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Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Chemistry and The Malaria Research Institute, Johns Hopkins University, Baltimore, MD
* To whom correspondence should be addressed. Email:
lbrando{at}jhmi.edu,
Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is medically important and distributed worldwide. Currently available medications are limited in terms of efficacy and side effects. We synthesized novel, non-acetal, hydrolytically stable derivatives of artemisinin and showed that they inhibit the replication of Toxoplasma gondii in cell culture.
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.
In Vitro Inhibition of Toxoplasma gondii by Four New Derivatives of Artemisinin
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