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Antiviral Agents:

Jim A. Turpin, Robert W. Buckheit, Jr., David Derse, Melinda Hollingshead, Karen Williamson, Carla Palamone, M. Clayton Osterling, Shawn A. Hill, Lisa Graham, Catherine A. Schaeffer, Ming Bu, Mingjun Huang, Wieslaw M. Cholody, Christopher J. Michejda, and William G. Rice

Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription
Antimicrob. Agents Chemother. 1998 42: 487-494. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian L. Robbins, Ranga V. Srinivas, Choung Kim, Norbert Bischofberger, and Arnold Fridland

Anti-Human Immunodeficiency Virus Activity and Cellular Metabolism of a Potential Prodrug of the Acyclic Nucleoside Phosphonate 9-R-(2-Phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA
Antimicrob. Agents Chemother. 1998 42: 612-617. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Witvrouw, M. E. Arranz, C. Pannecouque, R. Declercq, H. Jonckheere, J.-C. Schmit, A.-M. Vandamme, J. A. Diaz, S. T. Ingate, J. Desmyter, R. Esnouf, L. Van Meervelt, S. Vega, J. Balzarini, and E. De Clercq

1,1,3-Trioxo-2H,4H-Thieno[3,4-e][1,2,4]Thiadiazine (TTD) Derivatives: a New Class of Nonnucleoside Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitors with Anti-HIV-1 Activity
Antimicrob. Agents Chemother. 1998 42: 618-623. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dirk B. Mendel, Chun Y. Tai, Paul A. Escarpe, Weixing Li, Robert W. Sidwell, John H. Huffman, Clive Sweet, Kenneth J. Jakeman, James Merson, Steven A. Lacy, Willard Lew, Matthew A. Williams, Lijun Zhang, Ming S. Chen, Norbert Bischofberger, and Choung U. Kim

Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection
Antimicrob. Agents Chemother. 1998 42: 640-646. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Weixing Li, Paul A. Escarpe, Eugene J. Eisenberg, Kenneth C. Cundy, Clive Sweet, Kenneth J. Jakeman, James Merson, Willard Lew, Matt Williams, Lijun Zhang, Choung U. Kim, Norbert Bischofberger, Ming S. Chen, and Dirk B. Mendel

Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071
Antimicrob. Agents Chemother. 1998 42: 647-653. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Dianne B. Hoellman, Sheila K. Spangler, Michael R. Jacobs, and Peter C. Appelbaum

In Vitro Activities of Cefminox against Anaerobic Bacteria Compared with Those of Nine Other Compounds
Antimicrob. Agents Chemother. 1998 42: 495-501. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

O. Domarle, G. Blampain, H. Agnaniet, T. Nzadiyabi, J. Lebibi, J. Brocard, L. Maciejewski, C. Biot, A. J. Georges, and P. Millet

In Vitro Antimalarial Activity of a New Organometallic Analog, Ferrocene-Chloroquine
Antimicrob. Agents Chemother. 1998 42: 540-544. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael R. Jacobs, Ron Dagan, Peter C. Appelbaum, and Daniel J. Burch

Prevalence of Antimicrobial-Resistant Pathogens in Middle Ear Fluid: Multinational Study of 917 Children with Acute Otitis Media
Antimicrob. Agents Chemother. 1998 42: 589-595. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. A. Pankuch, M. A. Visalli, M. R. Jacobs, and P. C. Appelbaum

Susceptibilities of Penicillin- and Erythromycin-Susceptible and -Resistant Pneumococci to HMR 3647 (RU 66647), a New Ketolide, Compared with Susceptibilities to 17 Other Agents
Antimicrob. Agents Chemother. 1998 42: 624-630. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Koichi Izumikawa, Yoichi Hirakata, Toshiyuki Yamaguchi, Ryoji Yoshida, Hironori Tanaka, Hiromu Takemura, Shigefumi Maesaki, Kazunori Tomono, Mitsuo Kaku, Kin-Ichi Izumikawa, Shimeru Kamihira, and Shigeru Kohno

In Vitro Activities of Quinupristin-Dalfopristin and the Streptogramin RPR 106972 against Mycoplasma pneumoniae
Antimicrob. Agents Chemother. 1998 42: 698-699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kumiko Nagata, Kei-Ichi Hirai, Junko Koyama, Yasunao Wada, and Toshihide Tamura

