producing Pseudomonas aeruginosa: Epidemiology, Microbiology, and Clinical Outcomes

Alexandre R. Marra,1* Carlos Alberto P. Pereira,1 Ana Cristina Gales,1,2 Liana C. Menezes,2 Ruy Guilherme R. Cal,3 José Marconi A. de Souza,3 Michael B. Edmond,4 Cynthia Faro,2 and Sérgio B. Wey1

Division of Infectious Diseases, Universidade Federal de São Paulo, Brasil (UNIFESP-EPM)/Hospital São Paulo,1 Laboratório Alerta, Universidade Federal de São Paulo (UNIFESP-EPM)/Hospital São Paulo,2 Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil,3 Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia4

Received 25 March 2005/ Returned for modification 19 May 2005/ Accepted 6 October 2005

Pseudomonas aeruginosa strains that produce metallo-ß-lactamases (MBLs) are becoming increasingly prevalent. We evaluated the epidemiological and microbiological characteristics of monomicrobial bloodstream infections caused by MBL-producing P. aeruginosa isolates, as well as the clinical outcomes in patients with these infections.

* Corresponding author. Mailing address: Universidade Federal de São Paulo, Escola Paulista de Medicina, Rua Napoleão de Barros, 715 7° andar, CEP 04023-062, São Paulo, SP, Brazil. Phone: 55 11 5576-4094. Fax: 55 11 5576-4094. E-mail: a.marra{at}uol.com.br.

Antimicrobial Agents and Chemotherapy, January 2006, p. 388-390, Vol. 50, No. 1
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.1.388-390.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Tsakris, A., Poulou, A., Kristo, I., Pittaras, T., Spanakis, N., Pournaras, S., Markou, F. (2009). Large Dissemination of VIM-2-Metallo-{beta}-Lactamase-Producing Pseudomonas aeruginosa Strains Causing Health Care-Associated Community-Onset Infections. J. Clin. Microbiol. 47: 3524-3529 [Abstract] [Full Text]  
  • MacGowan, A. P., on behalf of the BSAC Working Parties on Resistanc, (2008). Clinical implications of antimicrobial resistance for therapy. J Antimicrob Chemother 62: ii105-ii114 [Abstract] [Full Text]  
  • Zavascki, A. P., Barth, A. L., Goldani, L. Z. (2008). Nosocomial bloodstream infections due to metallo-{beta}-lactamase-producing Pseudomonas aeruginosa. J Antimicrob Chemother 61: 1183-1185 [Full Text]  
  • Queenan, A. M., Bush, K. (2007). Carbapenemases: the Versatile {beta}-Lactamases. Clin. Microbiol. Rev. 20: 440-458 [Abstract] [Full Text]  


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