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Minireviews:

Louis B. Rice

Tn916 Family Conjugative Transposons and Dissemination of Antimicrobial Resistance Determinants
Antimicrob. Agents Chemother. 1998 42: 1871-1877. [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Shawn M. Cassidy, Frank W. Strobel, and Kishor M. Wasan

Plasma Lipoprotein Distribution of Liposomal Nystatin Is Influenced by Protein Content of High-Density Lipoproteins
Antimicrob. Agents Chemother. 1998 42: 1878-1888. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Vazifeh, A. Preira, A. Bryskier, and M. T. Labro

Interactions between HMR 3647, a New Ketolide, and Human Polymorphonuclear Neutrophils
Antimicrob. Agents Chemother. 1998 42: 1944-1951. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Charles J. Gill, Jesse J. Jackson, Lynn S. Gerckens, Barbara A. Pelak, Randall K. Thompson, Jon G. Sundelof, Helmut Kropp, and H. Rosen

In Vivo Activity and Pharmacokinetic Evaluation of a Novel Long-Acting Carbapenem Antibiotic, MK-826 (L-749,345)
Antimicrob. Agents Chemother. 1998 42: 1996-2001. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Roland Nau, Christoph Lassek, Martina Kinzig-Schippers, Andreas Thiel, Hilmar W. Prange, and Fritz Sörgel

Disposition and Elimination of Meropenem in Cerebrospinal Fluid of Hydrocephalic Patients with External Ventriculostomy
Antimicrob. Agents Chemother. 1998 42: 2012-2016. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Giorgio Gatti, Pietro Papa, Donato Torre, Massimo Andreoni, Antonio Poggio, Matteo Bassetti, and Piero Marone

Population Pharmacokinetics of Rifabutin in Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 1998 42: 2017-2023. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alan J. Fischman, John W. Babich, Ali A. Bonab, Nathaniel M. Alpert, John Vincent, Ronald J. Callahan, John A. Correia, and Robert H. Rubin

Pharmacokinetics of [¹⁸F]Trovafloxacin in Healthy Human Subjects Studied with Positron Emission Tomography
Antimicrob. Agents Chemother. 1998 42: 2048-2054. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. Stass, A. Dalhoff, D. Kubitza, and U. Schühly

Pharmacokinetics, Safety, and Tolerability of Ascending Single Doses of Moxifloxacin, a New 8-Methoxy Quinolone, Administered to Healthy Subjects
Antimicrob. Agents Chemother. 1998 42: 2060-2065. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

J. M. Entenza, O. Marchetti, M. P. Glauser, and P. Moreillon

Y-688, a New Quinolone Active against Quinolone-Resistant Staphylococcus aureus: Lack of In Vivo Efficacy in Experimental Endocarditis
Antimicrob. Agents Chemother. 1998 42: 1889-1894. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George S. Baillie and L. Julia Douglas

Effect of Growth Rate on Resistance of Candida albicans Biofilms to Antifungal Agents
Antimicrob. Agents Chemother. 1998 42: 1900-1905. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hideyuki Fukuda, Satoshi Hori, and Keiichi Hiramatsu

Antibacterial Activity of Gatifloxacin (AM-1155, CG5501, BMS-206584), a Newly Developed Fluoroquinolone, against Sequentially Acquired Quinolone-Resistant Mutants and the norA Transformant of Staphylococcus aureus
Antimicrob. Agents Chemother. 1998 42: 1917-1922. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edda De Rossi, Marian C. J. Blokpoel, Rita Cantoni, Manuela Branzoni, Giovanna Riccardi, Douglas B. Young, Koen A. L. De Smet, and Orio Ciferri

Molecular Cloning and Functional Analysis of a Novel Tetracycline Resistance Determinant, tet(V), from Mycobacterium smegmatis
Antimicrob. Agents Chemother. 1998 42: 1931-1937. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naomasa Gotoh, Hideto Tsujimoto, Masataka Tsuda, Kiyomi Okamoto, Atsuko Nomura, Takaomi Wada, Masaaki Nakahashi, and Takeshi Nishino

Characterization of the MexC-MexD-OprJ Multidrug Efflux System in mexA-mexB-oprM Mutants of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 1998 42: 1938-1943. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ge Wang and Diane E. Taylor

Site-Specific Mutations in the 23S rRNA Gene of Helicobacter pylori Confer Two Types of Resistance to Macrolide-Lincosamide-Streptogramin B Antibiotics
Antimicrob. Agents Chemother. 1998 42: 1952-1958. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

