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Antimicrobial Agents and Chemotherapy, March 2006, p. 1067-1070, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1067-1070.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Enterococcus gallinarum N04-0414 Harbors a VanD-Type Vancomycin Resistance Operon and Does Not Contain a D-Alanine:D-Alanine 2 (ddl2) Gene

David A. Boyd,1 Mark A. Miller,2 and Michael R. Mulvey1*

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba,1 SMBD-Jewish General Hospital and McGill University, Montreal, Quebec, Canada2

Received 28 September 2005/ Returned for modification 20 October 2005/ Accepted 5 December 2005

Enterococcus gallinarum N04-0414 (MIC for vancomycin, 256 µg/ml) harbored a vanD-type vancomycin resistance operon as well as the intrinsic vanC1 operon. The D-Ala:D-Ala ligase 2 gene (ddl2) was not present in the strain, though it is found downstream of the vanS gene from the vanC operon in E. gallinarum ATCC 49573 and 19 other E. gallinarum strains tested.

* Corresponding author. Mailing address: National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada R3E 3R2. Phone: (204) 789-2133. Fax: (204) 789-5020. E-mail: Michael_mulvey{at}phac-aspc.gc.ca.

Antimicrobial Agents and Chemotherapy, March 2006, p. 1067-1070, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1067-1070.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Depardieu, F., Foucault, M.-L., Bell, J., Dubouix, A., Guibert, M., Lavigne, J.-P., Levast, M., Courvalin, P. (2009). New Combinations of Mutations in VanD-Type Vancomycin-Resistant Enterococcus faecium, Enterococcus faecalis, and Enterococcus avium Strains. Antimicrob. Agents Chemother. 53: 1952-1963 [Abstract] [Full Text]  
  • Domingo, M.-C., Huletsky, A., Giroux, R., Picard, F. J., Bergeron, M. G. (2007). vanD and vanG-Like Gene Clusters in a Ruminococcus Species Isolated from Human Bowel Flora. Antimicrob. Agents Chemother. 51: 4111-4117 [Abstract] [Full Text]  


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