Antimicrobial Activity of Novel Furanonaphthoquinone Analogs
Antimicrob. Agents Chemother. 1998 42: 700-702. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. M. Bébéar, H. Renaudin, A. Boudjadja, and C. Bébéar

In Vitro Activity of BAY 12-8039, a New Fluoroquinolone, against Mycoplasmas
Antimicrob. Agents Chemother. 1998 42: 703-704. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. John Rogers, Eric Cundliffe, and Thomas F. McCutchan

The Antibiotic Micrococcin Is a Potent Inhibitor of Growth and Protein Synthesis in the Malaria Parasite
Antimicrob. Agents Chemother. 1998 42: 715-716. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael J. Rybak, Diane M. Cappelletty, Tabitha Moldovan, Jeffrey R. Aeschlimann, and Glenn W. Kaatz

Comparative In Vitro Activities and Postantibiotic Effects of the Oxazolidinone Compounds Eperezolid (PNU-100592) and Linezolid (PNU-100766) versus Vancomycin against Staphylococcus aureus, Coagulase-Negative Staphylococci, Enterococcus faecalis, and Enterococcus faecium
Antimicrob. Agents Chemother. 1998 42: 721-724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Neil Woodford, Antoinette-Mary A. Adebiyi, Marie-France I. Palepou, and Barry D. Cookson

Diversity of VanA Glycopeptide Resistance Elements in Enterococci from Humans and Nonhuman Sources
Antimicrob. Agents Chemother. 1998 42: 502-508. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marek Gniadkowski, Ines Schneider, Renate Jungwirth, Waleria Hryniewicz, and Adolf Bauernfeind

Ceftazidime-Resistant Enterobacteriaceae Isolates from Three Polish Hospitals: Identification of Three Novel TEM- and SHV-5-Type Extended-Spectrum -Lactamases
Antimicrob. Agents Chemother. 1998 42: 514-520. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dominique Raze, Olivier Dardenne, Séverine Hallut, Manuel Martinez-Bueno, Jacques Coyette, and Jean-Marie Ghuysen

The Gene Encoding the Low-Affinity Penicillin-Binding Protein 3r in Enterococcus hirae S185R Is Borne on a Plasmid Carrying Other Antibiotic Resistance Determinants
Antimicrob. Agents Chemother. 1998 42: 534-539. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pierre E. Vaudaux, Vincenza Monzillo, Patrice Francois, Daniel P. Lew, Tim J. Foster, and Brigitte Berger-Bächi

Introduction of the mec Element (Methicillin Resistance) into Staphylococcus aureus Alters In Vitro Functional Activities of Fibrinogen and Fibronectin Adhesins
Antimicrob. Agents Chemother. 1998 42: 564-570. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masatoshi Tanaka, Tetsuro Matsumoto, Misao Sakumoto, Koichi Takahashi, Takeshi Saika, Intetsu Kabayashi, Joichi Kumazawa, and The Pazufloxacin Std Group

Reduced Clinical Efficacy of Pazufloxacin against Gonorrhea Due to High Prevalence of Quinolone-Resistant Isolates with the GyrA Mutation
Antimicrob. Agents Chemother. 1998 42: 579-582. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Johann D. D. Pitout, Kenneth S. Thomson, Nancy D. Hanson, Anton F. Ehrhardt, Philip Coudron, and Christine C. Sanders

Plasmid-Mediated Resistance to Expanded-Spectrum Cephalosporins among Enterobacter aerogenes Strains
Antimicrob. Agents Chemother. 1998 42: 596-600. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. A. Welton, L. A. Thal, M. B. Perri, S. Donabedian, J. McMahon, J. W. Chow, and M. J. Zervos

Antimicrobial Resistance in Enterococci Isolated from Turkey Flocks Fed Virginiamycin
Antimicrob. Agents Chemother. 1998 42: 705-708. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nobumichi Kobayashi, Koki Taniguchi, and Shozo Urasawa