François Sanschagrin, Noureddine Bejaoui, and Roger C. Levesque

Structure of CARB-4 and AER-1 CarbenicillinHydrolyzing -Lactamases
Antimicrob. Agents Chemother. 1998 42: 1966-1972. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia A. Bradford, Youjun Yang, Daniel Sahm, Ilze Grope, Dace Gardovska, and Gregory Storch

CTX-M-5, a Novel Cefotaxime-Hydrolyzing -Lactamase from an Outbreak of Salmonella typhimurium in Latvia
Antimicrob. Agents Chemother. 1998 42: 1980-1984. [Abstract] [Full Text] [Reprints and Permissions]  

Armando Lucumi, Sara Robledo, Vivian Gama, and Nancy G. Saravia

Sensitivity of Leishmania viannia panamensis to Pentavalent Antimony Is Correlated with the Formation of Cleavable DNA-Protein Complexes
Antimicrob. Agents Chemother. 1998 42: 1990-1995. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoichi Hirakata, Koichi Izumikawa, Toshiyuki Yamaguchi, Hiromu Takemura, Hironori Tanaka, Ryoji Yoshida, Junichi Matsuda, Michiko Nakano, Kazunori Tomono, Shigefumi Maesaki, Mitsuo Kaku, Yasuaki Yamada, Shimeru Kamihira, and Shigeru Kohno

Rapid Detection and Evaluation of Clinical Characteristics of Emerging Multiple-Drug-Resistant Gram-Negative Rods Carrying the Metallo--Lactamase Gene bla_IMP
Antimicrob. Agents Chemother. 1998 42: 2006-2011. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cécile M. Bébéar, Alain Charron, Joseph Marie Bové, Christiane Bébéar, and Joel Renaudin

Cloning and Nucleotide Sequences of the Topoisomerase IV parC and parE Genes of Mycoplasma hominis
Antimicrob. Agents Chemother. 1998 42: 2024-2031. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nigel P. Brenwald, Martin J. Gill, and Richard Wise

Prevalence of a Putative Efflux Mechanism among Fluoroquinolone-Resistant Clinical Isolates of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 1998 42: 2032-2035. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marco Ligozzi, Giuliana Lo Cascio, and Roberta Fontana

vanA Gene Cluster in a Vancomycin-Resistant Clinical Isolate of Bacillus circulans
Antimicrob. Agents Chemother. 1998 42: 2055-2059. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Naas, Wladimir Sougakoff, Anne Casetta, and Patrice Nordmann

Molecular Characterization of OXA-20, a Novel Class D -Lactamase, and Its Integron from Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 1998 42: 2074-2083. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Isabelle Guillemin, Vincent Jarlier, and Emmanuelle Cambau

Correlation between Quinolone Susceptibility Patterns and Sequences in the A and B Subunits of DNA Gyrase in Mycobacteria
Antimicrob. Agents Chemother. 1998 42: 2084-2088. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Margret Oethinger, Isabelle Podglajen, Winfried V. Kern, and Stuart B. Levy

Overexpression of the marA or soxS Regulatory Gene in Clinical Topoisomerase Mutants of Escherichia coli
Antimicrob. Agents Chemother. 1998 42: 2089-2094. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David L. Trees, Amy L. Sandul, William L. Whittington, and Joan S. Knapp

Identification of Novel Mutation Patterns in the parC Gene of Ciprofloxacin-Resistant Isolates of Neisseria gonorrhoeae
Antimicrob. Agents Chemother. 1998 42: 2103-2105. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bénédicte Fournier and David C. Hooper

Effects of Mutations in GrlA of Topoisomerase IV from Staphylococcus aureus on Quinolone and Coumarin Activity
Antimicrob. Agents Chemother. 1998 42: 2109-2112. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Corinna Kehrenberg, Christiane Werckenthin, and Stefan Schwarz

Tn5706, a Transposon-Like Element from Pasteurella multocida Mediating Tetracycline Resistance
Antimicrob. Agents Chemother. 1998 42: 2116-2118. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shin Miyamae, Hiroshi Nikaido, Yoshinobu Tanaka, and Fuminobu Yoshimura

Active Efflux of Norfloxacin by Bacteroides fragilis
Antimicrob. Agents Chemother. 1998 42: 2119-2121. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph E. Fitzgibbon, Joseph F. John, Jennifer L. Delucia, and Donald T. Dubin

Topoisomerase Mutations in Trovafloxacin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 1998 42: 2122-2124. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Tessier, C. Arpin, A. Allery, and C. Quentin

