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Antimicrobial Agents and Chemotherapy, July 2009, p. 3115-3117, Vol. 53, No. 7
0066-4804/09/$08.00+0     doi:10.1128/AAC.00893-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

In Vitro Activity of Doripenem against Burkholderia pseudomallei{triangledown}

Visanu Thamlikitkul* and Suwanna Trakulsomboon

Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand

Received 7 July 2008/ Returned for modification 2 September 2008/ Accepted 19 November 2008

The MIC50 and MIC90 values of doripenem, determined by Etest, for 110 isolates of Burkholderia pseudomallei were 0.5 and 0.75 µg/ml, respectively. There were significant correlations between MICs determined by Etest and MICs determined by agar dilution, MICs determined by Etest and inhibition zone size, and MICs determined by agar dilution and inhibition zone size.


* Corresponding author. Mailing address: Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. Phone and fax: 662-412-5994. E-mail: sivth{at}mahidol.ac.th

{triangledown} Published ahead of print on 13 April 2009.


Antimicrobial Agents and Chemotherapy, July 2009, p. 3115-3117, Vol. 53, No. 7
0066-4804/09/$08.00+0     doi:10.1128/AAC.00893-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.