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Antimicrobial Agents and Chemotherapy, June 2009, p. 2663-2666, Vol. 53, No. 6
0066-4804/09/$08.00+0     doi:10.1128/AAC.00046-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Antibiotic Susceptibility of Waddlia chondrophila in Acanthamoeba castellanii Amoebae{triangledown}

Geneviève Goy and Gilbert Greub*

Center for Research on Intracellular Bacteria (CRIB), Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland

Received 13 January 2009/ Returned for modification 9 March 2009/ Accepted 22 March 2009

Waddlia chondrophila is an emerging cause of miscarriage in bovines and humans. Given the strict intracellular growth of this Chlamydia-like organism, its antibiotic susceptibility was tested by amoebal coculture, cell culture, and real-time PCR. W. chondrophila was susceptible to doxycycline and azithromycin but resistant to β-lactams and fluoroquinolones.

* Corresponding author. Mailing address: Center for Research on Intracellular Bacteria, Institute of Microbiology, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland. Phone: 41 21 314 49 79. Fax: 41 21 314 40 60. E-mail: gilbert.greub{at}chuv.ch

{triangledown} Published ahead of print on 30 March 2009.

Antimicrobial Agents and Chemotherapy, June 2009, p. 2663-2666, Vol. 53, No. 6
0066-4804/09/$08.00+0     doi:10.1128/AAC.00046-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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