Contents: January 1999, Volume 43, Issue 1        Minireviews        Pharmacology        Clinical Therapeutics        Susceptibility        Mechanisms of Resistance        Antiviral Agents        Experimental Therapeutics        Chemistry; Biosynthesis        Mechanisms of Action        Letters        Errata Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Antifungal Peptides: Novel Therapeutic Compounds against Emerging Pathogens Anthony J. De Lucca and Thomas J. Walsh Antimicrob. Agents Chemother. January 1999 43: 1-11; [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Uptake and Intracellular Activity of Moxifloxacin in Human Neutrophils and Tissue-Cultured Epithelial Cells Alvaro Pascual, Isabel García, Sofía Ballesta, and Evelio J. Perea Antimicrob. Agents Chemother. January 1999 43: 12-15; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Close Association between Clearance of Recombinant Human Granulocyte Colony-Stimulating Factor (G-CSF) and G-CSF Receptor on Neutrophils in Cancer Patients Kenji Terashi, Mikio Oka, Shigehiro Ohdo, Taku Furukubo, Chizuko Ikeda, Minoru Fukuda, Hiroshi Soda, Shun Higuchi, and Shigeru Kohno Antimicrob. Agents Chemother. January 1999 43: 21-24; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Two Pharmacodynamic Models for Assessing the Efficacy of Amoxicillin-Clavulanate against Experimental Respiratory Tract Infections Caused by Strains of Streptococcus pneumoniae Gary Woodnutt and Valerie Berry Antimicrob. Agents Chemother. January 1999 43: 29-34; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of High-Dose Amoxicillin-Clavulanate against Experimental Respiratory Tract Infections Caused by Strains of Streptococcus pneumoniae Gary Woodnutt and Valerie Berry Antimicrob. Agents Chemother. January 1999 43: 35-40; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Probenecid on the Renal Excretion Mechanism of a New Carbapenem, DA-1131, in Rats and Rabbits So H. Kim, Won B. Kim, and Myung G. Lee Antimicrob. Agents Chemother. January 1999 43: 96-99; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evaluation of Several Dosing Regimens of Cefepime, with Various Simulations of Renal Function, against Clinical Isolates of Pseudomonas aeruginosa in a Pharmacodynamic Infection Model Diane M. Cappelletty Antimicrob. Agents Chemother. January 1999 43: 129-133; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Limited-Sampling Strategy Models for Itraconazole and Hydroxy-Itraconazole Based on Data from a Bioequivalence Study Guilherme Suarez-Kurtz, Fernando A. Bozza, Flavio L. Vicente, Cristiano G. Ponte, and Claudio J. Struchiner Antimicrob. Agents Chemother. January 1999 43: 134-140; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Penetration of Oral Fluconazole into Gynecological Tissues Hiroshige Mikamo, Kyoko Kawazoe, Yasumasa Sato, Koji Izumi, Toshiya Ito, Kunihiko Ito, and Teruhiko Tamaya Antimicrob. Agents Chemother. January 1999 43: 148-151; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Quinupristin-Dalfopristin in Continuous Ambulatory Peritoneal Dialysis Patients Curtis A. Johnson, Claude A. Taylor, III, Stephen W. Zimmerman, William E. Bridson, Paul Chevalier, Olivier Pasquier, and Robert I. Baybutt Antimicrob. Agents Chemother. January 1999 43: 152-156; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics in Serum and Leukocyte Exposures of Oral Azithromycin, 1,500 Milligrams, Given over a 3- or 5-Day Period in Healthy Subjects Guy W. Amsden, Anne N. Nafziger, and George Foulds Antimicrob. Agents Chemother. January 1999 43: 163-165; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Eradication by Ceftriaxone of Streptococcus pneumoniae Isolates with Increased Resistance to Penicillin in Cases of Acute Otitis Media P. Gehanno, L. Nguyen, B. Barry, M. Derriennic, F. Pichon, J. M. Goehrs, and P. Berche Antimicrob. Agents Chemother. January 1999 43: 16-20; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Development of Rifapentine Susceptibility Tests for Mycobacterium tuberculosis L. Heifets, T. Sanchez, J. Vanderkolk, and V. Pham Antimicrob. Agents Chemother. January 1999 43: 25-28; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of New 5-Nitroimidazoles against Metronidazole-Susceptible and -Resistant Giardia, Trichomonas, and Entamoeba spp. Jacqueline A. Upcroft, Raymond W. Campbell, Kamel