Molecular Characterization of a TEM-21 -Lactamase in a Clinical Isolate of Morganella morganii
Antimicrob. Agents Chemother. 1998 42: 2125-2127. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dolena R. Ledee, David V. Seal, and Thomas J. Byers

Confirmatory Evidence from 18S rRNA Gene Analysis for In Vivo Development of Propamidine Resistance in a Temporal Series of Acanthamoeba Ocular Isolates from a Patient
Antimicrob. Agents Chemother. 1998 42: 2144-2145. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Shunji Hayashi, Toshiro Sugiyama, Ken-Ichi Amano, Hiroshi Isogai, Emiko Isogai, Miki Aihara, Mikio Kikuchi, Masahiro Asaka, Kenji Yokota, Keiji Oguma, Nobuhiro Fujii, and Yoshikazu Hirai

Effect of Rebamipide, a Novel Antiulcer Agent, on Helicobacter pylori Adhesion to Gastric Epithelial Cells
Antimicrob. Agents Chemother. 1998 42: 1895-1899. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anja Lührmann, Jürgen Thölke, Ingrid Behn, Jens Schumann, Gisa Tiegs, and Sunna Hauschildt

Immunomodulating Properties of the Antibiotic Novobiocin in Human Monocytes
Antimicrob. Agents Chemother. 1998 42: 1911-1916. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kristian Riesbeck, Arne Forsgren, Agnethe Henriksson, and Anders Bredberg

Ciprofloxacin Induces an Immunomodulatory Stress Response in Human T Lymphocytes
Antimicrob. Agents Chemother. 1998 42: 1923-1930. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

Vuokko Loimaranta, Jorma Tenovuo, Leeni Koivisto, and Matti Karp

Generation of Bioluminescent Streptococcus mutans and Its Usage in Rapid Analysis of the Efficacy of Antimicrobial Compounds
Antimicrob. Agents Chemother. 1998 42: 1906-1910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Cynthia M. Theodos, Jeffrey K. Griffiths, Jennifer D'Onfro, Alexandra Fairfield, and Saul Tzipori

Efficacy of Nitazoxanide against Cryptosporidium parvum in Cell Culture and in Animal Models
Antimicrob. Agents Chemother. 1998 42: 1959-1965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mary Ann Powles, Paul Liberator, Jennifer Anderson, Yashwant Karkhanis, James F. Dropinski, F. Aileen Bouffard, James M. Balkovec, Hisashi Fujioka, Masamichi Aikawa, Diane McFadden, and Dennis Schmatz

Efficacy of MK-991 (L-743,872), a Semisynthetic Pneumocandin, in Murine Models of Pneumocystis carinii
Antimicrob. Agents Chemother. 1998 42: 1985-1989. [Abstract] [Full Text] [Reprints and Permissions]  

Baohong Ji, Nacer Lounis, Caroline Maslo, Chantal Truffot-Pernot, Pascale Bonnafous, and Jacques Grosset

In Vitro and In Vivo Activities of Moxifloxacin and Clinafloxacin against Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 1998 42: 2066-2069. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Christine E. Thorburn, Sarah J. Knott, and David I. Edwards

In Vitro Activities of Oral -Lactams at Concentrations Achieved in Humans against Penicillin-Susceptible and -Resistant Pneumococci and Potential to Select Resistance
Antimicrob. Agents Chemother. 1998 42: 1973-1979. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melissa A. Visalli, Michael R. Jacobs, and Peter C. Appelbaum

Activities of Three Quinolones, Alone and in Combination with Extended-Spectrum Cephalosporins or Gentamicin, against Stenotrophomonas maltophilia
Antimicrob. Agents Chemother. 1998 42: 2002-2005. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Portaels, H. Traore, K. De Ridder, and W. M. Meyers

In Vitro Susceptibility of Mycobacterium ulcerans to Clarithromycin
Antimicrob. Agents Chemother. 1998 42: 2070-2073. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christiane Gaudreau and Huguette Gilbert

Antimicrobial Resistance of Clinical Strains of Campylobacter jejuni subsp. jejuni Isolated from 1985 to 1997 in Quebec, Canada
Antimicrob. Agents Chemother. 1998 42: 2106-2108. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arthur L. Barry, Peter C. Fuchs, and Steven D. Brown

In Vitro Activities of the Ketolide HMR 3647 against Recent Gram-Positive Clinical Isolates and Haemophilus influenzae
Antimicrob. Agents Chemother. 1998 42: 2138-2140. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George S. Baillie and L. Julia Douglas

