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Antimicrobial Agents and Chemotherapy, April 2007, p. 1553-1555, Vol. 51, No. 4
0066-4804/07/$08.00+0     doi:10.1128/AAC.01405-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing ß-Lactamase{triangledown}

Maria Virginia Villegas,1 Karen Lolans,2,3 Adriana Correa,1 Juan Nicolas Kattan,1 Jaime A. Lopez,4 John P. Quinn,2,3,5* and the Colombian Nosocomial Resistance Study Group

CIDEIM (International Center for Medical Research and Training), Cali, Colombia,1 John Stroger Hospital, Chicago, Illinois,2 Chicago Infectious Disease Research Institute, Chicago, Illinois,3 Hospital Pablo Tobon Uribe, Medellin, Colombia,4 Rush University Medical Center, Chicago, Illinois5

Received 9 November 2006/ Returned for modification 11 December 2006/ Accepted 21 January 2007

In Medellin, Colombia, three Pseudomonas aeruginosa isolates with high-level carbapenem resistance (MIC ≥ 256 µg/ml) and an isolate of Citrobacter freundii with reduced susceptibility to imipenem produced the plasmid-mediated class A carbapenemase KPC-2. This is the first report of a KPC-type ß-lactamase identified outside of the family Enterobacteriaceae.

* Corresponding author. Mailing address: 1900 W. Polk, Rm. 1236, Chicago, IL 60612. Phone: (312) 864-4874. Fax: (312) 864-9522. E-mail: ESBLman{at}yahoo.com

{triangledown} Published ahead of print on 29 January 2007.

Antimicrobial Agents and Chemotherapy, April 2007, p. 1553-1555, Vol. 51, No. 4
0066-4804/07/$08.00+0     doi:10.1128/AAC.01405-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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