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Antimicrobial Agents and Chemotherapy, March 2008, p. 1140-1143, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.01352-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Plasmid-Borne erm(T) from Invasive, Macrolide-Resistant Streptococcus pyogenes Strains{triangledown}

Robyn L. Woodbury,1 Kathryn A. Klammer,2 Yang Xiong,2 Timothy Bailiff,1 Anita Glennen,2 Joanne M. Bartkus,2 Ruth Lynfield,2 Chris Van Beneden,1 Bernard W. Beall,* for the Active Bacterial Core Surveillance Team

Division of Bacterial Diseases, Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333,1 Minnesota Department of Health, St. Paul, Minnesota 551642

Received 19 October 2007/ Returned for modification 15 November 2007/ Accepted 14 December 2007

Twenty-three isolates of group A streptococci (GAS) recovered from population-based invasive GAS surveillance in the United States were erythromycin resistant, inducibly clindamycin resistant, and lacked known macrolide resistance determinants. These 23 isolates, representing four different clones, contained a broad-host-range plasmid carrying the erm(T) methylase gene, which has not been detected in GAS previously.


* Corresponding author. Mailing address: Division of Bacterial Diseases, Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333. Phone: (404) 639-1237. Fax: (404) 639-4215. E-mail: bbeall{at}cdc.gov

{triangledown} Published ahead of print on 7 January 2008.


Antimicrobial Agents and Chemotherapy, March 2008, p. 1140-1143, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.01352-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.




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