This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Montero, C. I.
Right arrow Articles by Murray, P. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Montero, C. I.
Right arrow Articles by Murray, P. R.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, March 2008, p. 1167-1170, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.00774-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Mechanisms of Resistance to Daptomycin in Enterococcus faecium{triangledown}

Clemente I. Montero,* Frida Stock, and Patrick R. Murray

Microbiology Service, Department of Laboratory Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, U.S. Department of Health and Human Services, 10 Center Drive, MSC 1508, Bethesda, Maryland 20892-1508

Received 15 June 2007/ Returned for modification 15 August 2007/ Accepted 26 December 2007

In this study, we investigated the clonal emergence of daptomycin-resistant Enterococcus faecium strains isolated from a patient with leukocyte adhesion deficiency syndrome. The resistance mechanism in these strains is independent of either equivalent point mutations previously described for Staphylococcus aureus or daptomycin inactivation mechanisms identified in soil bacteria.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Clinical Center Building 10, Room 2C385, Bethesda MD 20892-1508. Phone: (301) 402-2144. Fax: (301) 402-1886. E-mail: monteroc{at}cc.nih.gov

{triangledown} Published ahead of print on 7 January 2008.

Antimicrobial Agents and Chemotherapy, March 2008, p. 1167-1170, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.00774-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Schoen, C., Unzicker, C., Stuhler, G., Elias, J., Einsele, H., Grigoleit, G. U., Abele-Horn, M., Mielke, S. (2009). Life-Threatening Infection Caused by Daptomycin-Resistant Corynebacterium jeikeium in a Neutropenic Patient. J. Clin. Microbiol. 47: 2328-2331 [Abstract] [Full Text]  
  • Hawkey, P. M. (2008). Pre-clinical experience with daptomycin. J Antimicrob Chemother 62: iii7-iii14 [Abstract] [Full Text]  
  • Warren, R. E. (2008). Daptomycin in endocarditis and bacteraemia: a British perspective. J Antimicrob Chemother 62: iii25-iii33 [Abstract] [Full Text]  
  • Livermore, D. M. (2008). Future directions with daptomycin. J Antimicrob Chemother 62: iii41-iii49 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»