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Antimicrobial Agents and Chemotherapy, March 2008, p. 1182-1183, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.01332-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vitro Activity of AR-709 against Streptococcus pneumoniae{triangledown}

W. T. M. Jansen,* A. Verel, J. Verhoef, and D. Milatovic

University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands

Received 16 October 2007/ Returned for modification 15 November 2007/ Accepted 21 December 2007

We investigated the in vitro activity of AR-709, a novel diaminopyrimidine antibiotic currently in development for treatment of community-acquired upper and lower respiratory tract infections, against 151 Streptococcus pneumoniae strains from various European countries. AR-709 showed excellent activity against both drug-susceptible and multidrug-resistant pneumococci.

* Corresponding author. Mailing address: University Medical Center Utrecht, Medical Microbiology Dept., G 04.614, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. Phone: 31-30-2503566. Fax: 31-30-2541770. E-mail: w.t.m.jansen{at}umcutrecht.nl

{triangledown} Published ahead of print on 7 January 2008.

Antimicrobial Agents and Chemotherapy, March 2008, p. 1182-1183, Vol. 52, No. 3
0066-4804/08/$08.00+0     doi:10.1128/AAC.01332-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Smith, K., Ednie, L. M., Appelbaum, P. C., Hawser, S., Lociuro, S. (2008). Antistreptococcal Activity of AR-709 Compared to That of Other Agents. Antimicrob. Agents Chemother. 52: 2279-2282 [Abstract] [Full Text]  


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