Contents: January 1998, Volume 42, Issue 1        Minireviews        Mechanisms of Action        Experimental Therapeutics        Clinical Therapeutics        Pharmacology        Mechanisms of Resistance        Susceptibility        Antiviral Agents        Letters Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

---

Minireviews:

---

Kinship and Diversification of Bacterial Penicillin-Binding Proteins and -Lactamases Irina Massova and Shahriar Mobashery Antimicrob. Agents Chemother. January 1998 42: 1-17; [Full Text] [PDF] [Reprints and Permissions]

---

Mechanisms of Action:

---

Atomic Force Microscopy: Application to Investigation of Escherichia coli Morphology before and after Exposure to Cefodizime Pier Carlo Braga and Davide Ricci Antimicrob. Agents Chemother. January 1998 42: 18-22; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Postantibiotic Effect in Escherichia coli Determined with Real-Time Metabolic Monitoring Jeffrey M. Libby Antimicrob. Agents Chemother. January 1998 42: 78-82; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II Heike Brötz, Gabriele Bierbaum, Klaus Leopold, Peter E. Reynolds, and Hans-Georg Sahl Antimicrob. Agents Chemother. January 1998 42: 154-160; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Sanfetrinem and Affinity for the Penicillin-Binding Proteins of Streptococcus pneumoniae Farid Sifaoui, Emmanuelle Varon, Marie-Dominique Kitzis, and Laurent Gutmann Antimicrob. Agents Chemother. January 1998 42: 173-175; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Experimental Therapeutics:

---

Efficacy of CS-834 against Experimental Pneumonia Caused by Penicillin-Susceptible and -Resistant Streptococcus pneumoniae in Mice Takashi Fukuoka, Harumi Kawada, Akiko Kitayama, Tetsufumi Koga, Mikie Kubota, Tamako Harasaki, Yasuki Kamai, Satoshi Ohya, Hiroshi Yasuda, Masayuki Iwata, and Shogo Kuwahara Antimicrob. Agents Chemother. January 1998 42: 23-27; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice Takahisa Furuta, Hideyuki Muramatsu, Akihiko Fujie, Shiro Fujihira, Noor Rain Abudullah, and Somei Kojima Antimicrob. Agents Chemother. January 1998 42: 37-39; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Long-Circulating Immunoliposomal Amphotericin B against Invasive Pulmonary Aspergillosis in Mice Takakazu Otsubo, Kazuo Maruyama, Shigefumi Maesaki, Yoshitsugu Miyazaki, Eitaro Tanaka, Tomoko Takizawa, Kunikazu Moribe, Kazunori Tomono, Takayoshi Tashiro, and Shigeru Kohno Antimicrob. Agents Chemother. January 1998 42: 40-44; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of the Efficacies of Three Fluoroquinolone Antimicrobial Agents, Given as Continuous or Pulsed-Water Medication, against Escherichia coli Infection in Chickens Bryan Charleston, John J. Gate, Ingrid A. Aitken, Bernd Stephan, and Robrecht Froyman Antimicrob. Agents Chemother. January 1998 42: 83-87; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

KY-62, a Polyene Analog of Amphotericin B, for Treatment of Murine Candidiasis John R. Graybill, Laura K. Najvar, Annette Fothergill, Thomas Hardin, Michael Rinaldi, Chris Lambros, and Steven L. Regen Antimicrob. Agents Chemother. January 1998 42: 147-150; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Treatment of Histoplasmosis with MK-991 (L-743,872) John R. Graybill, Laura K. Najvar, Eleanor M. Montalbo, Francesco J. Barchiesi, Michael F. Luther, and Michael G. Rinaldi Antimicrob. Agents Chemother. January 1998 42: 151-153; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence of Mycobacterium avium Populations Resistant to Macrolides during Experimental Chemotherapy Luiz E. Bermudez, Mary Petrofsky, Peter Kolonoski, and Lowell S. Young Antimicrob. Agents Chemother. January 1998 42: 180-183; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Treatment of Enterococcal Pyelonephritis with Trovafloxacin and Rifampin: In Vitro-In Vivo Contrast J. Z. Montgomerie and D. G. Schick Antimicrob. Agents Chemother. January 1998 42: 188-189; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Clinical Therapeutics:

