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Antimicrobial Agents and Chemotherapy, March 2009, p. 1242-1244, Vol. 53, No. 3
0066-4804/09/$08.00+0     doi:10.1128/AAC.01368-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

A 10-Year Survey of Antifungal Susceptibility of Candidemia Isolates from Intensive Care Unit Patients in Greece{triangledown}

George Dimopoulos,1,2,{dagger} Aristea Velegraki,3,{dagger}* and Matthew E. Falagas2,4

Department of Critical Care, University Hospital Attikon, Medical School, National and Kapodistrian Univeristy of Athens, Athens, Greece,1 Alfa Institute of Biomedical Sciences, Athens, Greece,2 Mycology Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece,3 Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts4

Received 11 October 2008/ Returned for modification 15 November 2008/ Accepted 18 December 2008

This study retrospectively reviews the susceptibility of 135 baseline ICU candidemia isolates (from 1997 to 2007) to nine antifungals as determined by the AFST-EUCAST microdilution method and identifies the most frequent causative agents of confirmed point-source candidemia outbreaks in local intensive care units. A minority of common and rare Candida species displayed decreased susceptibility to all antifungals.

* Corresponding author. Mailing address: Mikras Asias 75, Goudi, Athens 115 27-GR. Phone: 30-210-746 2146. Fax: 30-210-746 2147. E-mail: aveleg{at}med.uoa.gr

{triangledown} Published ahead of print on 29 December 2008.

{dagger} These authors contributed equally and share first authorship.

Antimicrobial Agents and Chemotherapy, March 2009, p. 1242-1244, Vol. 53, No. 3
0066-4804/09/$08.00+0     doi:10.1128/AAC.01368-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Diekema, D. J., Messer, S. A., Boyken, L. B., Hollis, R. J., Kroeger, J., Tendolkar, S., Pfaller, M. A. (2009). In Vitro Activity of Seven Systemically Active Antifungal Agents against a Large Global Collection of Rare Candida Species as Determined by CLSI Broth Microdilution Methods. J. Clin. Microbiol. 47: 3170-3177 [Abstract] [Full Text]  


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