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Antimicrob. Agents Chemother. doi:10.1128/AAC.00779-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Increased Macrolide Resistance of Mycoplasma pneumoniae in Pediatric Patients with Community-acquired Pneumonia

Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan; National Hospital Organization Tokyo Medical Center, Tokyo, Japan; Tohoku Rosai Hospital, Miyagi, Japan; Laboratory of Infectious Diseases, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan

^* To whom correspondence should be addressed. Email: ubukatak{at}lisci.kitasato-u.ac.jp.

	Abstract

Among 380 Mycoplasma pneumoniae isolates from 3,678 pediatric patients with community-acquired pneumonia, 50 macrolide-resistant strains had an A2063G transition in domain V of the 23S rRNA while 5 had an A2064G transition. These resistant strains increased rapidly from April 2002 to December 2006.