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Antimicrob. Agents Chemother. doi:10.1128/AAC.00619-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Antibiotic Resistance and SNP Cluster Grouping Type In a Multi-national Sample of M. tuberculosis Resistant Isolates

Department of Preventive Medicine and Community Health and Department of Medicine, New Jersey Medical School - UMDNJ

	Abstract

A single nucleotide polymorphism-based cluster grouping (SCG) classification system for Mycobacterium tuberculosis is used to examine antibiotic resistance type and resistance mutations in relationship to specific evolutionary lineages. Drug resistance and resistance mutations were seen across all SCG. SCG2 had higher proportions of katG315 mutations and resistance to four drugs.

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