To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Clinical Therapeutics:

M. Zervos, M. Nelson, and the Cefepime Study Group

Cefepime versus Ceftriaxone for Empiric Treatment of Hospitalized Patients with Community-Acquired Pneumonia
Antimicrob. Agents Chemother. 1998 42: 729-733. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Cynthia R. Boschman, Ulana R. Bodnar, Michelle A. Tornatore, Arlene A. Obias, Gary A. Noskin, Kristin Englund, Michael A. Postelnick, Terra Suriano, and Lance R. Peterson

Thirteen-Year Evolution of Azole Resistance in Yeast Isolates and Prevalence of Resistant Strains Carried by Cancer Patients at a Large Medical Center
Antimicrob. Agents Chemother. 1998 42: 734-738. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Scott Walker, Sandra A. N. Tailor, Mark Lee, Lisa Louie, Marie Louie, and Andrew E. Simor

Amphotericin B in Lipid Emulsion: Stability, Compatibility, and In Vitro Antifungal Activity
Antimicrob. Agents Chemother. 1998 42: 762-766. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philippe Brasseur, Sophie Lecoublet, Nathalie Kapel, Loic Favennec, and Jean J. Ballet

In Vitro Evaluation of Drug Susceptibilities of Babesia divergens Isolates
Antimicrob. Agents Chemother. 1998 42: 818-820. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Margaret E. Perkins, Teresa W. Wu, and Sylvie M. Le Blancq

Cyclosporin Analogs Inhibit In Vitro Growth of Cryptosporidium parvum
Antimicrob. Agents Chemother. 1998 42: 843-848. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dianne B. Hoellman, Melissa A. Visalli, Michael R. Jacobs, and Peter C. Appelbaum

Activities and Time-Kill Studies of Selected Penicillins, -Lactamase Inhibitor Combinations, and Glycopeptides against Enterococcus faecalis
Antimicrob. Agents Chemother. 1998 42: 857-861. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wenqiu Liu, Xuejun Liu, David Knaebel, Linda Luck, and Yuzhou Li

Synthesis and Antibacterial Evaluation of Novel Water-Soluble Organic Peroxides
Antimicrob. Agents Chemother. 1998 42: 911-915. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria Souli and Helen Giamarellou

Effects of Slime Produced by Clinical Isolates of Coagulase-Negative Staphylococci on Activities of Various Antimicrobial Agents
Antimicrob. Agents Chemother. 1998 42: 939-941. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frederic Fitoussi, Catherine Doit, Karim Benali, Stephane Bonacorsi, Pierre Geslin, and Edouard Bingen

Comparative In Vitro Killing Activities of Meropenem, Imipenem, Ceftriaxone, and Ceftriaxone plus Vancomycin at Clinically Achievable Cerebrospinal Fluid Concentrations against Penicillin-Resistant Streptococcus pneumoniae Isolates from Children with Meningitis
Antimicrob. Agents Chemother. 1998 42: 942-944. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. L. Barry, P. C. Fuchs, and S. D. Brown

Antipneumococcal Activities of a Ketolide (HMR 3647), a Streptogramin (Quinupristin-Dalfopristin), a Macrolide (Erythromycin), and a Lincosamide (Clindamycin)
Antimicrob. Agents Chemother. 1998 42: 945-946. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia M. Roblin and Margaret R. Hammerschlag

In Vitro Activity of a New 8-Methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae
Antimicrob. Agents Chemother. 1998 42: 951-952. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melissa A. Visalli, Michael R. Jacobs, and Peter C. Appelbaum

Determination of Activities of Levofloxacin, Alone and Combined with Gentamicin, Ceftazidime, Cefpirome, and Meropenem, against 124 Strains of Pseudomonas aeruginosa by Checkerboard and Time-Kill Methodology
Antimicrob. Agents Chemother. 1998 42: 953-955. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jörg E. Hoppe and André Bryskier

