AAC -- Table of Contents (June 1 1991, 35 [6])

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Contents: June 1991, Volume 35, Issue 6

       Research Article

       Experimental Therapeutics

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Table of Contents

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To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Research Article:

Genotypic approach to the study of bacterial resistance to antibiotics.
P Courvalin
Antimicrob. Agents Chemother. June 1991 35: 1019-1023;
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Prophylactic and therapeutic activities of azithromycin in a mouse model of pneumococcal pneumonia.
E Azoulay-Dupuis, E Vallée, J P Bedos, M Muffat-Joly, and J J Pocidalo
Antimicrob. Agents Chemother. June 1991 35: 1024-1028;
[Abstract] [PDF] [Reprints and Permissions]

Single-dose pharmacokinetics and tolerance of a cholesteryl sulfate complex of amphotericin B administered to healthy volunteers.
S W Sanders, K N Buchi, M S Goddard, J K Lang, and K G Tolman
Antimicrob. Agents Chemother. June 1991 35: 1029-1034;
[Abstract] [PDF] [Reprints and Permissions]

Isoniazid inhibition of mycolic acid synthesis by cell extracts of sensitive and resistant strains of Mycobacterium aurum.
A Quémard, C Lacave, and G Lanéelle
Antimicrob. Agents Chemother. June 1991 35: 1035-1039;
[Abstract] [PDF] [Reprints and Permissions]

Binding affinities of structurally related human rhinovirus capsid-binding compounds are related to their activities against human rhinovirus type 14.
M P Fox, M A McKinlay, G D Diana, and F J Dutko
Antimicrob. Agents Chemother. June 1991 35: 1040-1047;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of carumonam (AMA-1080) in patients with impaired renal function and in those undergoing hemodialysis.
K Konishi, H Suzuki, T Saruta, N Deguchi, and T Fugono
Antimicrob. Agents Chemother. June 1991 35: 1048-1052;
[Abstract] [PDF] [Reprints and Permissions]

Mechanisms of clinical resistance to fluoroquinolones in Enterococcus faecalis.
N Nakanishi, S Yoshida, H Wakebe, M Inoue, and S Mitsuhashi
Antimicrob. Agents Chemother. June 1991 35: 1053-1059;
[Abstract] [PDF] [Reprints and Permissions]

Three-dimensional analysis of the synergistic cytotoxicity of ganciclovir and zidovudine.
M N Prichard, L E Prichard, W A Baguley, M R Nassiri, and C Shipman, Jr
Antimicrob. Agents Chemother. June 1991 35: 1060-1065;
[Abstract] [PDF] [Reprints and Permissions]

Application of mathematical model to multiple-dose experimental chemotherapy for fatal murine pneumonia.
T Hishikawa, T Kusunoki, K Tsuchiya, Y Uzuka, T Sakamoto, T Nagatake, and K Matsumoto
Antimicrob. Agents Chemother. June 1991 35: 1066-1069;
[Abstract] [PDF] [Reprints and Permissions]

Evidence that amikacin ototoxicity is related to total perilymph area under the concentration-time curve regardless of concentration.
A R Beaubien, E Ormsby, A Bayne, K Carrier, G Crossfield, M Downes, R Henri, and M Hodgen
Antimicrob. Agents Chemother. June 1991 35: 1070-1074;
[Abstract] [PDF] [Reprints and Permissions]

Antimicrobial susceptibility and molecular epidemiology of beta-lactamase-producing, aminoglycoside-resistant isolates of Enterococcus faecalis.
S M Markowitz, V D Wells, D S Williams, C G Stuart, P E Coudron, and E S Wong
Antimicrob. Agents Chemother. June 1991 35: 1075-1080;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics and tissue penetration of tazobactam administered alone and with piperacillin.
R Wise, M Logan, M Cooper, and J M Andrews
Antimicrob. Agents Chemother. June 1991 35: 1081-1084;
[Abstract] [PDF] [Reprints and Permissions]

