This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Papagiannitsis, C. C.
Right arrow Articles by Miriagou, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Papagiannitsis, C. C.
Right arrow Articles by Miriagou, V.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, June 2007, p. 2185-2188, Vol. 51, No. 6
0066-4804/07/$08.00+0     doi:10.1128/AAC.01439-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

SCO-1, a Novel Plasmid-Mediated Class A ß-Lactamase with Carbenicillinase Characteristics from Escherichia coli{triangledown}

C. C. Papagiannitsis,1 A. Loli,1 L. S. Tzouvelekis,2 E. Tzelepi,1 G. Arlet,3 and V. Miriagou1*

Laboratory of Bacteriology, Institut Pasteur Hellenique,1 Department of Microbiology, School of Medicine, University of Athens, Athens, Greece,2 Laboratoire de Bacteriologie, UPRES EA 2392, UFR Saint-Antoine, Universite Paris VI, Paris, France3

Received 17 November 2006/ Returned for modification 9 February 2007/ Accepted 5 March 2007

A novel class A ß-lactamase (SCO-1) encoded by an 80-kb self-transferable plasmid from Escherichia coli is described. The interaction of SCO-1 with ß-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8).

* Corresponding author. Mailing address: Laboratory of Bacteriology, Institut Pasteur Hellenique, Vas. Sofias 127, Athens 11521, Greece. Phone: 30-210-6478810. Fax: 30-210-6423498. E-mail: miriagou{at}mail.pasteur.gr

{triangledown} Published ahead of print on 12 March 2007.

Antimicrobial Agents and Chemotherapy, June 2007, p. 2185-2188, Vol. 51, No. 6
0066-4804/07/$08.00+0     doi:10.1128/AAC.01439-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Papagiannitsis, C. C., Tzouvelekis, L. S., Tzelepi, E., Miriagou, V. (2007). Plasmid-Encoded ACC-4, an Extended-Spectrum Cephalosporinase Variant from Escherichia coli. Antimicrob. Agents Chemother. 51: 3763-3767 [Abstract] [Full Text]  
  • Partridge, S. R., Arlet, G. (2007). Genetic Environment of ISEcp1 and blaACC-1. Antimicrob. Agents Chemother. 51: 2658-2659 [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»