In Vitro Susceptibilities of Bordetella pertussis and Bordetella parapertussis to Two Ketolides (HMR 3004 and HMR 3647), Four Macrolides (Azithromycin, Clarithromycin, Erythromycin A, and Roxithromycin), and Two Ansamycins (Rifampin and Rifapentine)
Antimicrob. Agents Chemother. 1998 42: 965-966. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard A. Hatch and Neal L. Schiller

Alginate Lyase Promotes Diffusion of Aminoglycosides through the Extracellular Polysaccharide of Mucoid Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 1998 42: 974-977. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stanley W. Chapman, P. David Rogers, Michael G. Rinaldi, and Donna C. Sullivan

Susceptibilities of Clinical and Laboratory Isolates of Blastomyces dermatitidis to Ketoconazole, Itraconazole, and Fluconazole
Antimicrob. Agents Chemother. 1998 42: 978-980. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hannah M. Wexler, Eric Molitoris, Denise Molitoris, and Sydney M. Finegold

In Vitro Activity of Levofloxacin against a Selected Group of Anaerobic Bacteria Isolated from Skin and Soft Tissue Infections
Antimicrob. Agents Chemother. 1998 42: 984-986. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Petra van Langevelde, Kitty M. C. Kwappenberg, Paul H. P. Groeneveld, Herman Mattie, and Jaap T. van Dissel

Antibiotic-Induced Lipopolysaccharide (LPS) Release from Salmonella typhi: Delay between Killing by Ceftazidime and Imipenem and Release of LPS
Antimicrob. Agents Chemother. 1998 42: 739-743. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jesse Paterson, Clara Uriel, Marie-Jose Egron, Jean Herscovici, Kostas Antonakis, and Moulay A. Alaoui-Jamali

Antiproliferative and Apoptotic Activities of Ketonucleosides and Keto-C-Glycosides against Non-Small-Cell Lung Cancer Cells with Intrinsic Drug Resistance
Antimicrob. Agents Chemother. 1998 42: 779-784. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kerstin J. Williams, Gavin A. C. Chung, and Laura J. V. Piddock

Accumulation of Norfloxacin by Mycobacterium aurum and Mycobacterium smegmatis
Antimicrob. Agents Chemother. 1998 42: 795-800. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Baodong Ling and Brigitte Berger-Bächi

Increased Overall Antibiotic Susceptibility in Staphylococcus aureus femAB Null Mutants
Antimicrob. Agents Chemother. 1998 42: 936-938. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Jan G. den Hollander, Johan W. Mouton, and Henri A. Verbrugh

Use of Pharmacodynamic Parameters To Predict Efficacy of Combination Therapy by Using Fractional Inhibitory Concentration Kinetics
Antimicrob. Agents Chemother. 1998 42: 744-748. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jan G. den Hollander, Kurt Fuursted, Henri A. Verbrugh, and Johan W. Mouton

Duration and Clinical Relevance of Postantibiotic Effect in Relation to the Dosing Interval
Antimicrob. Agents Chemother. 1998 42: 749-754. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michel Tod, Olivier Lortholary, Delphine Seytre, Rémi Semaoun, Bernard Uzzan, Loïc Guillevin, Philippe Casassus, and Olivier Petitjean

Population Pharmacokinetic Study of Amikacin Administered Once or Twice Daily to Febrile, Severely Neutropenic Adults
Antimicrob. Agents Chemother. 1998 42: 849-856. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shu-Chean Chien, Frank A. Wong, Cynthia L. Fowler, Susan V. Callery-D'Amico, R. Rex Williams, Ramchandra Nayak, and Andrew T. Chow

Double-Blind Evaluation of the Safety and Pharmacokinetics of Multiple Oral Once-Daily 750-Milligram and 1-Gram Doses of Levofloxacin in Healthy Volunteers
Antimicrob. Agents Chemother. 1998 42: 885-888. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. De Wit, E. O'Doherty, J. Edwards, R. Yates, R. P. Smith, and A. N. Clumeck