Analysis of Diversity of Mutations in the mecI Gene and mecA Promoter/Operator Region of Methicillin-Resistant Staphylococcus aureus and Staphylococcus epidermidis
Antimicrob. Agents Chemother. 1998 42: 717-720. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Cornelius J. Clancy, Yue C. Yu, Alfred Lewin, and M. Hong Nguyen

Inhibition of RNA Synthesis as a Therapeutic Strategy against Aspergillus and Fusarium: Demonstration of In Vitro Synergy between Rifabutin and Amphotericin B
Antimicrob. Agents Chemother. 1998 42: 509-513. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lucia Carrano, Cecilia Bucci, Roberto De Pascalis, Alfredo Lavitola, Filomena Manna, Emiliana Corti, Carmelo Bruno Bruni, and Pietro Alifano

Effects of Bicyclomycin on RNA- and ATP-Binding Activities of Transcription Termination Factor Rho
Antimicrob. Agents Chemother. 1998 42: 571-578. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shaun R. Hawley, Patrick G. Bray, Mathirut Mungthin, Jill D. Atkinson, Paul M. O'Neill, and Stephen A. Ward

Relationship between Antimalarial Drug Activity, Accumulation, and Inhibition of Heme Polymerization in Plasmodium falciparum In Vitro
Antimicrob. Agents Chemother. 1998 42: 682-686. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jian-Ying Wang, Richard M. Burger, and Karl Drlica

Role of Superoxide in Catalase-Peroxidase-Mediated Isoniazid Action against Mycobacteria
Antimicrob. Agents Chemother. 1998 42: 709-711. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Jennifer K. Thomas, Alan Forrest, Sujata M. Bhavnani, Judith M. Hyatt, Angela Cheng, Charles H. Ballow, and Jerome J. Schentag

Pharmacodynamic Evaluation of Factors Associated with the Development of Bacterial Resistance in Acutely Ill Patients during Therapy
Antimicrob. Agents Chemother. 1998 42: 521-527. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard Hafner, James Bethel, Maureen Power, Bernard Landry, Mary Banach, Larry Mole, Harold C. Standiford, Stephen Follansbee, Princy Kumar, Ralph Raasch, David Cohn, David Mushatt, and George Drusano

Tolerance and Pharmacokinetic Interactions of Rifabutin and Clarithromycin in Human Immunodeficiency Virus-Infected Volunteers
Antimicrob. Agents Chemother. 1998 42: 631-639. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alexander A. Firsov, Alexander A. Shevchenko, Sergey N. Vostrov, and Stephen H. Zinner

Inter- and Intraquinolone Predictors of Antimicrobial Effect in an In Vitro Dynamic Model: New Insight into a Widely Used Concept
Antimicrob. Agents Chemother. 1998 42: 659-665. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kenneth C. Cundy, Cathy Sueoka, Geoffrey R. Lynch, Linda Griffin, William A. Lee, and Jeng-Pyng Shaw

Pharmacokinetics and Bioavailability of the Anti-Human Immunodeficiency Virus Nucleotide Analog 9-[(R)2-(Phosphonomethoxy)Propyl]Adenine (PMPA) in Dogs
Antimicrob. Agents Chemother. 1998 42: 687-690. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hirotami Matsuo, Miwako Ryu, Aya Nagata, Takahiro Uchida, Jun-Ichi Kawakami, Koujirou Yamamoto, Tatsuji Iga, and Yasufumi Sawada

Neurotoxicodynamics of the Interaction between Ciprofloxacin and Foscarnet in Mice
Antimicrob. Agents Chemother. 1998 42: 691-694. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric F. Trépanier, Anne N. Nafziger, and Guy W. Amsden

Effect of Terbinafine on Theophylline Pharmacokinetics in Healthy Volunteers
Antimicrob. Agents Chemother. 1998 42: 695-697. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

DeAnn M. Diamond, Madeline Bauer, Barbra E. Daniel, Mary Ann E. Leal, Debra Johnson, Byron K. Williams, Ann M. Thomas, James C. Ding, Laura Najvar, J. Richard Graybill, and Robert A. Larsen

Amphotericin B Colloidal Dispersion Combined with Flucytosine with or without Fluconazole for Treatment of Murine Cryptococcal Meningitis
Antimicrob. Agents Chemother. 1998 42: 528-533. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Douglas S. Kernodle, Hiriam Gates, and Allen B. Kaiser