Iron-Limited Biofilms of Candida albicans and Their Susceptibility to Amphotericin B
Antimicrob. Agents Chemother. 1998 42: 2146-2149. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Randee Estes, Nicolas Vogel, Douglas Mack, and Rima McLeod

Paclitaxel Arrests Growth of Intracellular Toxoplasma gondii
Antimicrob. Agents Chemother. 1998 42: 2036-2040. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Yoshiko Hosoya, Susumu Okamoto, Hideyuki Muramatsu, and Kozo Ochi

Acquisition of Certain Streptomycin-Resistant (str) Mutations Enhances Antibiotic Production in Bacteria
Antimicrob. Agents Chemother. 1998 42: 2041-2047. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Nobukazu Ono, Satoshi Iwayama, Katsuya Suzuki, Takaaki Sekiyama, Harumi Nakazawa, Takashi Tsuji, Masahiko Okunishi, Tohru Daikoku, and Yukihiro Nishiyama

Mode of Action of (1'S,2'R)-9-{[1',2'-Bis(hydroxymethyl) cycloprop-1'-yl]methyl}guanine (A-5021) against Herpes Simplex Virus Type 1 and Type 2 and Varicella-Zoster Virus
Antimicrob. Agents Chemother. 1998 42: 2095-2102. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cheryl A. Stoddart, Linda Rabin, Mara Hincenbergs, Mary e. Moreno, Valerie Linquist-Stepps, Janet M. Leeds, Lo Anne Truong, J. R. Wyatt, David J. Ecker, and Joseph M. McCune

Inhibition of Human Immunodeficiency Virus Type 1 Infection in SCID-hu Thy/Liv Mice by the G-Quartet-Forming Oligonucleotide, ISIS 5320
Antimicrob. Agents Chemother. 1998 42: 2113-2115. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephanie K. Ladner, Thomas J. Miller, and Robert W. King

The M539V Polymerase Variant of Human Hepatitis B Virus Demonstrates Resistance to 2'-Deoxy-3'-Thiacytidine and a Reduced Ability to Synthesize Viral DNA
Antimicrob. Agents Chemother. 1998 42: 2128-2131. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Enjarn Lin, Carolyn Luscombe, Danni Colledge, Yan Yan Wang, and Stephen Locarnini

Long-Term Therapy with the Guanine Nucleoside Analog Penciclovir Controls Chronic Duck Hepatitis B Virus Infection In Vivo
Antimicrob. Agents Chemother. 1998 42: 2132-2137. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Remy Durand, Muriel Paul, Francine Pratlong, Daniele Rivollet, Marie-Laure Dubreuil-Lemaire, Rene Houin, Alain Astier, and Michele Deniau

Leishmania infantum: Lack of Parasite Resistance to Amphotericin B in a Clinically Resistant Visceral Leishmaniasis
Antimicrob. Agents Chemother. 1998 42: 2141-2143. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Naohisa Fujita, Manabu Yoshimura, Toshiaki Komori, Koichi Tanimoto, and Yasuyoshi Ike

First Report of the Isolation of High-Level Vancomycin-Resistant Enterococcus faecium from a Patient in Japan
Antimicrob. Agents Chemother. 1998 42: 2150. [Full Text] [PDF] [Reprints and Permissions]  

A. D. Russell, Unchalee Tattawasart, J.-Y. Maillard, and J. R. Furr

Possible Link between Bacterial Resistance and Use of Antibiotics and Biocides
Antimicrob. Agents Chemother. 1998 42: 2151. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Shefali Vora, Nayanatara Purimetla, Elmer Brummer, and David A. Stevens

Activity of Voriconazole, a New Triazole, Combined with Neutrophils or Monocytes against Candida albicans: Effect of Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor
Antimicrob. Agents Chemother. 1998 42: 2152. [Full Text] [PDF] [Reprints and Permissions]  

Frederic Fitoussi, Catherine Doit, Karim Benali, Stephane Bonacorsi, Pierre Geslin, and Edouard Bingen

Comparative In Vitro Killing Activities of Meropenem, Imipenem, Ceftriaxone, and Ceftriaxone plus Vancomycin at Clinically Achievable Cerebrospinal Fluid Concentrations against Penicillin-Resistant Streptococcus pneumoniae Isolates from Children with Meningitis
Antimicrob. Agents Chemother. 1998 42: 2152. [Full Text] [PDF] [Reprints and Permissions]  

New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 1997 and New Indications for Previously Approved Agents
Antimicrob. Agents Chemother. 1998 42: 2152. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.