Contents: February 1999, Volume 43, Issue 2        Minireviews        Susceptibility        Mechanisms of Action        Mechanisms of Resistance        Pharmacology        Antiviral Agents        Experimental Therapeutics        Letters        Errata Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Genetic Methods for Assessing Antimicrobial Resistance Franklin R. Cockerill, III Antimicrob. Agents Chemother. February 1999 43: 199-212; [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Comparative In Vitro Activities of Meropenem, Imipenem, Temocillin, Piperacillin, and Ceftazidime in Combination with Tobramycin, Rifampin, or Ciprofloxacin against Burkholderia cepacia Isolates from Patients with Cystic Fibrosis Stephane Bonacorsi, Frederic Fitoussi, Sylvie Lhopital, and Edouard Bingen Antimicrob. Agents Chemother. February 1999 43: 213-217; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Escherichia coli ATCC 35218 as a Quality Control Isolate for Susceptibility Testing of Haemophilus influenzae with Haemophilus Test Medium D. L. Butler, C. J. Jakielaszek, L. A. Miller, and J. A. Poupard Antimicrob. Agents Chemother. February 1999 43: 283-286; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Electrolytic Generation of Oxygen Partially Explains Electrical Enhancement of Tobramycin Efficacy against Pseudomonas aeruginosa Biofilm Philip S. Stewart, Wanida Wattanakaroon, Lu Goodrum, Susana M. Fortun, and Bruce R. McLeod Antimicrob. Agents Chemother. February 1999 43: 292-296; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of Newer Fluoroquinolones against Streptococcus pneumoniae Clinical Isolates Including Those with Mutations in the gyrA, parC, and parE Loci J. H. Jorgensen, L. M. Weigel, M. J. Ferraro, J. M. Swenson, and F. C. Tenover Antimicrob. Agents Chemother. February 1999 43: 329-334; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of NorA Inhibitors on In Vitro Antibacterial Activities and Postantibiotic Effects of Levofloxacin, Ciprofloxacin, and Norfloxacin in Genetically Related Strains of Staphylococcus aureus Jeffrey R. Aeschlimann, Linda D. Dresser, Glenn W. Kaatz, and Michael J. Rybak Antimicrob. Agents Chemother. February 1999 43: 335-340; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Resistance of 1,113 Streptococcus pneumoniae Isolates from Patients with Respiratory Tract Infections in Spain: Results of a 1-Year (1996-1997) Multicenter Surveillance Study Fernando Baquero, José Angel García-Rodríguez, Juan García de Lomas, Lorenzo Aguilar, and The Spanish Surveillance Group for Respiratory Pathogens Antimicrob. Agents Chemother. February 1999 43: 357-359; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enterococci with Acquired Vancomycin Resistance in Pigs and Chickens of Different Age Groups Patrick Butaye, Luc A. Devriese, Herman Goossens, Margaretha Ieven, and Freddy Haesebrouck Antimicrob. Agents Chemother. February 1999 43: 365-366; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Haemophilus influenzae and Moraxella catarrhalis from Patients with Community-Acquired Respiratory Tract Infections: Antimicrobial Susceptibility Patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997) Gary V. Doern, Ronald N. Jones, Michael A. Pfaller, Kari Kugler, and The Sentry Participants Group Antimicrob. Agents Chemother. February 1999 43: 385-389; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of a Heat-Induced Reformulation of Amphotericin B Deoxycholate (Fungizone) against Leishmania donovani C. Petit, V. Yardley, F. Gaboriau, J. Bolard, and S. L. Croft Antimicrob. Agents Chemother. February 1999 43: 390-392; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Benflumetol against 158 Senegalese Isolates of Plasmodium falciparum in Comparison with Those of Standard Antimalarial Drugs Bruno Pradines, Adama Tall, Thierry Fusai, Andre Spiegel, Remi Hienne, Christophe Rogier, Jean Francois Trape, Jacques Le Bras, and Daniel Parzy Antimicrob. Agents Chemother. February 1999 43: 418-420; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Activities of Clinafloxacin, Grepafloxacin, Levofloxacin, Moxifloxacin, Ofloxacin, Sparfloxacin, and Trovafloxacin and Nonquinolones Linozelid, Quinupristin-Dalfopristin, Gentamicin, and Vancomycin against Clinical Isolates of Ciprofloxacin-Resistant and -Susceptible Staphylococcus aureus Strains Mark E. Jones, Maarten R. Visser, Miriam Klootwijk, Peter Heisig, Jan Verhoef, and Franz-Josef Schmitz Antimicrob. Agents Chemother. February 1999 43: 421-423; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Italian Survey on Comparative Levofloxacin Susceptibility