Pharmacokinetics of Two Multiple-Dosing Regimens of D0870 in Human Immunodeficiency Virus-Positive Patients: a Phase I Study
Antimicrob. Agents Chemother. 1998 42: 903-906. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kit L. Cheng, Anne N. Nafziger, Charles A. Peloquin, and Guy W. Amsden

Effect of Grapefruit Juice on Clarithromycin Pharmacokinetics
Antimicrob. Agents Chemother. 1998 42: 927-929. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bradley A. Boucher, Stephen R. King, Heidi L. Wandschneider, William L. Hickerson, Scott D. Hanes, Vanessa L. Herring, Todd W. Canada, and Mary M. Hess

Fluconazole Pharmacokinetics in Burn Patients
Antimicrob. Agents Chemother. 1998 42: 930-933. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Atsuko Ogawa, Takashi Hashida-Okado, Masahiro Endo, Hirofumi Yoshioka, Takashi Tsuruo, Kazutoh Takesako, and Ikunoshin Kato

Role of ABC Transporters in Aureobasidin A Resistance
Antimicrob. Agents Chemother. 1998 42: 755-761. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christine E. Swenson, Walter R. Perkins, Patricia Roberts, Imran Ahmad, Rachel Stevens, David A. Stevens, and Andrew S. Janoff

In Vitro and In Vivo Antifungal Activity of Amphotericin B Lipid Complex: Are Phospholipases Important?
Antimicrob. Agents Chemother. 1998 42: 767-771. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marek Gniadkowski, Ines Schneider, Renate Jungwirth, Barbara Mikiewicz, and Adolf Bauernfeind

Cefotaxime-Resistant Enterobacteriaceae Isolates from a Hospital in Warsaw, Poland: Identification of a New CTX-M-3 Cefotaxime-Hydrolyzing -Lactamase That Is Closely Related to the CTX-M-1/MEN-1 Enzyme
Antimicrob. Agents Chemother. 1998 42: 827-832. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Valérie Speldooren, Beate Heym, Roger Labia, and Marie-Hélène Nicolas-Chanoine

Discriminatory Detection of Inhibitor-Resistant -Lactamases in Escherichia coli by Single-Strand Conformation Polymorphism-PCR
Antimicrob. Agents Chemother. 1998 42: 879-884. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Silvia Schwank, Zarko Rajacic, Werner Zimmerli, and Jürg Blaser

Impact of Bacterial Biofilm Formation on In Vitro and In Vivo Activities of Antibiotics
Antimicrob. Agents Chemother. 1998 42: 895-898. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael W. Crowder, Timothy R. Walsh, Linda Banovic, Margaret Pettit, and James Spencer

Overexpression, Purification, and Characterization of the Cloned Metallo--Lactamase L1 from Stenotrophomonas maltophilia
Antimicrob. Agents Chemother. 1998 42: 921-926. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert W. Murray, Ronda D. Schaadt, Gary E. Zurenko, and Keith R. Marotti

Ribosomes from an Oxazolidinone-Resistant Mutant Confer Resistance to Eperezolid in a Staphylococcus aureus Cell-Free Transcription-Translation Assay
Antimicrob. Agents Chemother. 1998 42: 947-950. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xilin Zhao, Jian-Ying Wang, Chen Xu, Yuzhi Dong, Jianfeng Zhou, John Domagala, and Karl Drlica

Killing of Staphylococcus aureus by C-8-Methoxy Fluoroquinolones
Antimicrob. Agents Chemother. 1998 42: 956-958. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael R. Paradise, Gregory Cook, Robert K. Poole, and Philip N. Rather

Mutations in aarE, the ubiA Homolog of Providencia stuartii, Result in High-Level Aminoglycoside Resistance and Reduced Expression of the Chromosomal Aminoglycoside 2'-N-Acetyltransferase
Antimicrob. Agents Chemother. 1998 42: 959-962. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Louis B. Rice, Lenore L. Carias, Curtis L. Donskey, and Susan D. Rudin

