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AAC Accepts, published online ahead of print on 28 August 2006
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Antimicrob. Agents Chemother. doi:10.1128/AAC.00569-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Complete DNA Sequence, Comparative Genomics, and Prevalence of an IncHI2 Plasmid Occurring among Extraintestinal Pathogenic Escherichia coli

Timothy J. Johnson, Yvonne M. Wannemeuhler, Jennifer A. Scaccianoce, Sara J. Johnson, and Lisa K. Nolan*

Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, 1802 Elwood Drive, VMRI #2, Iowa State University, Ames, IA 50011

* To whom correspondence should be addressed. Email: lknolan{at}iastate.edu.


   Abstract

We have sequenced a large plasmid occurring among avian pathogenic Escherichia coli. This plasmid, pAPEC-O1-R, is a 241,387-bp IncHI2 plasmid which is co-transmissible via bacterial conjugation with a ColBM virulence plasmid, encodes resistance to eight antimicrobial agents, and appears to occur at low rates among extraintestinal E. coli.




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