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Research Article:

H Anwar, J L Strap, and J W Costerton

Establishment of aging biofilms: possible mechanism of bacterial resistance to antimicrobial therapy.
Antimicrob. Agents Chemother. 1992 36: 1347-1351. [PDF] [Reprints and Permissions]  

K Oishi, F Sonoda, A Iwagaki, S Kobayashi, T Nagatake, and K Matsumoto

Effects of the combination of lipopolysaccharide-specific monoclonal antibodies and sparfloxacin against Pseudomonas aeruginosa pneumonia in neutropenic mice.
Antimicrob. Agents Chemother. 1992 36: 1352-1357. [Abstract] [PDF] [Reprints and Permissions]  

T Iwahi, K Okonogi, T Yamazaki, S Shiki, M Kondo, A Miyake, and A Imada

In vitro and in vivo activities of SCE-2787, a new parenteral cephalosporin with a broad antibacterial spectrum.
Antimicrob. Agents Chemother. 1992 36: 1358-1366. [Abstract] [PDF] [Reprints and Permissions]  

B Berger-Bächi, A Strässle, J E Gustafson, and F H Kayser

Mapping and characterization of multiple chromosomal factors involved in methicillin resistance in Staphylococcus aureus.
Antimicrob. Agents Chemother. 1992 36: 1367-1373. [Abstract] [PDF] [Reprints and Permissions]  

G Ranaldi, K Islam, and Y Sambuy

Epithelial cells in culture as a model for the intestinal transport of antimicrobial agents.
Antimicrob. Agents Chemother. 1992 36: 1374-1381. [Abstract] [PDF] [Reprints and Permissions]  

R H Barbhaiya, C A Knupp, M Pfeffer, and K A Pittman

Lack of pharmacokinetic interaction between cefepime and amikacin in humans.
Antimicrob. Agents Chemother. 1992 36: 1382-1386. [Abstract] [PDF] [Reprints and Permissions]  

R H Barbhaiya, C A Knupp, M Pfeffer, D Zaccardelli, G M Dukes, W Mattern, K A Pittman, and L J Hak

Pharmacokinetics of cefepime in patients undergoing continuous ambulatory peritoneal dialysis.
Antimicrob. Agents Chemother. 1992 36: 1387-1391. [Abstract] [PDF] [Reprints and Permissions]  

S Vincent, P Minkler, B Bincziewski, L Etter, and D M Shlaes

Vancomycin resistance in Enterococcus gallinarum.
Antimicrob. Agents Chemother. 1992 36: 1392-1399. [Abstract] [PDF] [Reprints and Permissions]  

S A Signs, J S Tan, S J Salstrom, and T M File

Pharmacokinetics of imipenem in serum and skin window fluid in healthy adults after intramuscular or intravenous administration.
Antimicrob. Agents Chemother. 1992 36: 1400-1403. [Abstract] [PDF] [Reprints and Permissions]  

F Bressolle, J E de la Coussaye, R Ayoub, D Fabre, R Gomeni, G Saissi, J J Eledjam, and M Galtier

Endotracheal and aerosol administrations of ceftazidime in patients with nosocomial pneumonia: pharmacokinetics and absolute bioavailability.
Antimicrob. Agents Chemother. 1992 36: 1404-1411. [Abstract] [PDF] [Reprints and Permissions]  

E Vallée, E Azoulay-Dupuis, J J Pocidalo, and E Bergogne-Bérézin

Activity and local delivery of azithromycin in a mouse model of Haemophilus influenzae lung infection.
Antimicrob. Agents Chemother. 1992 36: 1412-1417. [Abstract] [PDF] [Reprints and Permissions]  

H C Neu, J W Gu, W Fang, and N X Chin

In vitro activity and beta-lactamase stability of LJC 10,627.
Antimicrob. Agents Chemother. 1992 36: 1418-1423. [Abstract] [PDF] [Reprints and Permissions]  

J M Quale, J J O'Halloran, N DeVincenzo, and R H Barth

Removal of vancomycin by high-flux hemodialysis membranes.
Antimicrob. Agents Chemother. 1992 36: 1424-1426. [Abstract] [PDF] [Reprints and Permissions]  

G Woodnutt, V Berry, and L Mizen

Simulation of human serum pharmacokinetics of cefazolin, piperacillin, and BRL 42715 in rats and efficacy against experimental intraperitoneal infections.
Antimicrob. Agents Chemother. 1992 36: 1427-1431. [Abstract] [PDF] [Reprints and Permissions]  

M Hosoya, S Matsuyama, M Baba, H Suzuki, and S Shigeta

Effects of protease inhibitors on replication of various myxoviruses.
Antimicrob. Agents Chemother. 1992 36: 1432-1436. [Abstract] [PDF] [Reprints and Permissions]  

B Ljungberg and I Nilsson-Ehle

Pharmacokinetics of meropenem and its metabolite in young and elderly healthy men.
Antimicrob. Agents Chemother. 1992 36: 1437-1440. [Abstract] [PDF] [Reprints and Permissions]  

