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Antimicrobial Agents and Chemotherapy, August 2008, p. 2943-2946, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.00679-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Metallo-β-Lactamase Gene blaIMP-15 in a Class 1 Integron, In95, from Pseudomonas aeruginosa Clinical Isolates from a Hospital in Mexico{triangledown}

U. Garza-Ramos,1 R. Morfin-Otero,2 H. S. Sader,3 R. N. Jones,3 E. Hernández,1 E. Rodriguez-Noriega,2 A. Sanchez,1 B. Carrillo,1 S. Esparza-Ahumada,2 and J. Silva-Sanchez1*

Instituto Nacional de Salud Pública, Cuernavaca, Morelos,1 Instituto de Patología Infecciosa y Experimental, Centro Universitario Ciencias de la Salud, Universidad de Guadalajara, and Hospital Civil de Guadalajara, Jalisco, Mexico,2 JMI Laboratories, North Liberty, Iowa3

Received 23 May 2007/ Returned for modification 22 July 2007/ Accepted 11 May 2008

During 2003, 40 carbapenem-resistant Pseudomonas aeruginosa clinical isolates collected in a Mexican tertiary-care hospital were screened for metallo-β-lactamase production. Thirteen isolates produced IMP-15, and 12 had a single pulsed-field gel electrophoresis pattern. The blaIMP-15 gene cassette was inserted in a plasmid-borne integron with a unique array of gene cassettes and was named In95.

* Corresponding author. Mailing address: Instituto Nacional de Salud Pública, Av. Universidad # 655, Col. Sta. Ma. Ahuacatitlan, Cuernavaca 62100, Mor., Mexico. Phone: (52) 777 329-3021. Fax: (52) 777 317-5485. E-mail: jsilva{at}correo.insp.mx

{triangledown} Published ahead of print on 19 May 2008.

Antimicrobial Agents and Chemotherapy, August 2008, p. 2943-2946, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.00679-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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