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Antimicrob. Agents Chemother. doi:10.1128/AAC.01139-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Activity of daptomycin against Listeria monocytogenes isolates from cerebrospinal fluid

Netherlands Reference Laboratory for Bacterial Meningitis, Department of Medical Microbiology, and Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands

^* To whom correspondence should be addressed. Email: L.Spanjaard{at}amc.uva.nl.

	Abstract

We tested the susceptibility to daptomycin of 76 Listeria monocytogenes isolates from cerebrospinal fluid with broth dilution and Etest. MIC range and MIC90 were 1.0 - 8.0 and 4.0 mg/L (dilution), and 1.0 - 4.0 and 4.0 mg/L (Etest). Presently, daptomycin cannot be recommended for treatment of L. monocytogenes meningitis.