Effects of amoxicillin-clavulanate combination on the motility of the small intestine in human beings.
F Caron, P Ducrotte, E Lerebours, R Colin, G Humbert, and P Denis
Antimicrob. Agents Chemother. June 1991 35: 1085-1088;
[Abstract] [PDF] [Reprints and Permissions]

Comparative effect of protein binding on the killing activities of teicoplanin and vancomycin.
E M Bailey, M J Rybak, and G W Kaatz
Antimicrob. Agents Chemother. June 1991 35: 1089-1092;
[Abstract] [PDF] [Reprints and Permissions]

Association of two resistance mechanisms in a clinical isolate of Enterobacter cloacae with high-level resistance to imipenem.
E H Lee, M H Nicolas, M D Kitzis, G Pialoux, E Collatz, and L Gutmann
Antimicrob. Agents Chemother. June 1991 35: 1093-1098;
[Abstract] [PDF] [Reprints and Permissions]

Structure-activity relationships of pentamidine analogs against Giardia lamblia and correlation of antigiardial activity with DNA-binding affinity.
C A Bell, M Cory, T A Fairley, J E Hall, and R R Tidwell
Antimicrob. Agents Chemother. June 1991 35: 1099-1107;
[Abstract] [PDF] [Reprints and Permissions]

In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile.
R N Swanson, D J Hardy, N L Shipkowitz, C W Hanson, N C Ramer, P B Fernandes, and J J Clement
Antimicrob. Agents Chemother. June 1991 35: 1108-1111;
[Abstract] [PDF] [Reprints and Permissions]

Ocular kinetics of pefloxacin after intramuscular administration in albino and pigmented rabbits.
I Cochereau-Massin, J Bauchet, F Faurisson, J M Vallois, P Lacombe, and J J Pocidalo
Antimicrob. Agents Chemother. June 1991 35: 1112-1115;
[Abstract] [PDF] [Reprints and Permissions]

Synthesis and antimicrobial evaluation of dirithromycin (AS-E 136; LY237216), a new macrolide antibiotic derived from erythromycin.
F T Counter, P W Ensminger, D A Preston, C Y Wu, J M Greene, A M Felty-Duckworth, J W Paschal, and H A Kirst
Antimicrob. Agents Chemother. June 1991 35: 1116-1126;
[Abstract] [PDF] [Reprints and Permissions]

Comparative efficacy and safety of cefprozil (BMY-28100) and cefaclor in the treatment of acute group A beta-hemolytic streptococcal pharyngitis.
J C Christenson, E Swenson, W M Gooch, 3rd, and J N Herrod
Antimicrob. Agents Chemother. June 1991 35: 1127-1130;
[Abstract] [PDF] [Reprints and Permissions]

Significance of inducible cephalosporinase remaining in the experimentally infected rat granuloma pouch after beta-lactam therapy.
H Araki, S Minami, Y Watanabe, and T Yasuda
Antimicrob. Agents Chemother. June 1991 35: 1131-1136;
[Abstract] [PDF] [Reprints and Permissions]

Effect of a new quinolone, sparfloxacin, on the pharmacokinetics of theophylline in asthmatic patients.
K Takagi, K Yamaki, M Nadai, T Kuzuya, and T Hasegawa
Antimicrob. Agents Chemother. June 1991 35: 1137-1141;
[Abstract] [PDF] [Reprints and Permissions]

Hippocampal activity in the presence of quinolones and fenbufen in vitro.
W Dimpfel, M Spüler, A Dalhoff, W Hofmann, and G Schlüter
Antimicrob. Agents Chemother. June 1991 35: 1142-1146;
[Abstract] [PDF] [Reprints and Permissions]

Characterization of the gentamicin resistance transposon Tn5281 from Enterococcus faecalis and comparison to staphylococcal transposons Tn4001 and Tn4031.
S L Hodel-Christian and B E Murray
Antimicrob. Agents Chemother. June 1991 35: 1147-1152;
[Abstract] [PDF] [Reprints and Permissions]

