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Antimicrobial Agents and Chemotherapy, August 2006, p. 2872-2874, Vol. 50, No. 8
0066-4804/06/$08.00+0     doi:10.1128/AAC.01647-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

qnr Prevalence in Ceftazidime-Resistant Enterobacteriaceae Isolates from the United States

A. Robicsek,1,{dagger} J. Strahilevitz,1 D. F. Sahm,2 G. A. Jacoby,3 and D. C. Hooper1*

Massachusetts General Hospital, Boston, Massachusetts,1 Focus BioInova, Herndon, Virginia,2 Lahey Clinic, Burlington, Massachusetts3

Received 29 December 2005/ Returned for modification 15 February 2006/ Accepted 27 April 2006

We screened 313 ceftazidime-resistant Enterobacteriaceae isolates obtained in the United States from 1999 to 2004 for all three known qnr genes. A qnr gene was present in 20% of Klebsiella pneumoniae isolates, 31% of Enterobacter sp. isolates, and 4% of Escherichia coli isolates. qnrA and qnrB occurred with equivalent frequencies and, except for qnrB in enterobacters, were stable over time. qnrS was absent.

* Corresponding author. Mailing address: Division of Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114-2696. Phone: (617) 726-3812. Fax: (617) 726-7416. E-mail: dhooper{at}partners.org.

{dagger} Present address: Evanston Northwestern Healthcare, Evanston, Illinois.

Antimicrobial Agents and Chemotherapy, August 2006, p. 2872-2874, Vol. 50, No. 8
0066-4804/06/$08.00+0     doi:10.1128/AAC.01647-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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