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Antimicrobial Agents and Chemotherapy, March 2006, p. 1089-1091, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1089-1091.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Staphylococcus Efflux msr(A) Gene Characterized in Streptococcus, Enterococcus, Corynebacterium, and Pseudomonas Isolates{dagger}

Kayode K. Ojo,1 Megan J. Striplin,1 Catherine C. Ulep,1 Natasha S. Close,1 Jennifer Zittle,1 Henrique Luis,2 Mario Bernardo,2 Jorge Leitao,2 and Marilyn C. Roberts1*

Department of Pathobiology, University of Washington, Seattle, Washington 98195,1 University of Lisbon, Lisbon, Portugal2

Received 17 August 2005/ Returned for modification 23 November 2005/ Accepted 12 December 2005

The staphylococcal msr(A) gene, coding for a macrolide efflux protein, was identified in three new gram-positive genera and one gram-negative genus. These msr(A) genes shared 99 to 100% identity with each other and the staphylococcal gene. This study demonstrates that the msr(A) gene has a wider host range than previously reported.

* Corresponding author. Mailing address: Department of Pathobiology, Box 357238, University of Washington, Seattle, WA 98195-7238. Phone: (206) 543-8001. Fax: (206) 543-3873. E-mail: marilynr{at}u.washington.edu.

{dagger} Supplemental material for this article may be found at http://aac.asm.org/.

Antimicrobial Agents and Chemotherapy, March 2006, p. 1089-1091, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1089-1091.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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