Beta-lactam antibiotics potentiate magainin 2 antimicrobial activity in vitro and in vivo.
R P Darveau, M D Cunningham, C L Seachord, L Cassiano-Clough, W L Cosand, J Blake, and C S Watkins
Antimicrob. Agents Chemother. June 1991 35: 1153-1159;
[Abstract] [PDF] [Reprints and Permissions]

Drug level monitoring in a double-blind multicenter trial: false-positive zidovudine measurements in AIDS clinical trials group protocol 019.
D J Krogstad, M R Eveland, L L Lim, P A Volberding, and B M Sadler
Antimicrob. Agents Chemother. June 1991 35: 1160-1164;
[Abstract] [PDF] [Reprints and Permissions]

Metabolic disposition and pharmacokinetics of the antiviral agent 6-methoxypurine arabinoside in rats and monkeys.
T C Burnette, G W Koszalka, T A Krenitsky, and P De Miranda
Antimicrob. Agents Chemother. June 1991 35: 1165-1173;
[Abstract] [PDF] [Reprints and Permissions]

Imipenem- and meropenem-resistant mutants of Enterobacter cloacae and Proteus rettgeri lack porins.
A Raimondi, A Traverso, and H Nikaido
Antimicrob. Agents Chemother. June 1991 35: 1174-1180;
[Abstract] [PDF] [Reprints and Permissions]

In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.
K B Waites, L B Duffy, T Schmid, D Crabb, M S Pate, and G H Cassell
Antimicrob. Agents Chemother. June 1991 35: 1181-1185;
[Abstract] [PDF] [Reprints and Permissions]

Comparison of the effects of the new azalide antibiotic, azithromycin, and erythromycin estolate on rat liver cytochrome P-450.
D E Amacher, S J Schomaker, and J A Retsema
Antimicrob. Agents Chemother. June 1991 35: 1186-1190;
[Abstract] [PDF] [Reprints and Permissions]

Kinetics and dynamics of tobramycin action in patients with bacteriuria given single doses.
C A Peloquin, T J Cumbo, and J J Schentag
Antimicrob. Agents Chemother. June 1991 35: 1191-1195;
[Abstract] [PDF] [Reprints and Permissions]

Comparison of spiral gradient and conventional agar dilution for susceptibility testing of anaerobic bacteria.
H M Wexler, E Molitoris, F Jashnian, and S M Finegold
Antimicrob. Agents Chemother. June 1991 35: 1196-1202;
[Abstract] [PDF] [Reprints and Permissions]

Increased susceptibility to beta-lactam antibiotics and decreased porin content caused by envB mutations of Salmonella typhimurium.
O J Oppezzo, B Avanzati, and D N Antón
Antimicrob. Agents Chemother. June 1991 35: 1203-1207;
[Abstract] [PDF] [Reprints and Permissions]

Comparative pharmacokinetics of amphotericin B after administration of a novel colloidal delivery system, ABCD, and a conventional formulation to rats.
R M Fielding, P C Smith, L H Wang, J Porter, and L S Guo
Antimicrob. Agents Chemother. June 1991 35: 1208-1213;
[Abstract] [PDF] [Reprints and Permissions]

Susceptibilities of 394 Bacteroides fragilis, non-B. fragilis group Bacteroides species, and Fusobacterium species to newer antimicrobial agents.
P C Appelbaum, S K Spangler, and M R Jacobs
Antimicrob. Agents Chemother. June 1991 35: 1214-1218;
[Abstract] [PDF] [Reprints and Permissions]

Effect of beta-lactamase inhibitors on the activities of various beta-lactam agents against anaerobic bacteria.
H M Wexler, E Molitoris, and S M Finegold
Antimicrob. Agents Chemother. June 1991 35: 1219-1224;
[Abstract] [PDF] [Reprints and Permissions]

Susceptibility of Pneumocystis carinii to artemisinin in vitro.
S Merali and S R Meshnick
Antimicrob. Agents Chemother. June 1991 35: 1225-1227;
[Abstract] [PDF] [Reprints and Permissions]

