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Antimicrob. Agents Chemother. doi:10.1128/AAC.00315-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

gyrA and parC mutations and associated quinolone resistance in Vibrio anguillarum serotype O2b isolated from Norwegian farmed Atlantic cod (Gadus morhua)

National Veterinary Institute, Oslo, Norway; North West Fish Health, Gurskøy, Norway

^* To whom correspondence should be addressed. Email: duncan.colquhoun{at}vetinst.no.

	Abstract

MIC testing of Vibrio anguillarum recovered from diseased farmed Atlantic cod, revealed oxolinic acid MICs of 0.001, 0.06 and 16µg ml^-1. Single gyrA Ser- Ile substitutions were identified at position 83 of intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.