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Minireviews:

Irina Massova and Shahriar Mobashery

Kinship and Diversification of Bacterial Penicillin-Binding Proteins and -Lactamases
Antimicrob. Agents Chemother. 1998 42: 1-17. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Pier Carlo Braga and Davide Ricci

Atomic Force Microscopy: Application to Investigation of Escherichia coli Morphology before and after Exposure to Cefodizime
Antimicrob. Agents Chemother. 1998 42: 18-22. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey M. Libby

Postantibiotic Effect in Escherichia coli Determined with Real-Time Metabolic Monitoring
Antimicrob. Agents Chemother. 1998 42: 78-82. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Heike Brötz, Gabriele Bierbaum, Klaus Leopold, Peter E. Reynolds, and Hans-Georg Sahl

The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II
Antimicrob. Agents Chemother. 1998 42: 154-160. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Farid Sifaoui, Emmanuelle Varon, Marie-Dominique Kitzis, and Laurent Gutmann

In Vitro Activity of Sanfetrinem and Affinity for the Penicillin-Binding Proteins of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 1998 42: 173-175. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Takashi Fukuoka, Harumi Kawada, Akiko Kitayama, Tetsufumi Koga, Mikie Kubota, Tamako Harasaki, Yasuki Kamai, Satoshi Ohya, Hiroshi Yasuda, Masayuki Iwata, and Shogo Kuwahara

Efficacy of CS-834 against Experimental Pneumonia Caused by Penicillin-Susceptible and -Resistant Streptococcus pneumoniae in Mice
Antimicrob. Agents Chemother. 1998 42: 23-27. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takahisa Furuta, Hideyuki Muramatsu, Akihiko Fujie, Shiro Fujihira, Noor Rain Abudullah, and Somei Kojima

Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice
Antimicrob. Agents Chemother. 1998 42: 37-39. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takakazu Otsubo, Kazuo Maruyama, Shigefumi Maesaki, Yoshitsugu Miyazaki, Eitaro Tanaka, Tomoko Takizawa, Kunikazu Moribe, Kazunori Tomono, Takayoshi Tashiro, and Shigeru Kohno

Long-Circulating Immunoliposomal Amphotericin B against Invasive Pulmonary Aspergillosis in Mice
Antimicrob. Agents Chemother. 1998 42: 40-44. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bryan Charleston, John J. Gate, Ingrid A. Aitken, Bernd Stephan, and Robrecht Froyman

Comparison of the Efficacies of Three Fluoroquinolone Antimicrobial Agents, Given as Continuous or Pulsed-Water Medication, against Escherichia coli Infection in Chickens
Antimicrob. Agents Chemother. 1998 42: 83-87. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John R. Graybill, Laura K. Najvar, Annette Fothergill, Thomas Hardin, Michael Rinaldi, Chris Lambros, and Steven L. Regen

KY-62, a Polyene Analog of Amphotericin B, for Treatment of Murine Candidiasis
Antimicrob. Agents Chemother. 1998 42: 147-150. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John R. Graybill, Laura K. Najvar, Eleanor M. Montalbo, Francesco J. Barchiesi, Michael F. Luther, and Michael G. Rinaldi

Treatment of Histoplasmosis with MK-991 (L-743,872)
Antimicrob. Agents Chemother. 1998 42: 151-153. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luiz E. Bermudez, Mary Petrofsky, Peter Kolonoski, and Lowell S. Young

Emergence of Mycobacterium avium Populations Resistant to Macrolides during Experimental Chemotherapy
Antimicrob. Agents Chemother. 1998 42: 180-183. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Z. Montgomerie and D. G. Schick

Treatment of Enterococcal Pyelonephritis with Trovafloxacin and Rifampin: In Vitro-In Vivo Contrast
Antimicrob. Agents Chemother. 1998 42: 188-189. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

M. Wolff

Comparison of Strategies Using Cefpirome and Ceftazidime for Empiric Treatment of Pneumonia in Intensive Care Patients
Antimicrob. Agents Chemother. 1998 42: 28-36. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Chodosh, S. Lakshminarayan, H. Swarz, and S. Breisch

