AAC -- Table of Contents (June 1 1990, 34 [6])

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Contents: June 1990, Volume 34, Issue 6

Research Article

Errata

Other Issues

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Table of Contents

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Research Article:

Molecular biology of penicillin and cephalosporin biosynthesis.
S W Queener
Antimicrob. Agents Chemother. June 1990 34: 943-948;
[PDF] [Reprints and Permissions]

Intracellular activity of tosufloxacin (T-3262) against Salmonella enteritidis and ability to penetrate into tissue culture cells of human origin.
T Noumi, N Nishida, S Minami, Y Watanabe, and T Yasuda
Antimicrob. Agents Chemother. June 1990 34: 949-953;
[Abstract] [PDF] [Reprints and Permissions]

Open trial of cefepime (BMY 28142) for infections in hospitalized patients.
S Oster, H Edelstein, K Cassano, and R McCabe
Antimicrob. Agents Chemother. June 1990 34: 954-957;
[Abstract] [PDF] [Reprints and Permissions]

Penetration of ampicillin and sulbactam in the lower airways during respiratory infections.
Y J Valcke, M T Rosseel, R A Pauwels, M G Bogaert, and M E Van der Straeten
Antimicrob. Agents Chemother. June 1990 34: 958-962;
[Abstract] [PDF] [Reprints and Permissions]

Pathogenicity for humans of human rhinovirus type 2 mutants resistant to or dependent on chalcone Ro 09-0410.
S R Yasin, W al-Nakib, and D A Tyrrell
Antimicrob. Agents Chemother. June 1990 34: 963-966;
[Abstract] [PDF] [Reprints and Permissions]

Liposome-encapsulated-gentamicin therapy of Mycobacterium avium complex infection in beige mice.
S P Klemens, M H Cynamon, C E Swenson, and R S Ginsberg
Antimicrob. Agents Chemother. June 1990 34: 967-970;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activity of tosufloxacin (A-61827; T-3262) against selected genital pathogens.
J Segreti, D J Hirsch, A A Harris, K S Kapell, H Orbach, and H A Kessler
Antimicrob. Agents Chemother. June 1990 34: 971-973;
[Abstract] [PDF] [Reprints and Permissions]

Multiple-dose pharmacokinetics and safety of oral amifloxacin in healthy volunteers.
J A Cook, M H Silverman, D J Schelling, D E Nix, J J Schentag, R R Brown, and R M Stroshane
Antimicrob. Agents Chemother. June 1990 34: 974-979;
[Abstract] [PDF] [Reprints and Permissions]

In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent.
T Tanio, K Ichise, T Nakajima, and T Okuda
Antimicrob. Agents Chemother. June 1990 34: 980-984;
[Abstract] [PDF] [Reprints and Permissions]

High-level chromosomal gentamicin resistance in Streptococcus agalactiae (group B).
A Buu-Hoï, C Le Bouguenec, and T Horaud
Antimicrob. Agents Chemother. June 1990 34: 985-988;
[Abstract] [PDF] [Reprints and Permissions]

In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property.
C Marcireau, M Guilloton, and F Karst
Antimicrob. Agents Chemother. June 1990 34: 989-993;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activity of LJC10,627, a new carbapenem antibiotic with high stability to dehydropeptidase I.
K Ubukata, M Hikida, M Yoshida, K Nishiki, Y Furukawa, K Tashiro, M Konno, and S Mitsuhashi
Antimicrob. Agents Chemother. June 1990 34: 994-1000;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of FCE 22891, a new oral penem.
A Saathoff, H Lode, B Hampel, K M Deppermann, K Borner, and P Koeppe
Antimicrob. Agents Chemother. June 1990 34: 1001-1006;
[Abstract] [PDF] [Reprints and Permissions]

Crossover assessment of serum bactericidal activity and pharmacokinetics of five broad-spectrum cephalosporins in the elderly.
R G Deeter, M P Weinstein, K A Swanson, J S Gross, and L C Bailey
Antimicrob. Agents Chemother. June 1990 34: 1007-1013;
[Abstract] [PDF] [Reprints and Permissions]

Comparative efficacies of ciprofloxacin, pefloxacin, and vancomycin in combination with rifampin in a rat model of methicillin-resistant Staphylococcus aureus chronic osteomyelitis.
R Dworkin, G Modin, S Kunz, R Rich, O Zak, and M Sande
Antimicrob. Agents Chemother. June 1990 34: 1014-1016;
[Abstract] [PDF] [Reprints and Permissions]