J H Condra, E A Emini, L Gotlib, D J Graham, A J Schlabach, J A Wolfgang, R J Colonno, and V V Sardana

Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors.
Antimicrob. Agents Chemother. 1992 36: 1441-1446. [Abstract] [PDF] [Reprints and Permissions]  

K J Shaw, P N Rather, F J Sabatelli, P Mann, H Munayyer, R Mierzwa, G L Petrikkos, R S Hare, G H Miller, and P Bennett

Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens.
Antimicrob. Agents Chemother. 1992 36: 1447-1455. [Abstract] [PDF] [Reprints and Permissions]  

J C Mertens, P W van Barneveld, H R Asin, E Ligtvoet, M R Visser, T Branger, and A I Hoepelman

Double-blind randomized study comparing the efficacies and safeties of a short (3-day) course of azithromycin and a 5-day course of amoxicillin in patients with acute exacerbations of chronic bronchitis.
Antimicrob. Agents Chemother. 1992 36: 1456-1459. [Abstract] [PDF] [Reprints and Permissions]  

M Ohta, H Ito, K Masuda, S Tanaka, Y Arakawa, R Wacharotayankun, and N Kato

Mechanisms of antibacterial action of tachyplesins and polyphemusins, a group of antimicrobial peptides isolated from horseshoe crab hemocytes.
Antimicrob. Agents Chemother. 1992 36: 1460-1465. [Abstract] [PDF] [Reprints and Permissions]  

B E Gilbert, P R Wyde, and S Z Wilson

Aerosolized liposomal amphotericin B for treatment of pulmonary and systemic Cryptococcus neoformans infections in mice.
Antimicrob. Agents Chemother. 1992 36: 1466-1471. [Abstract] [PDF] [Reprints and Permissions]  

X B Kong, P Vidal, W P Tong, J Chiang, C A Gloff, and T C Chou

Preclinical pharmacology and pharmacokinetics of the anti-hepatitis virus agent 2'-fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil in mice and rats.
Antimicrob. Agents Chemother. 1992 36: 1472-1477. [Abstract] [PDF] [Reprints and Permissions]  

D L Patton, S K Wang, and C C Kuo

In vitro activity of nonoxynol 9 on HeLa 229 cells and primary monkey cervical epithelial cells infected with Chlamydia trachomatis.
Antimicrob. Agents Chemother. 1992 36: 1478-1482. [Abstract] [PDF] [Reprints and Permissions]  

R Doi, K Inoue, K Hara, and T Tobe

Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery.
Antimicrob. Agents Chemother. 1992 36: 1483-1486. [Abstract] [PDF] [Reprints and Permissions]  

D Billot-Klein, L Gutmann, E Collatz, and J van Heijenoort

Analysis of peptidoglycan precursors in vancomycin-resistant enterococci.
Antimicrob. Agents Chemother. 1992 36: 1487-1490. [Abstract] [PDF] [Reprints and Permissions]  

K Sato, K Hoshino, M Tanaka, I Hayakawa, and Y Osada

Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates.
Antimicrob. Agents Chemother. 1992 36: 1491-1498. [Abstract] [PDF] [Reprints and Permissions]  

A Viganò, N Principi, L Brivio, P Tommasi, P Stasi, and A D Villa

Comparison of 5 milligrams of netilmicin per kilogram of body weight once daily versus 2 milligrams per kilogram thrice daily for treatment of gram-negative pyelonephritis in children.
Antimicrob. Agents Chemother. 1992 36: 1499-1503. [Abstract] [PDF] [Reprints and Permissions]  

N Clairoux, M Picard, A Brochu, N Rousseau, P Gourde, D Beauchamp, T R Parr, Jr, M G Bergeron, and F Malouin

Molecular basis of the non-beta-lactamase-mediated resistance to beta-lactam antibiotics in strains of Haemophilus influenzae isolated in Canada.
Antimicrob. Agents Chemother. 1992 36: 1504-1513. [Abstract] [PDF] [Reprints and Permissions]  

G D Wright, C Molinas, M Arthur, P Courvalin, and C T Walsh

Characterization of vanY, a DD-carboxypeptidase from vancomycin-resistant Enterococcus faecium BM4147.
Antimicrob. Agents Chemother. 1992 36: 1514-1518. [Abstract] [PDF] [Reprints and Permissions]  

E Singlas, A M Taburet, F Borsa Lebas, O Parent de Curzon, A Sobel, P Chauveau, B Viron, R al Khayat, J L Poignet, and F Mignon

Didanosine pharmacokinetics in patients with normal and impaired renal function: influence of hemodialysis.
Antimicrob. Agents Chemother. 1992 36: 1519-1524. [Abstract] [PDF] [Reprints and Permissions]  

C Tasset, V Preat, A Bernard, and M Roland

Comparison of nephrotoxicities of different polyoxyethyleneglycol formulations of amphotericin B in rats.
Antimicrob. Agents Chemother. 1992 36: 1525-1531. [Abstract] [PDF] [Reprints and Permissions]  