Efficacy and Safety of a 10-Day Course of 400 or 600 Milligrams of Grepafloxacin Once Daily for Treatment of Acute Bacterial Exacerbations of Chronic Bronchitis: Comparison with a 10-Day Course of 500 Milligrams of Ciprofloxacin Twice Daily
Antimicrob. Agents Chemother. 1998 42: 114-120. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. van Vugt, A. Brockman, B. Gemperli, C. Luxemburger, I. Gathmann, C. Royce, Thra Slight, S. Looareesuwan, N. J. White, and F. Nosten

Randomized Comparison of Artemether-Benflumetol and Artesunate-Mefloquine in Treatment of MultidrugResistant Falciparum Malaria
Antimicrob. Agents Chemother. 1998 42: 135-139. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Murray S. Webb, Nancy L. Boman, David J. Wiseman, Dawn Saxon, Kym Sutton, Kim F. Wong, Patricia Logan, and Michael J. Hope

Antibacterial Efficacy against an In Vivo Salmonella typhimurium Infection Model and Pharmacokinetics of a Liposomal Ciprofloxacin Formulation
Antimicrob. Agents Chemother. 1998 42: 45-52. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen H. Zinner, Deborah Gilbert, and Michael N. Dudley

Activity of Trovafloxacin (with or without Ampicillin-Sulbactam) against Enterococci in an In Vitro Dynamic Model of Infection
Antimicrob. Agents Chemother. 1998 42: 72-77. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ian R. Friedland, Eric Sultan, Karl H. Lehr, and Bernard Lenfant

Concentrations of Cefpirome in Cerebrospinal Fluid of Children with Bacterial Meningitis after a Single Intravenous Dose
Antimicrob. Agents Chemother. 1998 42: 199-201. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Carmen Peña, Miquel Pujol, Carmen Ardanuy, Asumpta Ricart, Roman Pallares, Josefina Liñares, Javier Ariza, and Francisco Gudiol

Epidemiology and Successful Control of a Large Outbreak Due to Klebsiella pneumoniae Producing ExtendedSpectrum -Lactamases
Antimicrob. Agents Chemother. 1998 42: 53-58. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Diane E. Taylor, Catharine A. Trieber, Gudrun Trescher, and Michelle Bekkering

Host Mutations (miaA and rpsL) Reduce Tetracycline Resistance Mediated by Tet(O) and Tet(M)
Antimicrob. Agents Chemother. 1998 42: 59-64. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ramakrishnan Srikumar, Tatiana Kon, Naomasa Gotoh, and Keith Poole

Expression of Pseudomonas aeruginosa Multidrug Efflux Pumps MexA-MexB-OprM and MexC-MexD-OprJ in a Multidrug-Sensitive Escherichia coli Strain
Antimicrob. Agents Chemother. 1998 42: 65-71. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gayatri Vedantam, Gordon G. Guay, Natasha E. Austria, Stella Z. Doktor, and Brian P. Nichols

Characterization of Mutations Contributing to Sulfathiazole Resistance in Escherichia coli
Antimicrob. Agents Chemother. 1998 42: 88-93. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Krzysztof Sieradzki, Paolo Villari, and Alexander Tomasz

Decreased Susceptibilities to Teicoplanin and Vancomycin among Coagulase-Negative Methicillin-Resistant Clinical Isolates of Staphylococci
Antimicrob. Agents Chemother. 1998 42: 100-107. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Claire Poyart, Pierre Mugnier, Gilles Quesne, Patrick Berche, and Patrick Trieu-Cuot

A Novel Extended-Spectrum TEM-Type -Lactamase (TEM-52) Associated with Decreased Susceptibility to Moxalactam in Klebsiella pneumoniae
Antimicrob. Agents Chemother. 1998 42: 108-113. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bénédicte Fournier and David C. Hooper

Mutations in Topoisomerase IV and DNA Gyrase of Staphylococcus aureus: Novel Pleiotropic Effects on Quinolone and Coumarin Activity
Antimicrob. Agents Chemother. 1998 42: 121-128. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naoki Matsumura, Shinzaburo Minami, and Susumu Mitsuhashi