Benakli, Peter Upcroft, and Patrice Vanelle Antimicrob. Agents Chemother. January 1999 43: 73-76; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Acetate-Mediated Growth Inhibition in Sterol 14-Demethylation-Deficient Cells of Candida albicans Osamu Shimokawa and Hiroaki Nakayama Antimicrob. Agents Chemother. January 1999 43: 100-105; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of HMR 3647 Compared to Those of Six Compounds against 235 Strains of Enterococcus faecalis Dianne B. Hoellman, Gengrong Lin, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. January 1999 43: 166-168; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Voriconazole, Fluconazole, and Itraconazole against 566 Clinical Isolates of Cryptococcus neoformans from the United States and Africa M. A. Pfaller, J. Zhang, S. A. Messer, M. E. Brandt, R. A. Hajjeh, C. J. Jessup, M. Tumberland, E. K. Mbidde, and M. A. Ghannoum Antimicrob. Agents Chemother. January 1999 43: 169-171; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Resistance of 914 Beta-Hemolytic Streptococci Isolated from Pharyngeal Swabs in Spain: Results of a 1-Year (1996-1997) Multicenter Surveillance Study Fernando Baquero, José Angel García-Rodríguez, Juan García de Lomas, Lorenzo Aguilar, and the Spanish Surveillance Group for Respiratory Pathogens Antimicrob. Agents Chemother. January 1999 43: 178-180; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A 5-Year Surveillance Study of 44,691 Isolates of Haemophilus influenzae Project Beta-Alert 1993-1997 A. Derecola, D. L. Butler, R. L. Kaplan, L. A. Miller, and J. A. Poupard Antimicrob. Agents Chemother. January 1999 43: 185-186; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Six New Fluoroquinolones against Brucella melitensis Ignacio Trujillano-Martín, Enrique García-Sánchez, Isaías Montes Martínez, María José Fresnadillo, José Elías García-Sánchez, and José Ángel García-Rodríguez Antimicrob. Agents Chemother. January 1999 43: 194-195; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Vancomycin-Dependent Enterococcus faecalis Clinical Isolates and Revertant Mutants Françoise Van Bambeke, Murielle Chauvel, Peter E. Reynolds, Henry S. Fraimow, and Patrice Courvalin Antimicrob. Agents Chemother. January 1999 43: 41-47; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Erythromycin Resistance Genes in Group A Streptococci in Finland Janne Kataja, Pentti Huovinen, Mikael Skurnik, the Finnish Study Group for Antimicrobial Resistance, and Helena Seppälä Antimicrob. Agents Chemother. January 1999 43: 48-52; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Type II Topoisomerase Mutations in Ciprofloxacin-Resistant Strains of Pseudomonas aeruginosa Hyam Mouneimné, Jérome Robert, Vincent Jarlier, and Emmanuelle Cambau Antimicrob. Agents Chemother. January 1999 43: 62-66; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Dihydrofolate Reductase Genes from Trimethoprim-Susceptible and Trimethoprim-Resistant Strains of Enterococcus faecalis Teresa M. Coque, Kavindra V. Singh, George M. Weinstock, and Barbara E. Murray Antimicrob. Agents Chemother. January 1999 43: 141-147; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of a Streptomycin/Spectinomycin Adenylyltransferase Gene (aadA) in Enterococcus faecalis Nancye C. Clark, Ørjan Olsvik, Jana M. Swenson, Carol A. Spiegel, and Fred C. Tenover Antimicrob. Agents Chemother. January 1999 43: 157-160; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Increase in Quinolone Resistance in a Haemophilus influenzae Strain Isolated from a Patient with Recurrent Respiratory Infections Treated with Ofloxacin Jordi Vila, Joaquim Ruiz, Ferran Sanchez, Ferran Navarro, Beatriz Mirelis, M. Teresa Jimenez de Anta, and Guillem Prats Antimicrob. Agents Chemother. January 1999 43: 161-162; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ADP-Ribosylation as an Intermediate Step in Inactivation of Rifampin by a Mycobacterial Gene Selwyn Quan, Tamae Imai, Yuzuru Mikami, Katsukiyo Yazawa, Eric R. Dabbs, Naoko Morisaki, Shigeo Iwasaki, Yuichi Hashimoto, and Kazuo Furihata Antimicrob. Agents Chemother. January 1999 43: 181-184; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of an Efflux Pump Gene, pmrA, Associated with Fluoroquinolone Resistance in Streptococcus pneumoniae Martin J. Gill, Nigel P. Brenwald, and