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Minireviews:

Jean-Marie Ghuysen and Colette Goffin

Lack of Cell Wall Peptidoglycan versus Penicillin Sensitivity: New Insights into the Chlamydial Anomaly
Antimicrob. Agents Chemother. 1999 43: 2339-2344. [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Markus Müller, Heino Staß, Martin Brunner, Jan G. Möller, Edith Lackner, and Hans G. Eichler

Penetration of Moxifloxacin into Peripheral Compartments in Humans
Antimicrob. Agents Chemother. 1999 43: 2345-2349. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dominique Breilh, Bernard Allaouchiche, Hélène Jaumain, Paul Boulétreau, Dominique Chassard, Isabelle Malbec, Dominique Ducint, and Marie-Claude Saux

Pharmacokinetics of Isepamicin during Continuous Venovenous Hemodiafiltration
Antimicrob. Agents Chemother. 1999 43: 2409-2411. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sandra L. Preston, George L. Drusano, Paul Glue, Jacqueline Nash, S. K. Gupta, and P. McNamara

Pharmacokinetics and Absolute Bioavailability of Ribavirin in Healthy Volunteers as Determined by Stable-Isotope Methodology
Antimicrob. Agents Chemother. 1999 43: 2451-2456. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christine Miossec-Bartoli, Lydie Pilatre, Pascale Peyron, Elsa-Noah N'Diaye, Véronique Collart-Dutilleul, Isabelle Maridonneau-Parini, and Anita Diu-Hercend

The New Ketolide HMR3647 Accumulates in the Azurophil Granules of Human Polymorphonuclear Cells
Antimicrob. Agents Chemother. 1999 43: 2457-2462. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Johan W. Mouton, Marc L. van Ogtrop, David Andes, and William A. Craig

Use of Pharmacodynamic Indices To Predict Efficacy of Combination Therapy In Vivo
Antimicrob. Agents Chemother. 1999 43: 2473-2478. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

So H. Kim, Jong W. Kwon, Won B. Kim, and Myung G. Lee

Effects of Cilastatin on the Pharmacokinetics of a New Carbapenem, DA-1131, in Rats, Rabbits, and Dogs
Antimicrob. Agents Chemother. 1999 43: 2524-2527. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Lipman, S. C. Wallis, and C. Rickard

Low Plasma Cefepime Levels in Critically Ill Septic Patients: Pharmacokinetic Modeling Indicates Improved Troughs with Revised Dosing
Antimicrob. Agents Chemother. 1999 43: 2559-2561. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kishor M. Wasan, Frank W. Strobel, Steven C. Parrott, Melvyn Lynn, William J. Christ, Lynn D. Hawkins, and Daniel P. Rossignol

Lipoprotein Distribution of a Novel Endotoxin Antagonist, E5531, in Plasma from Human Subjects with Various Lipid Levels
Antimicrob. Agents Chemother. 1999 43: 2562-2564. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Masanori Baba, Mika Okamoto, and Hitoshi Takeuchi

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Acutely and Chronically Infected Cells by EM2487, a Novel Substance Produced by a Streptomyces Species
Antimicrob. Agents Chemother. 1999 43: 2350-2355. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhengxian Gu, Mark A. Wainberg, Nghe Nguyen-Ba, Lucille L'Heureux, Jean-Marc de Muys, Terry L. Bowlin, and Robert F. Rando

Mechanism of Action and In Vitro Activity of 1',3'-Dioxolanylpurine Nucleoside Analogues against Sensitive and Drug-Resistant Human Immunodeficiency Virus Type 1 Variants
Antimicrob. Agents Chemother. 1999 43: 2376-2382. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Florence Morfin, Danielle Thouvenot, Mireille De Turenne-Tessier, Bruno Lina, Michèle Aymard, and Tadamasa Ooka

Phenotypic and Genetic Characterization of Thymidine Kinase from Clinical Strains of Varicella-Zoster Virus Resistant to Acyclovir
Antimicrob. Agents Chemother. 1999 43: 2412-2416. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. K. Patick, S. L. Binford, M. A. Brothers, R. L. Jackson, C. E. Ford, M. D. Diem, F. Maldonado, P. S. Dragovich, R. Zhou, T. J. Prins, S. A. Fuhrman, J. W. Meador, L. S. Zalman, D. A. Matthews, and S. T. Worland