Sequences of Homologous -Lactamases from Clinical Isolates of Serratia marcescens with Different Substrate Specificities
Antimicrob. Agents Chemother. 1998 42: 176-179. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeong Hoon Kim, Eun Hee Cho, Kwang Seo Kim, Hak Yeop Kim, and Young Min Kim

Cloning and Nucleotide Sequence of the DNA Gyrase gyrA Gene from Serratia marcescens and Characterization of Mutations in gyrA of Quinolone-Resistant Clinical Isolates
Antimicrob. Agents Chemother. 1998 42: 190-193. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Glenn W. Kaatz and Susan M. Seo

Topoisomerase Mutations in Fluoroquinolone-Resistant and Methicillin-Susceptible and -Resistant Clinical Isolates of Staphylococcus aureus
Antimicrob. Agents Chemother. 1998 42: 197-198. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robin Patel, Jim R. Uhl, Peggy Kohner, Marlene K. Hopkins, James M. Steckelberg, Bruce Kline, and Franklin R. Cockerill, III

DNA Sequence Variation within vanA, vanB, vanC-1, and vanC-2/3 Genes of Clinical Enterococcus Isolates
Antimicrob. Agents Chemother. 1998 42: 202-205. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Masakatsu Tsuji, Yoshikazu Ishii, Akira Ohno, Shuichi Miyazaki, and Keizo Yamaguchi

In Vitro and In Vivo Antibacterial Activities of S-4661, a New Carbapenem
Antimicrob. Agents Chemother. 1998 42: 94-99. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John H. Rex, Page W. Nelson, Victor L. Paetznick, Mario Lozano-Chiu, A. Espinel-Ingroff, and Elias J. Anaissie

Optimizing the Correlation between Results of Testing In Vitro and Therapeutic Outcome In Vivo for Fluconazole by Testing Critical Isolates in a Murine Model of Invasive Candidiasis
Antimicrob. Agents Chemother. 1998 42: 129-134. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Marco, M. A. Pfaller, S. Messer, and R. N. Jones

In Vitro Activities of Voriconazole (UK-109,496) and Four Other Antifungal Agents against 394 Clinical Isolates of Candida spp.
Antimicrob. Agents Chemother. 1998 42: 161-163. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Nzila-Mounda, E. K. Mberu, C. H. Sibley, C. V. Plowe, P. A. Winstanley, and W. M. Watkins

Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain
Antimicrob. Agents Chemother. 1998 42: 164-169. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George G. Zhanel, Marilyn H. Saunders, Joyce N. Wolfe, Daryl J. Hoban, James A. Karlowsky, and Amin M. Kabani

Comparison of CO₂ Generation (BACTEC) and Viable-Count Methods To Determine the Postantibiotic Effect of Antimycobacterial Agents against Mycobacterium avium Complex
Antimicrob. Agents Chemother. 1998 42: 184-187. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia M. Roblin and Margaret R. Hammerschlag

Microbiologic Efficacy of Azithromycin and Susceptibilities to Azithromycin of Isolates of Chlamydia pneumoniae from Adults and Children with Community-Acquired Pneumonia
Antimicrob. Agents Chemother. 1998 42: 194-196. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Brenda McDougall, Peter J. King, Bor Wen Wu, Zdenek Hostomsky, Manfred G. Reinecke, and W. Edward Robinson, Jr.

Dicaffeoylquinic and Dicaffeoyltartaric Acids Are Selective Inhibitors of Human Immunodeficiency Virus Type 1 Integrase
Antimicrob. Agents Chemother. 1998 42: 140-146. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Johan Neyts and Erik De Clercq

In Vitro and In Vivo Inhibition of Murine Gamma Herpesvirus 68 Replication by Selected Antiviral Agents
Antimicrob. Agents Chemother. 1998 42: 170-172. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Asish Kumar Mukhopadhyay, Indira Basu, S. K. Bhattacharya, M. K. Bhattacharya, and G. Balakrish Nair

Emergence of Fluoroquinolone Resistance in Strains of Vibrio cholerae Isolated from Hospitalized Patients with Acute Diarrhea in Calcutta, India
Antimicrob. Agents Chemother. 1998 42: 206-207. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.