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Antimicrobial Agents and Chemotherapy, August 2008, p. 2984-2987, Vol. 52, No. 8
0066-4804/08/$08.00+0 doi:10.1128/AAC.01634-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
blaIMP-4 in Different Genetic Contexts in Enterobacteriaceae Isolates from Australia
Björn A. Espedido,
Sally R. Partridge, and
Jonathan R. Iredell*
Centre for Infectious Diseases & Microbiology, University of Sydney, Westmead Hospital, Westmead, New South Wales 2145, Australia
Received 20 December 2007/
Returned for modification 19 February 2008/
Accepted 8 May 2008
The IMP-4 metallo-β-lactamase, originally recognized in Acinetobacter spp. from Hong Kong, more recently appeared simultaneously in isolates of the family Enterobacteriaceae from Sydney and Melbourne, Australia. The blaIMP-4-qacG2-aacA4-catB3 cassette array was found in isolates from both cities, but in different wider genetic contexts and on different plasmids, suggesting movement of this array by homologous recombination.
* Corresponding author. Mailing address: CIDM, Level 3 ICPMR Building, Westmead Hospital, Westmead, NSW 2145, Australia. Phone: 612-9845-6255. Fax: 612-9891-5317. E-mail:
jon.iredell{at}swahs.health.nsw.gov.au
Published ahead of print on 19 May 2008.
Antimicrobial Agents and Chemotherapy, August 2008, p. 2984-2987, Vol. 52, No. 8
0066-4804/08/$08.00+0 doi:10.1128/AAC.01634-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.
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