In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease
Antimicrob. Agents Chemother. 1999 43: 2444-2450. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kazuhisa Yoshimura, Ron Feldman, Eiichi Kodama, Mark F. Kavlick, Yao-Ling Qiu, Jiri Zemlicka, and Hiroaki Mitsuya

In Vitro Induction of Human Immunodeficiency Virus Type 1 Variants Resistant to Phosphoralaninate Prodrugs of Z-Methylenecyclopropane Nucleoside Analogues
Antimicrob. Agents Chemother. 1999 43: 2479-2483. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark Thornton, Laura Barkley, Justin C. Mason, and Sunil Shaunak

Anti-Kaposi's Sarcoma and Antiangiogenic Activities of Sulfated Dextrins
Antimicrob. Agents Chemother. 1999 43: 2528-2533. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Anne M. J. A. Lenaerts, Sharon E. Chase, Alex J. Chmielewski, and Michael H. Cynamon

Evaluation of Rifapentine in Long-Term Treatment Regimens for Tuberculosis in Mice
Antimicrob. Agents Chemother. 1999 43: 2356-2360. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Erika J. Ernst, Satoru Hashimoto, Joseph Guglielmo, Teiji Sawa, Jean-Francois Pittet, Helmut Kropp, Jesse J. Jackson, and Jeanine P. Wiener-Kronish

Effects of Antibiotic Therapy on Pseudomonas aeruginosa-Induced Lung Injury in a Rat Model
Antimicrob. Agents Chemother. 1999 43: 2389-2394. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andreas H. Groll, Vidmantas Petraitis, Ruta Petraitiene, Aida Field-Ridley, Myrna Calendario, John Bacher, Stephen C. Piscitelli, and Thomas J. Walsh

Safety and Efficacy of Multilamellar Liposomal Nystatin against Disseminated Candidiasis in Persistently Neutropenic Rabbits
Antimicrob. Agents Chemother. 1999 43: 2463-2467. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lionel Piroth, Laurent Martin, Alexis Coulon, Catherine Lequeu, Michel Duong, Marielle Buisson, Henri Portier, and Pascal Chavanet

Development of a New Experimental Model of Penicillin-Resistant Streptococcus pneumoniae Pneumonia and Amoxicillin Treatment by Reproducing Human Pharmacokinetics
Antimicrob. Agents Chemother. 1999 43: 2484-2492. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mirjana Backo, Eliza Gaenger, Anna Burkart, Yin Li Chai, and Arnold S. Bayer

Treatment of Experimental Staphylococcal Endocarditis Due to a Strain with Reduced Susceptibility In Vitro to Vancomycin: Efficacy of Ampicillin-Sulbactam
Antimicrob. Agents Chemother. 1999 43: 2565-2568. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Thanugarani Padayachee and Keith P. Klugman

Molecular Basis of Rifampin Resistance in Streptococcus pneumoniae
Antimicrob. Agents Chemother. 1999 43: 2361-2365. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Lambert, Marie-Cécile Ploy, François Denis, and Patrice Courvalin

Characterization of the Chromosomal aac(6')-Iz Gene of Stenotrophomonas maltophilia
Antimicrob. Agents Chemother. 1999 43: 2366-2371. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Leon Iri Kupferwasser, Ronald A. Skurray, Melissa H. Brown, Neville Firth, Michael R. Yeaman, and Arnold S. Bayer

Plasmid-Mediated Resistance to Thrombin-Induced Platelet Microbicidal Protein in Staphylococci: Role of the qacA Locus
Antimicrob. Agents Chemother. 1999 43: 2395-2399. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michel Drancourt and Didier Raoult

Characterization of Mutations in the rpoB Gene in Naturally Rifampin-Resistant Rickettsia Species
Antimicrob. Agents Chemother. 1999 43: 2400-2403. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshikuni Onodera and Kenichi Sato