---

Comparison of Strategies Using Cefpirome and Ceftazidime for Empiric Treatment of Pneumonia in Intensive Care Patients M. Wolff Antimicrob. Agents Chemother. January 1998 42: 28-36; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy and Safety of a 10-Day Course of 400 or 600 Milligrams of Grepafloxacin Once Daily for Treatment of Acute Bacterial Exacerbations of Chronic Bronchitis: Comparison with a 10-Day Course of 500 Milligrams of Ciprofloxacin Twice Daily S. Chodosh, S. Lakshminarayan, H. Swarz, and S. Breisch Antimicrob. Agents Chemother. January 1998 42: 114-120; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Randomized Comparison of Artemether-Benflumetol and Artesunate-Mefloquine in Treatment of MultidrugResistant Falciparum Malaria M. van Vugt, A. Brockman, B. Gemperli, C. Luxemburger, I. Gathmann, C. Royce, Thra Slight, S. Looareesuwan, N. J. White, and F. Nosten Antimicrob. Agents Chemother. January 1998 42: 135-139; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Pharmacology:

---

Antibacterial Efficacy against an In Vivo Salmonella typhimurium Infection Model and Pharmacokinetics of a Liposomal Ciprofloxacin Formulation Murray S. Webb, Nancy L. Boman, David J. Wiseman, Dawn Saxon, Kym Sutton, Kim F. Wong, Patricia Logan, and Michael J. Hope Antimicrob. Agents Chemother. January 1998 42: 45-52; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Trovafloxacin (with or without Ampicillin-Sulbactam) against Enterococci in an In Vitro Dynamic Model of Infection Stephen H. Zinner, Deborah Gilbert, and Michael N. Dudley Antimicrob. Agents Chemother. January 1998 42: 72-77; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Concentrations of Cefpirome in Cerebrospinal Fluid of Children with Bacterial Meningitis after a Single Intravenous Dose Ian R. Friedland, Eric Sultan, Karl H. Lehr, and Bernard Lenfant Antimicrob. Agents Chemother. January 1998 42: 199-201; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Mechanisms of Resistance:

---

Epidemiology and Successful Control of a Large Outbreak Due to Klebsiella pneumoniae Producing ExtendedSpectrum -Lactamases Carmen Peña, Miquel Pujol, Carmen Ardanuy, Asumpta Ricart, Roman Pallares, Josefina Liñares, Javier Ariza, and Francisco Gudiol Antimicrob. Agents Chemother. January 1998 42: 53-58; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Host Mutations (miaA and rpsL) Reduce Tetracycline Resistance Mediated by Tet(O) and Tet(M) Diane E. Taylor, Catharine A. Trieber, Gudrun Trescher, and Michelle Bekkering Antimicrob. Agents Chemother. January 1998 42: 59-64; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expression of Pseudomonas aeruginosa Multidrug Efflux Pumps MexA-MexB-OprM and MexC-MexD-OprJ in a Multidrug-Sensitive Escherichia coli Strain Ramakrishnan Srikumar, Tatiana Kon, Naomasa Gotoh, and Keith Poole Antimicrob. Agents Chemother. January 1998 42: 65-71; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Mutations Contributing to Sulfathiazole Resistance in Escherichia coli Gayatri Vedantam, Gordon G. Guay, Natasha E. Austria, Stella Z. Doktor, and Brian P. Nichols Antimicrob. Agents Chemother. January 1998 42: 88-93; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Decreased Susceptibilities to Teicoplanin and Vancomycin among Coagulase-Negative Methicillin-Resistant Clinical Isolates of Staphylococci Krzysztof Sieradzki, Paolo Villari, and Alexander Tomasz Antimicrob. Agents Chemother. January 1998 42: 100-107; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Novel Extended-Spectrum TEM-Type -Lactamase (TEM-52) Associated with Decreased Susceptibility to Moxalactam in Klebsiella pneumoniae Claire Poyart, Pierre Mugnier, Gilles Quesne, Patrick Berche, and Patrick Trieu-Cuot Antimicrob. Agents Chemother. January 1998 42: 108-113; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutations in Topoisomerase IV and DNA Gyrase of Staphylococcus aureus: Novel Pleiotropic Effects on Quinolone and Coumarin Activity Bénédicte Fournier and David C. Hooper Antimicrob. Agents Chemother. January 1998 42: 121-128; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sequences of Homologous -Lactamases from Clinical Isolates of Serratia marcescens with Different Substrate Specificities Naoki Matsumura, Shinzaburo Minami, and Susumu Mitsuhashi Antimicrob. Agents Chemother. January 1998 42: 176-179; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Nucleotide Sequence of the DNA Gyrase gyrA Gene from Serratia marcescens and Characterization of Mutations in gyrA of Quinolone-Resistant Clinical Isolates Jeong Hoon Kim, Eun Hee Cho, Kwang Seo Kim, Hak Yeop Kim, and Young Min Kim Antimicrob. Agents Chemother. January 1998 42: 190-193; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Topoisomerase Mutations in Fluoroquinolone-Resistant and Methicillin-Susceptible and -Resistant Clinical Isolates of Staphylococcus aureus Glenn W. Kaatz and Susan M. Seo Antimicrob. Agents Chemother. January 1998 42: 197-198; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA Sequence Variation within vanA, vanB, vanC-1, and vanC-2/3 Genes of Clinical Enterococcus Isolates Robin Patel, Jim R. Uhl, Peggy Kohner, Marlene K. Hopkins, James M. Steckelberg, Bruce Kline, and Franklin R. Cockerill, III Antimicrob. Agents Chemother. January 1998 42: 202-205; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Susceptibility:

