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Antimicrobial Agents and Chemotherapy, February 2008, p. 742-744, Vol. 52, No. 2
0066-4804/08/$08.00+0     doi:10.1128/AAC.00960-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Tetracycline Resistance in Ureaplasma spp. and Mycoplasma hominis: Prevalence in Bordeaux, France, from 1999 to 2002 and Description of Two tet(M)-Positive Isolates of M. hominis Susceptible to Tetracyclines{triangledown}

S. Dégrange, H. Renaudin, A. Charron, C. Bébéar, and C. M. Bébéar*

Laboratoire de Bactériologie EA 3671, Université Victor Segalen Bordeaux 2 and CHU de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France

Received 25 July 2007/ Returned for modification 2 October 2007/ Accepted 5 November 2007

Twenty-four of 128 clinical isolates of Mycoplasma hominis and 6 of 276 clinical isolates of Ureaplasma spp. from Bordeaux, France (1999 to 2002), were resistant to tetracycline and harbored the tet(M) gene. For M. hominis, we also found an increase in tetracycline resistance and two tet(M)-positive isolates that were susceptible to tetracyclines.


* Corresponding author. Mailing address: Laboratoire de Bactériologie EA 3671, Mycoplasma and chlamydiae infections in humans, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. Phone: (33) 5 57 57 16 25. Fax: (33) 5 56 93 29 40. E-mail: cecile.bebear{at}u-bordeaux2.fr

{triangledown} Published ahead of print on 19 November 2007.


Antimicrobial Agents and Chemotherapy, February 2008, p. 742-744, Vol. 52, No. 2
0066-4804/08/$08.00+0     doi:10.1128/AAC.00960-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.




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  • Beeton, M. L., Chalker, V. J., Maxwell, N. C., Kotecha, S., Spiller, O. B. (2009). Concurrent Titration and Determination of Antibiotic Resistance in Ureaplasma Species with Identification of Novel Point Mutations in Genes Associated with Resistance. Antimicrob. Agents Chemother. 53: 2020-2027 [Abstract] [Full Text]  
  • Degrange, S., Renaudin, H., Charron, A., Pereyre, S., Bebear, C., Bebear, C. M. (2008). Reduced susceptibility to tetracyclines is associated in vitro with the presence of 16S rRNA mutations in Mycoplasma hominis and Mycoplasma pneumoniae. J Antimicrob Chemother 61: 1390-1392 [Full Text]