AAC Accepts, published online ahead of print on 7 July 2008

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Antimicrob. Agents Chemother. doi:10.1128/AAC.00445-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Identification of a novel mutation in 23S rRNA, which confers low-level resistance to clarithromycin in Helicobacter pylori

Emiko Rimbara, Norihisa Noguchi^*, Takashi Kawai, and Masanori Sasatsu

Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan; Endoscopy Center, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan

^* To whom correspondence should be addressed. Email: noguchin{at}ps.toyaku.ac.jp.

In many countries, the occurrence of clarithromycin-resistant Helicobacter pylori has become increasingly common. ...

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