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Antimicrob. Agents Chemother. doi:10.1128/AAC.00256-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp.; 1990-2005

Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University, Jerusalem, 91120; Department of Medicine, Evanston Northwestern Healthcare, 2650 Ridge Ave, Evanston IL, 60201

^* To whom correspondence should be addressed. Email: jstrahilevitz{at}hadassah.org.il.

	Abstract

Clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 through 2005 at a tertiary care center were studied for qnr genes. Isolates bearing these genes emerged in the mid-1990s, coinciding with the time of rapid increase in fluoroquinolone resistance. 60% of these isolates were ciprofloxacin susceptible by CLSI breakpoints.

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