---

In Vitro and In Vivo Antibacterial Activities of S-4661, a New Carbapenem Masakatsu Tsuji, Yoshikazu Ishii, Akira Ohno, Shuichi Miyazaki, and Keizo Yamaguchi Antimicrob. Agents Chemother. January 1998 42: 94-99; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Optimizing the Correlation between Results of Testing In Vitro and Therapeutic Outcome In Vivo for Fluconazole by Testing Critical Isolates in a Murine Model of Invasive Candidiasis John H. Rex, Page W. Nelson, Victor L. Paetznick, Mario Lozano-Chiu, A. Espinel-Ingroff, and Elias J. Anaissie Antimicrob. Agents Chemother. January 1998 42: 129-134; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Voriconazole (UK-109,496) and Four Other Antifungal Agents against 394 Clinical Isolates of Candida spp. F. Marco, M. A. Pfaller, S. Messer, and R. N. Jones Antimicrob. Agents Chemother. January 1998 42: 161-163; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain A. Nzila-Mounda, E. K. Mberu, C. H. Sibley, C. V. Plowe, P. A. Winstanley, and W. M. Watkins Antimicrob. Agents Chemother. January 1998 42: 164-169; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of CO2 Generation (BACTEC) and Viable-Count Methods To Determine the Postantibiotic Effect of Antimycobacterial Agents against Mycobacterium avium Complex George G. Zhanel, Marilyn H. Saunders, Joyce N. Wolfe, Daryl J. Hoban, James A. Karlowsky, and Amin M. Kabani Antimicrob. Agents Chemother. January 1998 42: 184-187; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Microbiologic Efficacy of Azithromycin and Susceptibilities to Azithromycin of Isolates of Chlamydia pneumoniae from Adults and Children with Community-Acquired Pneumonia Patricia M. Roblin and Margaret R. Hammerschlag Antimicrob. Agents Chemother. January 1998 42: 194-196; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Antiviral Agents:

---

Dicaffeoylquinic and Dicaffeoyltartaric Acids Are Selective Inhibitors of Human Immunodeficiency Virus Type 1 Integrase Brenda McDougall, Peter J. King, Bor Wen Wu, Zdenek Hostomsky, Manfred G. Reinecke, and W. Edward Robinson, Jr. Antimicrob. Agents Chemother. January 1998 42: 140-146; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Inhibition of Murine Gamma Herpesvirus 68 Replication by Selected Antiviral Agents Johan Neyts and Erik De Clercq Antimicrob. Agents Chemother. January 1998 42: 170-172; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Letters:

---

Emergence of Fluoroquinolone Resistance in Strains of Vibrio cholerae Isolated from Hospitalized Patients with Acute Diarrhea in Calcutta, India Asish Kumar Mukhopadhyay, Indira Basu, S. K. Bhattacharya, M. K. Bhattacharya, and G. Balakrish Nair Antimicrob. Agents Chemother. January 1998 42: 206-207; [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.