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Antimicrobial Agents and Chemotherapy, June 2008, p. 2228-2231, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00176-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vitro Antifungal Susceptibility and Molecular Characterization of Clinical Isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum{triangledown}

Mónica Azor,1 Josepa Gené,1 Josep Cano,1 Deanna A. Sutton,2 Annette W. Fothergill,2 Michael G. Rinaldi,2,3 and Josep Guarro1*

Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Tarragona, Spain,1 Fungus Testing Laboratory, Department of Pathology, The University of Texas Health Science Center,2 Audie L. Murphy Memorial Veterans' Hospital, South Texas Veterans Health Care System, San Antonio, Texas3

Received 7 February 2008/ Returned for modification 6 March 2008/ Accepted 28 March 2008

A microdilution method was used to test 11 antifungal drugs against clinical isolates of Fusarium thapsinum and three different phylogenetic clades of Fusarium verticillioides that were characterized by sequencing a region of the β-tubulin gene. Terbinafine was the most-active drug against both species, followed by posaconazole against F. verticillioides.

* Corresponding author. Mailing address: Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, C/ Sant Llorenç 21, 43201 Reus, Tarragona, Spain. Phone: 34 977 759359. Fax: 34 977 759322. E-mail: josep.guarro{at}urv.cat

{triangledown} Published ahead of print on 7 April 2008.

Antimicrobial Agents and Chemotherapy, June 2008, p. 2228-2231, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00176-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Azor, M., Gene, J., Cano, J., Manikandan, P., Venkatapathy, N., Guarro, J. (2009). Less-Frequent Fusarium Species of Clinical Interest: Correlation between Morphological and Molecular Identification and Antifungal Susceptibility. J. Clin. Microbiol. 47: 1463-1468 [Abstract] [Full Text]  
  • Balajee, S. A., Borman, A. M., Brandt, M. E., Cano, J., Cuenca-Estrella, M., Dannaoui, E., Guarro, J., Haase, G., Kibbler, C. C., Meyer, W., O'Donnell, K., Petti, C. A., Rodriguez-Tudela, J. L., Sutton, D., Velegraki, A., Wickes, B. L. (2009). Sequence-Based Identification of Aspergillus, Fusarium, and Mucorales Species in the Clinical Mycology Laboratory: Where Are We and Where Should We Go from Here?. J. Clin. Microbiol. 47: 877-884 [Full Text]  


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