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Antimicrobial Agents and Chemotherapy, June 2008, p. 2270-2272, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00037-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Genetic Environment of 16S rRNA Methylase Gene rmtD{triangledown}

Yohei Doi,1* Jennifer M. Adams-Haduch,1 and David L. Paterson1,2

Division of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania,1 University of Queensland, Royal Brisbane and Women's Hospital, Brisbane, Australia2

Received 9 January 2008/ Returned for modification 24 February 2008/ Accepted 24 March 2008

The genetic environment of the 16S rRNA methylase gene rmtD was investigated. rmtD was flanked by a novel ISCR motif located downstream of class I integron In163 in the original Pseudomonas aeruginosa strain. rmtD found in Klebsiella pneumoniae appeared to have been mobilized from P. aeruginosa by an IS26-mediated event.

* Corresponding author. Mailing address: Division of Infectious Diseases, University of Pittsburgh Medical Center, Falk Medical Building Suite 3A, 3601 Fifth Avenue, Pittsburgh, PA 15213. Phone: (412) 648-6401. Fax: (412) 648-6399. E-mail: doiy{at}dom.pitt.edu

{triangledown} Published ahead of print on 7 April 2008.

Antimicrobial Agents and Chemotherapy, June 2008, p. 2270-2272, Vol. 52, No. 6
0066-4804/08/$08.00+0     doi:10.1128/AAC.00037-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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