Concentrations of oral lomefloxacin in serum and bronchial mucosa.
D R Baldwin, D Honeybourne, J M Andrews, J P Ashby, and R Wise
Antimicrob. Agents Chemother. June 1990 34: 1017-1019;
[Abstract] [PDF] [Reprints and Permissions]

Role of sodium in protection by extended-spectrum penicillins against tobramycin-induced nephrotoxicity.
R Sabra and R A Branch
Antimicrob. Agents Chemother. June 1990 34: 1020-1025;
[Abstract] [PDF] [Reprints and Permissions]

Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia.
S K Jones, J E Hall, M A Allen, S D Morrison, K A Ohemeng, V V Reddy, J D Geratz, and R R Tidwell
Antimicrob. Agents Chemother. June 1990 34: 1026-1030;
[Abstract] [PDF] [Reprints and Permissions]

Effect of renal function on the bioavailability of ciprofloxacin.
K I Plaisance, G L Drusano, A Forrest, M R Weir, and H C Standiford
Antimicrob. Agents Chemother. June 1990 34: 1031-1034;
[Abstract] [PDF] [Reprints and Permissions]

Quantification of antibiotic drug potency by a two-compartment radioassay of bacterial growth.
V Boonkitticharoen, J C Ehrhardt, and P T Kirchner
Antimicrob. Agents Chemother. June 1990 34: 1035-1040;
[Abstract] [PDF] [Reprints and Permissions]

Randomized comparative study of cefixime versus cephalexin in acute bacterial exacerbations of chronic bronchitis.
A Verghese, D Roberson, J H Kalbfleisch, and F Sarubbi
Antimicrob. Agents Chemother. June 1990 34: 1041-1044;
[Abstract] [PDF] [Reprints and Permissions]

Effects of aztreonam on fecal flora and on vitamin K metabolism.
H Sakata, H Kakehashi, K Fujita, and H Yoshioka
Antimicrob. Agents Chemother. June 1990 34: 1045-1047;
[Abstract] [PDF] [Reprints and Permissions]

Investigation of potential interaction of ciprofloxacin with cyclosporine in bone marrow transplant recipients.
H U Krüger, U Schuler, B Proksch, M Göbel, and G Ehninger
Antimicrob. Agents Chemother. June 1990 34: 1048-1052;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics and tissue penetration of ceftibuten.
R Wise, K Nye, P O'Neill, M Wostenholme, and J M Andrews
Antimicrob. Agents Chemother. June 1990 34: 1053-1055;
[Abstract] [PDF] [Reprints and Permissions]

Intracellular accumulation of azithromycin by cultured human fibroblasts.
R P Gladue and M E Snider
Antimicrob. Agents Chemother. June 1990 34: 1056-1060;
[Abstract] [PDF] [Reprints and Permissions]

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1.
R F Schinazi, J P Sommadossi, V Saalmann, D L Cannon, M Y Xie, G C Hart, G A Smith, and E F Hahn
Antimicrob. Agents Chemother. June 1990 34: 1061-1067;
[Abstract] [PDF] [Reprints and Permissions]

Chemoprophylactic efficacy against experimental endocarditis caused by beta-lactamase-producing, aminoglycoside-resistant enterococci is associated with prolonged serum inhibitory activity.
A S Bayer and J Tu
Antimicrob. Agents Chemother. June 1990 34: 1068-1074;
[Abstract] [PDF] [Reprints and Permissions]

Inhibition of Pneumocystis carinii dihydropteroate synthetase by sulfa drugs.
S Merali, Y Zhang, D Sloan, and S Meshnick
Antimicrob. Agents Chemother. June 1990 34: 1075-1078;
[Abstract] [PDF] [Reprints and Permissions]

Ampicillin killing curve patterns for ampicillin-susceptible nontypeable Haemophilus influenzae strains by the agar dilution plate count method.
B F Woolfrey and M A Enright
Antimicrob. Agents Chemother. June 1990 34: 1079-1087;
[Abstract] [PDF] [Reprints and Permissions]

Mechanism of action of lomefloxacin.
L J Piddock, M C Hall, and R Wise
Antimicrob. Agents Chemother. June 1990 34: 1088-1093;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of cefpodoxime in plasma and skin blister fluid following oral dosing of cefpodoxime proxetil.
M T Borin, G S Hughes, C R Spillers, and R K Patel
Antimicrob. Agents Chemother. June 1990 34: 1094-1099;
[Abstract] [PDF] [Reprints and Permissions]