Richard Wise Antimicrob. Agents Chemother. January 1999 43: 187-189; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Evaluation of a Novel, Anti-Herpes Simplex Virus Compound, Acyclovir Elaidate (P-4010), in the Female Guinea Pig Model of Genital Herpes R. Jennings, T. L. Smith, F. Myhren, J. Phillips, and M. L. Sandvold Antimicrob. Agents Chemother. January 1999 43: 53-61; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Population Pharmacokinetics of Nevirapine, Zidovudine, and Didanosine in Human Immunodeficiency Virus-Infected Patients Xiao-Jian Zhou, Lewis B. Sheiner, Richard T. D'Aquila, Michael D. Hughes, Martin S. Hirsch, Margaret A. Fischl, Victoria A. Johnson, Maureen Myers, Jean-Pierre Sommadossi, and The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators Antimicrob. Agents Chemother. January 1999 43: 121-128; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Metabolic Studies on BMS-200475, a New Antiviral Compound Active against Hepatitis B Virus Gregory Yamanaka, Todd Wilson, Steven Innaimo, Gregory S. Bisacchi, Peter Egli, J. Kent Rinehart, Robert Zahler, and Richard J. Colonno Antimicrob. Agents Chemother. January 1999 43: 190-193; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Therapeutic Effect of Clarithromycin on a Transplanted Tumor in Rats Kazuhiko Sassa, Yutaka Mizushima, Takashi Fujishita, Rokuo Oosaki, and Masashi Kobayashi Antimicrob. Agents Chemother. January 1999 43: 67-72; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Trovafloxacin in Treatment of Experimental Staphylococcal or Streptococcal Endocarditis J. M. Entenza, J. Vouillamoz, M. P. Glauser, and P. Moreillon Antimicrob. Agents Chemother. January 1999 43: 77-84; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Moxifloxacin (BAY12-8039), a New 8-Methoxyquinolone, Is Active in a Mouse Model of Tuberculosis Eishi Miyazaki, Miki Miyazaki, Jong Min Chen, Richard E. Chaisson, and William R. Bishai Antimicrob. Agents Chemother. January 1999 43: 85-89; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of the Ketolide HMR 3647 (RU 6647) for Legionella spp., Its Pharmacokinetics in Guinea Pigs, and Use of the Drug To Treat Guinea Pigs with Legionella pneumophila Pneumonia Paul H. Edelstein and Martha A. C. Edelstein Antimicrob. Agents Chemother. January 1999 43: 90-95; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity and Diffusion of LY333328 in Experimental Endocarditis Due to Vancomycin-Resistant Enterococcus faecalis Azzam Saleh-Mghir, Agnès Lefort, Yolande Petegnief, Sophie Dautrey, Jean-Marie Vallois, Dominique Le Guludec, Claude Carbon, and Bruno Fantin Antimicrob. Agents Chemother. January 1999 43: 115-120; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Evaluation of Second-Line Oral Treatments of Visceral Leishmaniasis Caused by Leishmania infantum Jean-Pierre Gangneux, Michael Dullin, Annie Sulahian, Yves Jean-Francois Garin, and Francis Derouin Antimicrob. Agents Chemother. January 1999 43: 172-174; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Chemistry; Biosynthesis:

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Mixture-Based Heterocyclic Combinatorial Positional Scanning Libraries: Discovery of Bicyclic Guanidines Having Potent Antifungal Activities against Candida albicans and Cryptococcus neoformans Sylvie E. Blondelle, Ema Crooks, John M. Ostresh, and Richard A. Houghten Antimicrob. Agents Chemother. January 1999 43: 106-114; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Targeting the Shikimate Pathway in the Malaria Parasite Plasmodium falciparum Glenn A. McConkey Antimicrob. Agents Chemother. January 1999 43: 175-177; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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In Vitro Susceptibilities of Lactobacilli and Organisms Associated with Bacterial Vaginosis to Melaleuca alternifolia (Tea Tree) Oil K. A. Hammer, C. F. Carson, and T. V. Riley Antimicrob. Agents Chemother. January 1999 43: 196 [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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Population Pharmacokinetics of Ceftizoxime Administered by Continuous Infusion in Clinically Ill Adult Patients Bryan Facca, Bill Frame, and Steve Triesenberg Antimicrob. Agents Chemother. January 1999 43: 197 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.