Molecular Cloning of the gyrA and gyrB Genes of Bacteroides fragilis Encoding DNA Gyrase
Antimicrob. Agents Chemother. 1999 43: 2423-2429. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Catherine Llanes, Veronique Kirchgesner, and Patrick Plesiat

Propagation of TEM- and PSE-Type -Lactamases among Amoxicillin-Resistant Salmonella spp. Isolated in France
Antimicrob. Agents Chemother. 1999 43: 2430-2436. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George E. Kenny, Patrick A. Young, Frank D. Cartwright, Karen E. Sjöström, and Wai M. Huang

Sparfloxacin Selects Gyrase Mutations in First-Step Mycoplasma hominis Mutants, whereas Ofloxacin Selects Topoisonmerase IV Mutations
Antimicrob. Agents Chemother. 1999 43: 2493-2496. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philipp Oster, Alessandra Zanchi, Stefania Cresti, Maria Lattanzi, Francesca Montagnani, Carla Cellesi, and Gian Maria Rossolini

Patterns of Macrolide Resistance Determinants among Community-Acquired Streptococcus pneumoniae Isolates over a 5-Year Period of Decreased Macrolide Susceptibility Rates
Antimicrob. Agents Chemother. 1999 43: 2510-2512. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sylvain Brisse, Ad C. Fluit, Ulrich Wagner, Peter Heisig, Dana Milatovic, Jan Verhoef, Sybille Scheuring, Karl Köhrer, and Franz-Josef Schmitz

Association of Alterations in ParC and GyrA Proteins with Resistance of Clinical Isolates of Enterococcus faecium to Nine Different Fluoroquinolones
Antimicrob. Agents Chemother. 1999 43: 2513-2516. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María José Ferrándiz, Jesús Oteo, Belén Aracil, Jose Luis Gómez-Garcés, and Adela G. De La Campa

Drug Efflux and parC Mutations Are Involved in Fluoroquinolone Resistance in Viridans Group Streptococci
Antimicrob. Agents Chemother. 1999 43: 2520-2523. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Heidi Segal, M. Victoria Francia, Juan M. García Lobo, and Gay Elisha

Reconstruction of an Active Integron Recombination Site after Integration of a Gene Cassette at a Secondary Site
Antimicrob. Agents Chemother. 1999 43: 2538-2541. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paolo Scarpellini, Sergio Braglia, Paola Carrera, Maura Cedri, Paola Cichero, Alessia Colombo, Rosella Crucianelli, Andrea Gori, Maurizio Ferrari, and Adriano Lazzarin

Detection of Rifampin Resistance in Mycobacterium tuberculosis by Double Gradient-Denaturing Gradient Gel Electrophoresis
Antimicrob. Agents Chemother. 1999 43: 2550-2554. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Frederic Fitoussi, Catherine Doit, Pierre Geslin, and Edouard Bingen

Killing Activities of Trovafloxacin Alone and in Combination with -Lactam Agents, Rifampin, or Vancomycin against Streptococcus pneumoniae Isolates with Various Susceptibilities to Extended-Spectrum Cephalosporins at Concentrations Clinically Achievable in Cerebrospinal Fluid
Antimicrob. Agents Chemother. 1999 43: 2372-2375. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jaana Mättö, Sirkka Asikainen, Marja-Liisa Väisänen, Birgitta Von Troil-Lindén, Eija Könönen, Maria Saarela, Kari Salminen, Sydney M. Finegold, and Hannele Jousimies-Somer

-Lactamase Production in Prevotella intermedia, Prevotella nigrescens, and Prevotella pallens Genotypes and In Vitro Susceptibilities to Selected Antimicrobial Agents
Antimicrob. Agents Chemother. 1999 43: 2383-2388. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Penelope N. Markham, Eric Westhaus, Katya Klyachko, Michael E. Johnson, and Alex A. Neyfakh

Multiple Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus
Antimicrob. Agents Chemother. 1999 43: 2404-2408. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. R. Snydman, N. V. Jacobus, L. A. McDermott, S. Supran, G. J. Cuchural, Jr., S. Finegold, L. Harrell, D. W. Hecht, P. Iannini, S. Jenkins, Carl Pierson, J. Rihs, and S. L. Gorbach