Efficacy, toxicity, and pharmacokinetics of pentoxifylline and its analogs in experimental Staphylococcus aureus infections.
E G Maderazo, S Breaux, C L Woronick, and P J Krause
Antimicrob. Agents Chemother. June 1990 34: 1100-1106;
[Abstract] [PDF] [Reprints and Permissions]

Antibacterial activity of lomefloxacin in a pharmacokinetic in vitro model.
C Rustige and B Wiedemann
Antimicrob. Agents Chemother. June 1990 34: 1107-1111;
[Abstract] [PDF] [Reprints and Permissions]

Inhibitory effects of atropine, protamine, and their combination on hepatitis A virus replication in PLC/PRF/5 cells.
E Biziagos, J M Crance, J Passagot, and R Deloince
Antimicrob. Agents Chemother. June 1990 34: 1112-1117;
[Abstract] [PDF] [Reprints and Permissions]

Safety, tolerance, and pharmacokinetic evaluation of cefepime after administration of single intravenous doses.
R H Barbhaiya, S T Forgue, C R Gleason, C A Knupp, K A Pittman, D J Weidler, and R R Martin
Antimicrob. Agents Chemother. June 1990 34: 1118-1122;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activity of AT-4140 against quinolone- and methicillin-resistant Staphylococcus aureus.
T Kojima, M Inoue, and S Mitsuhashi
Antimicrob. Agents Chemother. June 1990 34: 1123-1127;
[Abstract] [PDF] [Reprints and Permissions]

Assessment of cefazolin and cefuroxime tissue penetration by using a continuous intravenous infusion.
J E Connors, J T DiPiro, R G Hayter, K D Hooker, J A Stanfield, and T R Young
Antimicrob. Agents Chemother. June 1990 34: 1128-1131;
[Abstract] [PDF] [Reprints and Permissions]

Therapeutic effect of the triazole Bay R 3783 in mouse models of coccidioidomycosis, blastomycosis, and histoplasmosis.
D Pappagianis, B L Zimmer, G Theodoropoulos, M Plempel, and R F Hector
Antimicrob. Agents Chemother. June 1990 34: 1132-1138;
[Abstract] [PDF] [Reprints and Permissions]

Interactions of ceftazidime and tobramycin in patients with normal and impaired renal function.
G R Aronoff, R A Brier, R S Sloan, and M E Brier
Antimicrob. Agents Chemother. June 1990 34: 1139-1142;
[Abstract] [PDF] [Reprints and Permissions]

Oral temafloxacin versus vancomycin for therapy of experimental endocarditis caused by methicillin-resistant Staphylococcus aureus.
M T Hessen, P G Pitsakis, and D Kaye
Antimicrob. Agents Chemother. June 1990 34: 1143-1145;
[Abstract] [PDF] [Reprints and Permissions]

Apparent biliary pseudolithiasis during ceftriaxone therapy.
K L Heim-Duthoy, E M Caperton, R Pollock, G R Matzke, D Enthoven, and P K Peterson
Antimicrob. Agents Chemother. June 1990 34: 1146-1149;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetic analysis of cloxacillin loss in children undergoing major surgery with massive bleeding.
M Levy, P Egersegi, A Strong, A Tessoro, M Spino, R Bannatyne, D Fear, J C Posnick, and G Koren
Antimicrob. Agents Chemother. June 1990 34: 1150-1153;
[Abstract] [PDF] [Reprints and Permissions]

Comparative in vitro activity of WIN 57273, a new fluoroquinolone antimicrobial agent.
G M Eliopoulos, K Klimm, L B Rice, M J Ferraro, and R C Moellering, Jr
Antimicrob. Agents Chemother. June 1990 34: 1154-1159;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of cephem antibiotics in exudate of pelvic retroperitoneal space after radical hysterectomy and pelvic lymphadenectomy.
K Ito, M Hayasaki, and T Tamaya
Antimicrob. Agents Chemother. June 1990 34: 1160-1164;
[Abstract] [PDF] [Reprints and Permissions]

Application of a Bayesian method to monitor and adjust vancomycin dosage regimens.
A K Hurst, M A Yoshinaga, G H Mitani, K A Foo, R W Jelliffe, and E C Harrison
Antimicrob. Agents Chemother. June 1990 34: 1165-1171;
[Abstract] [PDF] [Reprints and Permissions]