Transferable, Plasmid-Mediated VanB-Type Glycopeptide Resistance in Enterococcus faecium
Antimicrob. Agents Chemother. 1998 42: 963-964. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Andrew Rutman, Ruth Dowling, Peter Wills, Charles Feldman, Peter J. Cole, and Robert Wilson

Effect of Dirithromycin on Haemophilus influenzae Infection of the Respiratory Mucosa
Antimicrob. Agents Chemother. 1998 42: 772-778. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Satoshi Yoshizumi, Haruki Domon, Shuichi Miyazaki, and Keizo Yamaguchi

In Vivo Activity of HSR-903, a New Fluoroquinolone, against Respiratory Pathogens
Antimicrob. Agents Chemother. 1998 42: 785-788. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl R. Beutner, Stephen K. Tyring, Kenneth F. Trofatter, Jr., John M. Douglas, Jr., Spotswood Spruance, Mary L. Owens, Terry L. Fox, Andrina J. Hougham, and Kathy A. Schmitt

Imiquimod, a Patient-Applied Immune-Response Modifier for Treatment of External Genital Warts
Antimicrob. Agents Chemother. 1998 42: 789-794. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gillian M. Smith, Brian Slocombe, Karen H. Abbott, and Linda W. Mizen

Activity of Amoxicillin-Clavulanate against Penicillin-Resistant Streptococcus pneumoniae in an Experimental Respiratory Infection Model in Rats
Antimicrob. Agents Chemother. 1998 42: 813-817. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David P. Nicolau, Lin Nie, Pamela R. Tessier, Helen P. Kourea, and Charles H. Nightingale

Prophylaxis of Acute Osteomyelitis with Absorbable Ofloxacin-Impregnated Beads
Antimicrob. Agents Chemother. 1998 42: 840-842. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean-Pierre Bédos, Véronique Rieux, Jacqueline Bauchet, Martine Muffat-Joly, Claude Carbon, and Esther Azoulay-Dupuis

Efficacy of Trovafloxacin against Penicillin-Susceptible and Multiresistant Strains of Streptococcus pneumoniae in a Mouse Pneumonia Model
Antimicrob. Agents Chemother. 1998 42: 862-867. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paul E. Verweij, Karen L. Oakley, Jacqui Morrissey, Graham Morrissey, and David W. Denning

Efficacy of LY303366 against Amphotericin B-Susceptible and -Resistant Aspergillus fumigatus in a Murine Model of Invasive Aspergillosis
Antimicrob. Agents Chemother. 1998 42: 873-878. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl V. Clemons and David A. Stevens

Comparison of Fungizone, Amphotec, AmBisome, and Abelcet for Treatment of Systemic Murine Cryptococcosis
Antimicrob. Agents Chemother. 1998 42: 899-902. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marilyn S. Bartlett, Margaret M. Shaw, James W. Smith, and Steven R. Meshnick

Efficacy of Sulfamethoxypyridazine in a Murine Model of Pneumocystis carinii Pneumonia
Antimicrob. Agents Chemother. 1998 42: 934-935. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshimi Niwano, Naoki Kuzuhara, Hiroki Kodama, Masanori Yoshida, Tsuneo Miyazaki, and Hideyo Yamaguchi

In Vitro and In Vivo Antidermatophyte Activities of NND-502, a Novel Optically Active Imidazole Antimycotic Agent
Antimicrob. Agents Chemother. 1998 42: 967-970. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Glenn W. Kaatz, Susan M. Seo, Jeffrey R. Aeschlimann, Heather H. Houlihan, Renee-Claude Mercier, and Michael J. Rybak

Efficacy of LY333328 against Experimental Methicillin-Resistant Staphylococcus aureus Endocarditis
Antimicrob. Agents Chemother. 1998 42: 981-983. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Shanta Bantia, Anita A. Ghate, Sandya L. Ananth, Y. Sudhakar Babu, Gillian M. Air, and Gerald M. Walsh

