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Antimicrobial Agents and Chemotherapy, April 2006, p. 1528-1530, Vol. 50, No. 4
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.4.1528-1530.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Microflora Changes with Norfloxacin and Pivmecillinam in Women with Recurrent Urinary Tract Infection

Birgit Stattin Norinder,1* Ragnar Norrby,2 Ann-Chatrin Palmgren,1 Sofia Hollenberg,3 Ulla Eriksson,3 and Carl Erik Nord1

Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden,1 Swedish Institute for Infectious Disease Control, Solna, Sweden,2 Väsby Östra Vårdcentral, Löwenströmska Hospital, Upplands Väsby, Sweden3

Received 26 July 2005/ Returned for modification 21 September 2005/ Accepted 22 January 2006

Similar changes in the periurethral and vaginal microflora were observed in 19 women with recurrent urinary tract infection following treatment with norfloxacin (NOR) or pivmecillinam (PIV). Escherichia coli strains were suppressed by both treatments. Staphylococcus spp. and enterococci colony counts increased following PIV treatment in the periurethral flora but remained stable with NOR.

* Corresponding author. Mailing address: Department of Laboratory Medicine F82, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden. Phone: 46 8 585 878 35. Fax: 46 8 7113918. E-mail: birgitsn{at}cix.co.uk.

Antimicrobial Agents and Chemotherapy, April 2006, p. 1528-1530, Vol. 50, No. 4
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.4.1528-1530.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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