Clinical pharmacology of imipenem and cilastatin in premature infants during the first week of life.
M D Reed, R M Kliegman, T S Yamashita, C M Myers, and J L Blumer
Antimicrob. Agents Chemother. June 1990 34: 1172-1177;
[Abstract] [PDF] [Reprints and Permissions]

Nucleoside metabolism in herpes simplex virus-infected cells following treatment with interferon and acyclovir, a possible mechanism of synergistic antiviral activity.
W J O'Brien, E C Coe, and J L Taylor
Antimicrob. Agents Chemother. June 1990 34: 1178-1182;
[Abstract] [PDF] [Reprints and Permissions]

Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.
C J Bacchi, H C Nathan, T Livingston, G Valladares, M Saric, P D Sayer, A R Njogu, and A B Clarkson, Jr
Antimicrob. Agents Chemother. June 1990 34: 1183-1188;
[Abstract] [PDF] [Reprints and Permissions]

Uptake of antibiotics by human polymorphonuclear leukocyte cytoplasts.
W L Hand and N L King-Thompson
Antimicrob. Agents Chemother. June 1990 34: 1189-1193;
[Abstract] [PDF] [Reprints and Permissions]

Randomized, double-blind comparison of the efficacies, costs, and vaginal flora alterations with single-dose ceftriaxone and multidose cefazolin prophylaxis in vaginal hysterectomy.
H G Stiver, B O Binns, R C Brunham, N Cheng, D M Dean, A M Goldring, J B Walker, E Tan, and J McLeod
Antimicrob. Agents Chemother. June 1990 34: 1194-1197;
[Abstract] [PDF] [Reprints and Permissions]

Phase I study of multiple-dose cefprozil and comparison with cefaclor.
R H Barbhaiya, U A Shukla, C R Gleason, W C Shyu, R B Wilber, R R Martin, and K A Pittman
Antimicrob. Agents Chemother. June 1990 34: 1198-1203;
[Abstract] [PDF] [Reprints and Permissions]

Comparison of cefprozil and cefaclor pharmacokinetics and tissue penetration.
R H Barbhaiya, U A Shukla, C R Gleason, W C Shyu, R B Wilber, and K A Pittman
Antimicrob. Agents Chemother. June 1990 34: 1204-1209;
[Abstract] [PDF] [Reprints and Permissions]

Comparison of the effects of food on the pharmacokinetics of cefprozil and cefaclor.
R H Barbhaiya, U A Shukla, C R Gleason, W C Shyu, and K A Pittman
Antimicrob. Agents Chemother. June 1990 34: 1210-1213;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rhesus monkeys.
R F Schinazi, F D Boudinot, K J Doshi, and H M McClure
Antimicrob. Agents Chemother. June 1990 34: 1214-1219;
[Abstract] [PDF] [Reprints and Permissions]

Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032).
P Canepari, M Boaretti, M M Lleó, and G Satta
Antimicrob. Agents Chemother. June 1990 34: 1220-1226;
[Abstract] [PDF] [Reprints and Permissions]

Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users.
P M Small and H F Chambers
Antimicrob. Agents Chemother. June 1990 34: 1227-1231;
[Abstract] [PDF] [Reprints and Permissions]

Eradication of Helicobacter mustelae from the ferret stomach: an animal model of Helicobacter (Campylobacter) pylori chemotherapy.
G Otto, J G Fox, P Y Wu, and N S Taylor
Antimicrob. Agents Chemother. June 1990 34: 1232-1236;
[Abstract] [PDF] [Reprints and Permissions]

Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides.
S W Mamber, K W Brookshire, and S Forenza
Antimicrob. Agents Chemother. June 1990 34: 1237-1243;
[Abstract] [PDF] [Reprints and Permissions]

Dissemination of amikacin resistance gene aphA6 in Acinetobacter spp.
T Lambert, G Gerbaud, P Bouvet, J F Vieu, and P Courvalin
Antimicrob. Agents Chemother. June 1990 34: 1244-1248;
[Abstract] [PDF] [Reprints and Permissions]

Safety of fleroxacin coadministered with theophylline to young and elderly volunteers.
M Parent, M St-Laurent, and M LeBel
Antimicrob. Agents Chemother. June 1990 34: 1249-1253;
[Abstract] [PDF] [Reprints and Permissions]

Influence of lomefloxacin on the pharmacokinetics of theophylline.
M LeBel, F Vallée, and M St-Laurent
Antimicrob. Agents Chemother. June 1990 34: 1254-1256;
[Abstract] [PDF] [Reprints and Permissions]