Generation and Characterization of a Mutant of Influenza A Virus Selected with the Neuraminidase Inhibitor BCX-140
Antimicrob. Agents Chemother. 1998 42: 801-807. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark Mirochnick, Edmund Capparelli, Wayne Dankner, Rhoda S. Sperling, Russ van Dyke, and Stephen A. Spector

Zidovudine Pharmacokinetics in Premature Infants Exposed to Human Immunodeficiency Virus
Antimicrob. Agents Chemother. 1998 42: 808-812. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Adams, Mark J. Shelton, Ross G. Hewitt, Thaddeus H. Grasela, Mary DeRemer, and Gene D. Morse

Relationship between Didanosine Exposure and Surrogate Marker Response in Human Immunodeficiency Virus-Infected Outpatients
Antimicrob. Agents Chemother. 1998 42: 821-826. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shwu-Huey Liu, Kristie L. Grove, and Yung-Chi Cheng

Unique Metabolism of a Novel Antiviral L-Nucleoside Analog, 2'-Fluoro-5-Methyl--L-Arabinofuranosyluracil: a Substrate for Both Thymidine Kinase and Deoxycytidine Kinase
Antimicrob. Agents Chemother. 1998 42: 833-839. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jacqueline Christophers, Julie Clayton, John Craske, Rosemary Ward, Peter Collins, Martin Trowbridge, and Graham Darby

Survey of Resistance of Herpes Simplex Virus to Acyclovir in Northwest England
Antimicrob. Agents Chemother. 1998 42: 868-872. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Q. May Wang, Robert B. Johnson, Louis N. Jungheim, Jeffrey D. Cohen, and Elcira C. Villarreal

Dual Inhibition of Human Rhinovirus 2A and 3C Proteases by Homophthalimides
Antimicrob. Agents Chemother. 1998 42: 916-920. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gilbert B. Mulamba, André Hu, Raana F. Azad, Kevin P. Anderson, and Donald M. Coen

Human Cytomegalovirus Mutant with Sequence-Dependent Resistance to the Phosphorothioate Oligonucleotide Fomivirsen (ISIS 2922)
Antimicrob. Agents Chemother. 1998 42: 971-973. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

Timothy R. Hammonds, Anthony Maxwell, and John R. Jenkins

Use of a Rapid Throughput In Vivo Screen To Investigate Inhibitors of Eukaryotic Topoisomerase II Enzymes
Antimicrob. Agents Chemother. 1998 42: 889-894. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Shefali Vora, Nayanatara Purimetla, Elmer Brummer, and David A. Stevens

Activity of Voriconazole, a New Triazole, Combined with Neutrophils or Monocytes against Candida albicans: Effect of Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor
Antimicrob. Agents Chemother. 1998 42: 907-910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Recent Approvals:

New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 1997 and New Indications for Previously Approved Agents
Antimicrob. Agents Chemother. 1998 42: 987-988. [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Isabel Garcia-Bermejo, Juana Cacho, Beatriz Orden, Juan-Ignacio Alós, and Jose-Luis Gómez-Garcés

Emergence of Erythromycin-Resistant, Clindamycin-Susceptible Streptococcus pyogenes Isolates in Madrid, Spain
Antimicrob. Agents Chemother. 1998 42: 989-990. [Full Text] [PDF] [Reprints and Permissions]  

David P. Nicolau, Pamela R. Tessier, Richard Quintiliani, and Charles H. Nightingale

Synergistic Activity of Trovafloxacin and Ceftriaxone or Vancomycin against Streptococcus pneumoniae with Various Penicillin Susceptibilities
Antimicrob. Agents Chemother. 1998 42: 991-992. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Joan C. Fung-Tomc, Elizabeth Huczko, Beatrice Minassian, and Daniel P. Bonner

In Vitro Activity of a New Oral Triazole, BMS-207147 (ER-30346)
Antimicrob. Agents Chemother. 1998 42: 993. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.