Prophylactic Anti-Infective Activity of Poly-[1-6]--D-Glucopyranosyl-[1-3]--D-Glucopyranose Glucan in a Guinea Pig Model of Staphylococcal Wound Infection
Antimicrob. Agents Chemother. 1998 42: 545-549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Keizo Yamaguchi, Haruki Domon, Shuichi Miyazaki, Kazuhiro Tateda, Akira Ohno, Kazuhiro Ishii, Tetsuya Matsumoto, and Nobuhiko Furuya

In Vitro and In Vivo Antibacterial Activities of CS-834, a New Oral Carbapenem
Antimicrob. Agents Chemother. 1998 42: 555-563. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronald E. Blanton, Timothy M. Wachira, Eberhard E. Zeyhle, Ernest M. Njoroge, Japheth K. Magambo, and Peter M. Schantz

Oxfendazole Treatment for Cystic Hydatid Disease in Naturally Infected Animals
Antimicrob. Agents Chemother. 1998 42: 601-605. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yves Le Fichoux, Déborah Rousseau, Bernard Ferrua, Sandrine Ruette, Alain Lelièvre, Dominique Grousson, and Joanna Kubar

Short- and Long-Term Efficacy of Hexadecylphosphocholine against Established Leishmania infantum Infection in BALB/c Mice
Antimicrob. Agents Chemother. 1998 42: 654-658. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James Edwin Hall, John E. Kerrigan, Kishore Ramachandran, Brendan C. Bender, Jason P. Stanko, Susan K. Jones, Donald A. Patrick, and Richard R. Tidwell

Anti-Pneumocystis Activities of Aromatic Diamidoxime Prodrugs
Antimicrob. Agents Chemother. 1998 42: 666-674. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William R. Byrne, Susan L. Welkos, M. Louise Pitt, Kelly J. Davis, Ralf P. Brueckner, John W. Ezzell, Gene O. Nelson, Joseph R. Vaccaro, Luann C. Battersby, and Arthur M. Friedlander

Antibiotic Treatment of Experimental Pneumonic Plague in Mice
Antimicrob. Agents Chemother. 1998 42: 675-681. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lanfranco Fattorini, Yan Xiao, Maurizio Mattei, Yongjun Li, Elisabetta Iona, Maria Luisa Ricci, Ove Fredrik Thoresen, Roberta Creti, and Graziella Orefici

Activities of Isoniazid Alone and in Combination with Other Drugs against Mycobacterium avium Infection in Beige Mice
Antimicrob. Agents Chemother. 1998 42: 712-714. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

L. Tentori, G. Graziani, S. A. Porcelli, M. Sugita, M. B. Brenner, R. Madaio, E. Bonmassar, A. Giuliani, and A. Aquino

Rifampin Increases Cytokine-Induced Expression of the CD1b Molecule in Human Peripheral Blood Monocytes
Antimicrob. Agents Chemother. 1998 42: 550-554. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph J. Drabick, Apurba K. Bhattacharjee, David L. Hoover, George E. Siber, Vivian E. Morales, Lynnette D. Young, Scott L. Brown, and Alan S. Cross

Covalent Polymyxin B Conjugate with Human Immunoglobulin G as an Antiendotoxin Reagent
Antimicrob. Agents Chemother. 1998 42: 583-588. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Elias J. Anaissie, Gloria N. Mattiuzzi, Carole B. Miller, Gary A. Noskin, Marc J. Gurwith, Richard D. Mamelok, and Larry A. Pietrelli

Treatment of Invasive Fungal Infections in Renally Impaired Patients with Amphotericin B Colloidal Dispersion
Antimicrob. Agents Chemother. 1998 42: 606-611. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

G. von Recklinghausen, E. N. Schmid, A. Vollmer, and R. Ansorg

Morphological Effects of Miconazole on Helicobacter pylori
Antimicrob. Agents Chemother. 1998 42: 725-726. [Full Text] [PDF] [Reprints and Permissions]  

Martin E. Evans and William B. Titlow

Selection of Fluoroquinolone-Resistant Methicillin-Resistant Staphylococcus aureus with Ciprofloxacin and Trovafloxacin
Antimicrob. Agents Chemother. 1998 42: 727. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.