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Antimicrobial Agents and Chemotherapy, January 2007, p. 346-349, Vol. 51, No. 1
0066-4804/07/$08.00+0     doi:10.1128/AAC.00614-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Quinolone Resistance in Helicobacter pylori Isolates in Germany{triangledown}

Erik Glocker,1 Hans-Peter Stueger,2 and Manfred Kist1*

Department of Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann-Herder-Str. 11, 79104 Freiburg, Germany,1 Institute of Biostatistics, Austrian Agency for Health and Food Safety, Graz, Austria2

Received 19 May 2006/ Returned for modification 23 June 2006/ Accepted 6 October 2006

We show that quinolone resistance in Helicobacter pylori has reached an alarming level in Germany. Our data suggest that the use of quinolones requires prior antimicrobial susceptibility testing, especially for isolates from patients who have already undergone previous unsuccessful eradication treatments, and also underline the further need for surveillance studies to monitor antibiotic resistance in H. pylori.

* Corresponding author. Mailing address: Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum Freiburg, Hermann-Herder-Straße 11, D-79104 Freiburg, Germany. Phone: 49-761-203-6590. Fax: 49-761-203-6562. E-mail: manfred.kist{at}uniklinik-freiburg.de.

{triangledown} Published ahead of print on 16 October 2006.

Antimicrobial Agents and Chemotherapy, January 2007, p. 346-349, Vol. 51, No. 1
0066-4804/07/$08.00+0     doi:10.1128/AAC.00614-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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