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Antimicrob. Agents Chemother. doi:10.1128/AAC.00856-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms

Laboratory of Infectious Diseases, 3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece; 1^st Department of Microbiology, Aristotle University, University Campus, 54124 Thessaloniki, Greece; 1^st Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece

^* To whom correspondence should be addressed. Email: roilides{at}med.auth.gr.

	Abstract

The activities of voriconazole, posaconazole, caspofungin and anidulafungin against Candida albicans and Candida parapsilosis biofilms were evaluated. In contrast to planktonic cells, biofilms of the two species had high MICs for voriconazole and posaconazole (256 and >64 mg/l respectively), but relatively low for echinocandins (1 and 2 mg/l, respectively).

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• Jacobson, M. J., Piper, K. E., Nguyen, G., Steckelberg, J. M., Patel, R. (2008). In Vitro Activity of Anidulafungin against Candida albicans Biofilms. Antimicrob. Agents Chemother. 52: 2242-2243 [Abstract] [Full Text]