Effects of supraphysiologic temperature and broth dilution on serum protein binding.
R L White, M B Kays, T A Armstrong, and L V Friedrich
Antimicrob. Agents Chemother. June 1990 34: 1257-1258;
[Abstract] [PDF] [Reprints and Permissions]

6-(3,4-Dichlorophenoxy)-3-(ethylthio)-2-pyridincarbonitrile inhibits poliovirus uncoating.
M E González, M J Almela, M Yacout, and L Carrasco
Antimicrob. Agents Chemother. June 1990 34: 1259-1261;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activities of irloxacin and E-3846, two new quinolones.
J A García-Rodríguez, J E García Sánchez, J L Muñoz Bellido, and I Trujillano
Antimicrob. Agents Chemother. June 1990 34: 1262-1267;
[Abstract] [PDF] [Reprints and Permissions]

Influence of temperature on degradation kinetics of ceftriaxone in diluted and undiluted human serum.
M J Esteban, E Cantón, and F Rius
Antimicrob. Agents Chemother. June 1990 34: 1268-1270;
[Abstract] [PDF] [Reprints and Permissions]

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.
H Yoshida, M Bogaki, M Nakamura, and S Nakamura
Antimicrob. Agents Chemother. June 1990 34: 1271-1272;
[Abstract] [PDF] [Reprints and Permissions]

Proportion of DNA gyrase mutants among quinolone-resistant strains of Pseudomonas aeruginosa.
H Yoshida, M Nakamura, M Bogaki, and S Nakamura
Antimicrob. Agents Chemother. June 1990 34: 1273-1275;
[Abstract] [PDF] [Reprints and Permissions]

Influence of plasma exchange pheresis on plasma elimination of ceftriaxone.
J S Bakken, S J Cavalieri, and D Gangeness
Antimicrob. Agents Chemother. June 1990 34: 1276-1277;
[Abstract] [PDF] [Reprints and Permissions]

Mobilization of the gentamicin resistance gene in Enterococcus faecalis.
S L Hodel-Christian and B E Murray
Antimicrob. Agents Chemother. June 1990 34: 1278-1280;
[Abstract] [PDF] [Reprints and Permissions]

Penetration of SCH-39304, a new antifungal triazole, into cerebrospinal fluid of primates.
T J Walsh, C Lester-McCully, M G Rinaldi, J E Wallace, F M Balis, J W Lee, P A Pizzo, and D G Poplack
Antimicrob. Agents Chemother. June 1990 34: 1281-1284;
[Abstract] [PDF] [Reprints and Permissions]

Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.
D A Leib, K L Ruffner, C Hildebrand, P A Schaffer, G E Wright, and D M Coen
Antimicrob. Agents Chemother. June 1990 34: 1285-1286;
[Abstract] [PDF] [Reprints and Permissions]

Evidence for a staphylococcal-like mercury resistance gene in Enterococcus faecalis.
K K Zscheck and B E Murray
Antimicrob. Agents Chemother. June 1990 34: 1287-1289;
[Abstract] [PDF] [Reprints and Permissions]

Failure of ceftazidime-amikacin therapy for bacteremia and meningitis due to Klebsiella pneumoniae producing an extended-spectrum beta-lactamase.
C E Smith, B S Tillman, A W Howell, R N Longfield, and J H Jorgensen
Antimicrob. Agents Chemother. June 1990 34: 1290-1293;
[Abstract] [PDF] [Reprints and Permissions]

Emergence of aminoglycoside resistance genes aadA and aadE in the genus Campylobacter.
H Pinto-Alphandary, C Mabilat, and P Courvalin
Antimicrob. Agents Chemother. June 1990 34: 1294-1296;
[Abstract] [PDF] [Reprints and Permissions]

Activities of (-)-carbovir and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro.
S G Carter, J A Kessler, and C D Rankin
Antimicrob. Agents Chemother. June 1990 34: 1297-1300;
[Abstract] [PDF] [Reprints and Permissions]

Errata:

Penetration of Clindamycin, Cefoxitin, and Metronidazole into Pelvic Peritoneal Fluid of Women Undergoing Diagnostic Laparoscopy
Stephen A. Berger, Michael Kupferminc, Joseph B. Lessing, Alfred Gorea, Ilan Gull, and M. Reuben Peyser
Antimicrob. Agents Chemother. June 1990 34: 1301
[PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.