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Antimicrobial Agents and Chemotherapy, February 2006, p. 785-787, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.785-787.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum ß-Lactamase in Austria

Alexandra Eisner,1* Elizabeth J. Fagan,2 Gebhard Feierl,1 Harald H. Kessler,1 Egon Marth,1 David M. Livermore,2 and Neil Woodford2

Institute of Hygiene, Medical University of Graz, 8010 Graz, Austria,1 Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, London NW9 5HT, United Kingdom2

Received 9 August 2005/ Returned for modification 31 August 2005/ Accepted 15 October 2005

Among 149 extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.

* Corresponding author. Mailing address: Institute of Hygiene, Medical University of Graz, Universitätsplatz 4, A-8010 Graz, Austria. Phone: 43 (316) 380-4383. Fax: 43 (316) 380-9648. E-mail: alexandra.eisner{at}meduni-graz.at.

Antimicrobial Agents and Chemotherapy, February 2006, p. 785-787, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.785-787.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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