Cocaine hydrochloride and benzoylecgonine have no in vitro inhibitory effect against Neisseria gonorrhoeae.
J M Zenilman, C A Reichart, T M Neumann, and E W Hook, 3rd
Antimicrob. Agents Chemother. June 1991 35: 1228-1229;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activity of metronidazole against Helicobacter pylori as determined by agar dilution and agar diffusion.
C C Knapp, M D Ludwig, and J A Washington
Antimicrob. Agents Chemother. June 1991 35: 1230-1231;
[Abstract] [PDF] [Reprints and Permissions]

In vitro activities of aminoglycosides, lincosamides, and rifamycins against Mycobacterium leprae.
S G Franzblau
Antimicrob. Agents Chemother. June 1991 35: 1232-1234;
[Abstract] [PDF] [Reprints and Permissions]

In vitro susceptibility testing procedures for fosfomycin tromethamine.
A L Barry and P C Fuchs
Antimicrob. Agents Chemother. June 1991 35: 1235-1238;
[Abstract] [PDF] [Reprints and Permissions]

Accidental overdose of intravenous ofloxacin with benign outcome.
R B Kohler, N Arkins, and K J Tack
Antimicrob. Agents Chemother. June 1991 35: 1239-1240;
[Abstract] [PDF] [Reprints and Permissions]

Long-term prophylaxis with norfloxacin versus nitrofurantoin in women with recurrent urinary tract infection.
R Raz and S Boger
Antimicrob. Agents Chemother. June 1991 35: 1241-1242;
[Abstract] [PDF] [Reprints and Permissions]

In vitro and in vivo studies of ME1228, a new parenteral cephalosporin with potent activity against Pseudomonas aeruginosa.
S Miyazaki, Y Miyazaki, A Tsuji, M Nishida, and S Goto
Antimicrob. Agents Chemother. June 1991 35: 1245-1246;
[Abstract] [PDF] [Reprints and Permissions]

Pharmacokinetics of 2',3'-dideoxyinosine in monkeys.
M X Qian, T S Finco, A R Swagler, and J M Gallo
Antimicrob. Agents Chemother. June 1991 35: 1247-1249;
[Abstract] [PDF] [Reprints and Permissions]

Differential inhibition of 2'-deoxycytidine salvage as a possible mechanism for potentiation of the anti-human immunodeficiency virus activity of 2',3'-dideoxycytidine by dipyridamole.
S S Patel, J Szebeni, L M Wahl, and J N Weinstein
Antimicrob. Agents Chemother. June 1991 35: 1250-1253;
[Abstract] [PDF] [Reprints and Permissions]

Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs.
E Matthes, K Reimer, M von Janta-Lipinski, H Meisel, and C Lehmann
Antimicrob. Agents Chemother. June 1991 35: 1254-1257;
[Abstract] [PDF] [Reprints and Permissions]

Use of slime dispersants to promote antibiotic penetration through the extracellular polysaccharide of mucoid Pseudomonas aeruginosa.
C A Gordon, N A Hodges, and C Marriott
Antimicrob. Agents Chemother. June 1991 35: 1258-1260;
[Abstract] [PDF] [Reprints and Permissions]

Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus.
R J Davidson, G G Zhanel, R Phillips, and D J Hoban
Antimicrob. Agents Chemother. June 1991 35: 1261-1263;
[Abstract] [PDF] [Reprints and Permissions]

Use of high-performance liquid chromatography to monitor stability of tetracycline and chlortetracycline in susceptibility determinations.
A Ray and V Newton
Antimicrob. Agents Chemother. June 1991 35: 1264-1266;
[Abstract] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

Efficacy of Different ß-Lactams against an Extended-Spectrum ß-Lactamase-Producing Klebsiella pneumoniae Strain in the Rat Intra-Abdominal Abscess Model
Louis B. Rice, Joseph D. C. Yao, Karin Klimm, George M. Eliopoulos, and Robert C. Moellering, Jr.
Antimicrob. Agents Chemother. June 1991 35: 1243-1244;
[Abstract] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.