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Antimicrobial Agents and Chemotherapy, July 2009, p. 3135-3137, Vol. 53, No. 7
0066-4804/09/$08.00+0     doi:10.1128/AAC.00139-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Carriage of CTX-M-15-Producing Escherichia coli Isolates among Children Living in a Remote Village in Senegal{triangledown}

Etienne Ruppé,1,{dagger}* Paul-Louis Woerther,1,{dagger} Abdoulaye Diop,2,3 Anne-Marie Sene,2,3 Annaelle Da Costa,4 Guillaume Arlet,4 Antoine Andremont,1 and Bernard Rouveix3,5

EA3964 University Paris-Diderot Medical School and Associated National Reference Center for Antibiotic Resistance in Commensal Flora, Hôpital Bichat-Claude Bernard, AP-HP, Paris, France,1 Maison de Santé Pierre Fabre, Wassadou, Senegal,2 Association Le Kinkeliba, Paris, France,3 Pierre et Marie Curie-Paris University Medical School, Bacteriology Department, EA 2392, Paris, France,4 Clinical Pharmacology Department, Hôpital Cochin, AP-HP, Paris, France5

Received 30 January 2009/ Returned for modification 15 March 2009/ Accepted 5 April 2009

Two out of 20 children with no known antibiotic exposure, living in a very remote Senegalese village, were found to be fecal carriers of a multiresistant Escherichia coli clone that produced CTX-M-15. This highlights the current massive spread of extended-spectrum β-lactamases, even in isolated communities.


* Corresponding author. Mailing address: Laboratoire de Bactériologie, Hôpital Bichat-Claude Bernard, 46 Rue Henri Huchard, 75018 Paris, France. Phone: 33(0)140258500. Fax: 33(0)140258581. E-mail: etienne.ruppe{at}bch.aphp.fr

{triangledown} Published ahead of print on 13 April 2009.

{dagger} E.R. and P.-L.W. contributed equally to the present study.


Antimicrobial Agents and Chemotherapy, July 2009, p. 3135-3137, Vol. 53, No. 7
0066-4804/09/$08.00+0     doi:10.1128/AAC.00139-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.




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