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Antimicrobial Agents and Chemotherapy, February 2006, p. 785-787, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.785-787.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum ß-Lactamase in Austria

Institute of Hygiene, Medical University of Graz, 8010 Graz, Austria,¹ Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, London NW9 5HT, United Kingdom²

Received 9 August 2005/ Returned for modification 31 August 2005/ Accepted 15 October 2005

Among 149 extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.

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