B A Christensson, I Nilsson-Ehle, M Hutchison, S J Haworth, B Oqvist, and S R Norrby

Pharmacokinetics of meropenem in subjects with various degrees of renal impairment.
Antimicrob. Agents Chemother. 1992 36: 1532-1537. [Abstract] [PDF] [Reprints and Permissions]  

J M Karle, I L Karle, L Gerena, and W K Milhous

Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum.
Antimicrob. Agents Chemother. 1992 36: 1538-1544. [Abstract] [PDF] [Reprints and Permissions]  

S L Hill, D Burnett, A L Lovering, and R A Stockley

Use of an enzyme-linked immunosorbent assay to assess penetration of amoxicillin into lung secretions.
Antimicrob. Agents Chemother. 1992 36: 1545-1552. [Abstract] [PDF] [Reprints and Permissions]  

S M Borcherding, T L Bastian, T H Self, N Abou-Shala, B W LeDuc, and R L Lalonde

Two- and four-day rifampin chemoprophylaxis regimens induce oxidative metabolism.
Antimicrob. Agents Chemother. 1992 36: 1553-1558. [Abstract] [PDF] [Reprints and Permissions]  

J J Eron, Jr, V A Johnson, D P Merrill, T C Chou, and M S Hirsch

Synergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitro.
Antimicrob. Agents Chemother. 1992 36: 1559-1562. [Abstract] [PDF] [Reprints and Permissions]  

H S Fraimow and E Venuti

Inconsistent bactericidal activity of triple-combination therapy with vancomycin, ampicillin, and gentamicin against vancomycin-resistant, highly ampicillin-resistant Enterococcus faecium.
Antimicrob. Agents Chemother. 1992 36: 1563-1566. [Abstract] [PDF] [Reprints and Permissions]  

F de Lalla, R Maserati, P Scarpellini, P Marone, R Nicolin, F Caccamo, and R Rigoli

Clarithromycin-ciprofloxacin-amikacin for therapy of Mycobacterium avium-Mycobacterium intracellulare bacteremia in patients with AIDS.
Antimicrob. Agents Chemother. 1992 36: 1567-1569. [Abstract] [PDF] [Reprints and Permissions]  

D Shonekan, D Mildvan, and S Handwerger

Comparative in vitro activities of teicoplanin, daptomycin, ramoplanin, vancomycin, and PD127,391 against blood isolates of gram-positive cocci.
Antimicrob. Agents Chemother. 1992 36: 1570-1572. [Abstract] [PDF] [Reprints and Permissions]  

M R Hammerschlag, K K Qumei, and P M Roblin

In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae.
Antimicrob. Agents Chemother. 1992 36: 1573-1574. [Abstract] [PDF] [Reprints and Permissions]  

W R Outman, R E Levitz, D A Hill, and C H Nightingale

Intraocular penetration of rifampin in humans.
Antimicrob. Agents Chemother. 1992 36: 1575-1576. [Abstract] [PDF] [Reprints and Permissions]  

M Fukasawa, Y Sumita, E T Harabe, T Tanio, H Nouda, T Kohzuki, T Okuda, H Matsumura, and M Sunagawa

Stability of meropenem and effect of 1 beta-methyl substitution on its stability in the presence of renal dehydropeptidase I.
Antimicrob. Agents Chemother. 1992 36: 1577-1579. [Abstract] [PDF] [Reprints and Permissions]  

J S Goodman

Ticarcillin-clavulanic acid dosing ratio for treatment of experimental Staphylococcus aureus endocarditis.
Antimicrob. Agents Chemother. 1992 36: 1585. [PDF] [Reprints and Permissions]  

F C Tenover and L K McDougal

Detecting methicillin resistance in Staphylococcus aureus by polymerase chain reaction.
Antimicrob. Agents Chemother. 1992 36: 1585-1586. [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Masaru Satoh, Kei-Ichi Munakata, Hideo Takeuchi, and Osamu Yoshida

Evaluation of the Usefulness of a Novel Injectable Cephalosporin, E1040, and Ceftazidime for Management of Complicated Urinary Tract Infections Caused by Pseudomonas aeruginosa and Proteus mirabilis by Using the Rat Urolithiasis Model
Antimicrob. Agents Chemother. 1992 36: 1580-1583. [Abstract] [PDF] [Reprints and Permissions]  

Recent Approvals:

Anti-Infective Agents, Biologics, and Vaccines Approved by the U.S. Food and Drug Administration in 1991
Antimicrob. Agents Chemother. 1992 36: 1584. [PDF] [Reprints and Permissions]  

Errata:

M. Nakashima, T. Uematsu, T. Oguma, T. Yoshida, K. Mizojiri, S. Matsuno, and S. Yamamoto

Phase I Clinical Studies of S-1108: Safety and Pharmacokinetics in a Multiple-Administration Study with Special Emphasis on the Influence on Carnitine Body Stores
Antimicrob. Agents Chemother. 1992 36: 1587. [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.