Multicenter Study of In Vitro Susceptibility of the Bacteroides fragilis Group, 1995 to 1996, with Comparison of Resistance Trends from 1990 to 1996
Antimicrob. Agents Chemother. 1999 43: 2417-2422. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rie Nagano, Yuka Adachi, Hideaki Imamura, Koji Yamada, Terutaka Hashizume, and Hajime Morishima

Carbapenem Derivatives as Potential Inhibitors of Various -Lactamases, Including Class B Metallo--Lactamases
Antimicrob. Agents Chemother. 1999 43: 2497-2503. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George G. Zhanel, James A. Karlowsky, Lorraine Palatnick, Laverne Vercaigne, Donald E. Low, The Canadian Respiratory Infection Study Group, and Daryl J. Hoban

Prevalence of Antimicrobial Resistance in Respiratory Tract Isolates of Streptococcus pneumoniae: Results of a Canadian National Surveillance Study
Antimicrob. Agents Chemother. 1999 43: 2504-2509. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annie-Claude Labbé, Anne-Marie Bourgault, Jean Vincelette, Pierre L. Turgeon, and François Lamothe

Trends in Antimicrobial Resistance among Clinical Isolates of the Bacteroides fragilis Group from 1992 to 1997 in Montreal, Canada
Antimicrob. Agents Chemother. 1999 43: 2517-2519. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. A. Schouten, A. Voss, J. A. A. Hoogkamp-Korstanje, and The European VRE Study Group

Antimicrobial Susceptibility Patterns of Enterococci Causing Infections in Europe
Antimicrob. Agents Chemother. 1999 43: 2542-2546. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Françoise Benoit-Vical, Anne Robert, and Bernard Meunier

Potentiation of Artemisinin Activity against Chloroquine-Resistant Plasmodium falciparum Strains by Using Heme Models
Antimicrob. Agents Chemother. 1999 43: 2555-2558. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrick Butaye, Luc A. Devriese, and Freddy Haesebrouck

Phenotypic Distinction in Enterococcus faecium and Enterococcus faecalis Strains between Susceptibility and Resistance to Growth-Enhancing Antibiotics
Antimicrob. Agents Chemother. 1999 43: 2569-2570. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ken B. Waites, Kay C. Canupp, and George E. Kenny

In Vitro Susceptibilities of Mycoplasma hominis to Six Fluoroquinolones as Determined by E Test
Antimicrob. Agents Chemother. 1999 43: 2571-2573. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Mahmoud H. el Kouni, Vincenzo Guarcello, Omar N. Al Safarjalani, and Fardos N. M. Naguib

Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii
Antimicrob. Agents Chemother. 1999 43: 2437-2443. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Leticia Zarantonelli, Graciela Borthagaray, Eun-Hee Lee, and William M. Shafer

Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Due to mtrR Mutations
Antimicrob. Agents Chemother. 1999 43: 2468-2472. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takashi Inui, Tadahiro Oshida, Toshio Endo, and Tadahiro Matsushita

Potent Bacteriolytic Activity of Ritipenem Associated with a Characteristic Profile of Affinities for Penicillin-Binding Proteins of Haemophilus influenzae
Antimicrob. Agents Chemother. 1999 43: 2534-2537. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susan L. Pendland, Mariela Diaz-Linares, Kevin W. Garey, Jennifer G. Woodward, Seonyoung Ryu, and Larry H. Danziger

Bactericidal Activity and Postantibiotic Effect of Levofloxacin against Anaerobes
Antimicrob. Agents Chemother. 1999 43: 2547-2549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. A. Pankuch, M. R. Jacobs, and P. C. Appelbaum

Postantibiotic Effects of Gatifloxacin against Gram-Positive and -Negative Organisms
Antimicrob. Agents Chemother. 1999 43: 2574-2575. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

R. Labia; and Yoshikazu Ishii

Analysis of the bla_toho Gene Coding for Toho-2--Lactamase
Antimicrob. Agents Chemother. 1999 43: 2576-2577. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.