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Antimicrobial Agents and Chemotherapy, October 2006, p. 3507-3513, Vol. 50, No. 10
0066-4804/06/$08.00+0     doi:10.1128/AAC.00499-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Comparative In Vitro Susceptibilities of 396 Unusual Anaerobic Strains to Tigecycline and Eight Other Antimicrobial Agents{triangledown}

Ellie J. C. Goldstein,1,2* Diane M. Citron,1 C. Vreni Merriam,1 Yumi A. Warren,1 Kerin L. Tyrrell,1 and Helen T. Fernandez1

R. M. Alden Research Laboratory, Santa Monica, California 90404,1 David Geffen School of Medicine at UCLA, Los Angeles, California 900732

Received 21 April 2006/ Returned for modification 26 July 2006/ Accepted 10 August 2006

Tigecycline was tested against 396 strains of lesser-known anaerobic species encountered in human infections. It was active against all gram-positive strains and 228 of 232 gram-negative anaerobes at ≤1 µg/ml. One strain of Prevotella oralis was nonsusceptible at 8 µg/ml.

* Corresponding author. Mailing address: R. M. Alden Research Laboratory, 2021 Santa Monica Blvd., 740 East, Santa Monica, CA 90404. Phone: (310) 315-1511. Fax: (310) 315-3662. E-mail: ejcgmd{at}aol.com.

{triangledown} Published ahead of print on 28 August 2006.

Antimicrobial Agents and Chemotherapy, October 2006, p. 3507-3513, Vol. 50, No. 10
0066-4804/06/$08.00+0     doi:10.1128/AAC.00499-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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