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Antimicrobial Agents and Chemotherapy, June 2008, p. 2242-2243, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00211-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vitro Activity of Anidulafungin against Candida albicans Biofilms {triangledown}

Melissa J. Jacobson,1 Kerryl E. Piper,1 Gary Nguyen,1 James M. Steckelberg,1 and Robin Patel1,2*

Division of Infectious Diseases, Department of Medicine,1 Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota2

Received 14 February 2008/ Returned for modification 8 March 2008/ Accepted 28 March 2008

We tested the activity of anidulafungin against 30 Candida albicans isolates. The planktonic MICs for 50 and 90% of the isolates tested (MIC50 and MIC90) were ≤0.03 and 0.125 µg/ml, respectively (MIC range, ≤0.03 to 2 µg/ml). The sessile MIC50 and MIC90 were ≤0.03 and ≤0.03 µg/ml, respectively (MIC range, ≤0.03 to >16 µg/ml).

* Corresponding author. Mailing address: Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street S.W., Rochester, MN 55905. Phone: (507) 538-0579. Fax: (507) 284-4272. E-mail: patel.robin{at}mayo.edu

{triangledown} Published ahead of print on 7 April 2008.

Antimicrobial Agents and Chemotherapy, June 2008, p. 2242-2243, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00211-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Pai, M. P. (2009). Antifungal Combinations against Simulated Candida albicans Endocardial Vegetations. Antimicrob. Agents Chemother. 53: 2629-2631 [Abstract] [Full Text]  
  • Jacobson, M. J., Steckelberg, K. E., Piper, K. E., Steckelberg, J. M., Patel, R. (2009). In Vitro Activity of Micafungin against Planktonic and Sessile Candida albicans Isolates. Antimicrob. Agents Chemother. 53: 2638-2639 [Abstract] [Full Text]  


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