in 334 Clinical Isolates of Pseudomonas aeruginosa Bernardetta Segatore, Domenico Setacci, Mariagrazia Perilli, Nicola Franceschini, Annalisa De Santis, Federico Marchetti, and Gianfranco Amicosante Antimicrob. Agents Chemother. February 1999 43: 428-431; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Exposure to Antibiotics Induces Expression of the Mycobacterium tuberculosis sigF Gene: Implications for Chemotherapy against Mycobacterial Persistors Theresa M. Michele, Chiew Ko, and William R. Bishai Antimicrob. Agents Chemother. February 1999 43: 218-225; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amphotericin B and Fluconazole Affect Cellular Charge, Macrophage Phagocytosis, and Cellular Morphology of Cryptococcus neoformans at Subinhibitory Concentrations Joshua D. Nosanchuk, Wendy Cleare, Sarah P. Franzot, and Arturo Casadevall Antimicrob. Agents Chemother. February 1999 43: 233-239; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fungal Lethality, Binding, and Cytotoxicity of Syringomycin-E A. J. De Lucca, T. J. Jacks, J. Takemoto, B. Vinyard, J. Peter, E. Navarro, and T. J. Walsh Antimicrob. Agents Chemother. February 1999 43: 371-373; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mycobacteriocidal Action of Exogenous Nitric Oxide Richard Long, Bruce Light, and James A. Talbot Antimicrob. Agents Chemother. February 1999 43: 403-405; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Variation in the Composition and Pore Function of Major Outer Membrane Pore Protein P2 of Haemophilus influenzae from Cystic Fibrosis Patients Annette G. Regelink, David Dahan, Lieke V. M. Möller, James W. Coulton, Paul Eijk, Peter Van Ulsen, Jacob Dankert, and Loek Van Alphen Antimicrob. Agents Chemother. February 1999 43: 226-232; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

glmM Operon and Methicillin-Resistant glmM Suppressor Mutants in Staphylococcus aureus Philipp Glanzmann, John Gustafson, Hithoshi Komatsuzawa, Kouji Ohta, and Brigitte Berger-Bächi Antimicrob. Agents Chemother. February 1999 43: 240-245; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Stage-Specific Activity of Pentavalent Antimony against Leishmania donovani Axenic Amastigotes Moshe Ephros, Ari Bitnun, Pninit Shaked, Ella Waldman, and Dan Zilberstein Antimicrob. Agents Chemother. February 1999 43: 278-282; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Emergence of Multidrug-Resistant Mutants of Pseudomonas aeruginosa Overexpressing the Active Efflux System MexA-MexB-OprM Isabelle Ziha-Zarifi, Catherine Llanes, Thilo Köhler, Jean-Claude Pechere, and Patrick Plesiat Antimicrob. Agents Chemother. February 1999 43: 287-291; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization and Nucleotide Sequence of CARB-6, a New Carbenicillin-Hydrolyzing -Lactamase from Vibrio cholerae Danièle Choury, Gérald Aubert, Marie-France Szajnert, Kemal Azibi, Marc Delpech, and Gérard Paul Antimicrob. Agents Chemother. February 1999 43: 297-301; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ParC and GyrA May Be Interchangeable Initial Targets of Some Fluoroquinolones in Streptococcus pneumoniae Emmanuelle Varon, Claire Janoir, Marie-Dominique Kitzis, and Laurent Gutmann Antimicrob. Agents Chemother. February 1999 43: 302-306; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of SFO-1, a Plasmid-Mediated Inducible Class A -Lactamase from Enterobacter cloacae Yoshimi Matsumoto and Matsuhisa Inoue Antimicrob. Agents Chemother. February 1999 43: 307-313; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efflux Pump-Mediated Quinolone Resistance in Staphylococcus aureus Strains Wild Type for gyrA, gyrB, grlA, and norA Juan Luis Muñoz-Bellido, M. A. Alonso Manzanares, J. A. Martínez Andrés, M. N. Gutiérrez Zufiaurre, G. Ortiz, M. Segovia Hernández, and J. A. García-Rodríguez Antimicrob. Agents Chemother. February 1999 43: 354-356; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Updated Sequence Information for TEM -Lactamase Genes Sylvie Goussard and Patrice Courvalin Antimicrob. Agents Chemother. February 1999 43: 367-370; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutations in 23S rRNA in Helicobacter pylori Conferring Resistance to Erythromycin Do Not Always Confer Resistance to Clarithromycin M. Isabel García-Arata, Fernando Baquero, Luis de Rafael, Carlos Martín de Argila, Javier P. Gisbert, Fernando Bermejo, Daniel Boixeda, and Rafael Cantón Antimicrob. Agents Chemother. February 1999 43: 374-376; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Diversification of Escherichia coli Expressing an SHV-Type Extended-Spectrum -Lactamase (ESBL) during a Hospital Outbreak: Emergence of an ESBL-Hyperproducing Strain Resistant to Expanded-Spectrum Cephalosporins Andrzej Palucha, Barbara Mikiewicz, and Marek Gniadkowski Antimicrob. Agents Chemother. February 1999 43: 393-396; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance of Pseudomonas aeruginosa to Imipenem Induced by Eluates from Siliconized Latex Urinary Catheters Is Related to Outer Membrane Protein Alterations Luis Martínez-Martínez, Alvaro Pascual, María del Carmen Conejo, Leandro Picabea, and Evelio J. Perea Antimicrob. Agents Chemother. February 1999 43: 397-399; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interplay between Chromosomal -Lactamase and the MexAB-OprM Efflux System in Intrinsic Resistance to -Lactams in Pseudomonas aeruginosa Nobuhisa Masuda, Naomasa Gotoh, Chie Ishii, Eiko Sakagawa, Satoshi Ohya, and Takeshi Nishino Antimicrob. Agents Chemother. February 1999 43: 400-402; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of gyrA Mutations among 335 Pseudomonas aeruginosa Strains Isolated in Japan and Their Susceptibilities to Fluoroquinolones Takashi Takenouchi, Eiko Sakagawa, and Mie Sugawara Antimicrob. Agents Chemother. February 1999 43: 406-409; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Primary Targets of Fluoroquinolones in Streptococcus pneumoniae Hideyuki Fukuda and Keiichi Hiramatsu Antimicrob. Agents Chemother. February 1999 43: 410-412; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expression in Escherichia coli of a New Multidrug Efflux Pump, MexXY, from Pseudomonas aeruginosa Tomoyuki Mine, Yuji Morita, Atsuko Kataoka, Tohru Mizushima, and Tomofusa Tsuchiya Antimicrob. Agents Chemother. February 1999 43: 415-417; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Carbapenem Activities against Pseudomonas aeruginosa: Respective Contributions of OprD and Efflux Systems Thilo Köhler, Mehri Michea-Hamzehpour, Simone F. Epp, and Jean-Claude Pechere Antimicrob. Agents Chemother. February 1999 43: 424-427; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Mechanism Underlying Levofloxacin Uptake by Human Polymorphonuclear Neutrophils Doina Vazifeh, André Bryskier, and Marie-Thérèse Labro Antimicrob. Agents Chemother. February 1999 43: 246-252; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Mefloquine Combined with Artesunate in Children with Acute Falciparum Malaria Ric Price, Julie A. Simpson, Paktiya Teja-Isavatharm, Myint Myint Than, Christine Luxemburger, D. Gray Heppner, Tan Chongsuphajaisiddhi, François Nosten, and Nicholas J. White Antimicrob. Agents Chemother. February 1999 43: 341-346; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Genetic Variation and Susceptibilities to Protease Inhibitors among Subtype B and F Isolates in Brazil Amilcar Tanuri, Ana C. P. Vicente, Koko Otsuki, Carlos A. Ramos, Orlando C. Ferreira, Jr., Mauro Schechter, Luis M. Janini, Danuta Pieniazek, and Mark A. Rayfield Antimicrob. Agents Chemother. February 1999 43: 253-258; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Thiocarboxanilide Nonnucleoside Inhibitor UC781 Restores Antiviral Activity of 3'-Azido-3'-Deoxythymidine (AZT) against AZT-Resistant Human Immunodeficiency Virus Type 1 Gadi Borkow, Dominique Arion, Mark A. Wainberg, and Michael A. Parniak Antimicrob. Agents Chemother. February 1999 43: 259-263; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Rapid Non-Culture-Based Assay for Clinical Monitoring of Phenotypic Resistance of Human Immunodeficiency Virus Type 1 to Lamivudine (3TC) J. Gerardo García Lerma, Raymond F. Schinazi, Amy S. Juodawlkis, Vincent Soriano, Yulin Lin, Kathleen Tatti, David Rimland, Thomas M. Folks, and Walid Heneine Antimicrob. Agents Chemother. February 1999 43: 264-270; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Pharmacokinetics of 1-[((S)-2-Hydroxy-2-Oxo-1,4,2-Dioxaphosphorinan-5-yl)methyl]cytosine in Human Immunodeficiency Virus-Infected Patients Kenneth C. Cundy, Patricia Barditch-Crovo, Brent G. Petty, April Ruby, Murphy Redpath, Howard S. Jaffe, and Paul S. Lietman Antimicrob. Agents Chemother. February 1999 43: 271-277; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Broad-Spectrum Microbicide with Virucidal Activity against Sexually Transmitted Viruses M. K. Howett, E. B. Neely, N. D. Christensen, B. Wigdahl, F. C. Krebs, D. Malamud, S. D. Patrick, M. D. Pickel, P. A. Welsh, C. A. Reed, M. G. Ward, L. R. Budgeon, and J. W. Kreider Antimicrob. Agents Chemother. February 1999 43: 314-321; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antisense Oligonucleotide Inhibition of Hepatitis C Virus (HCV) Gene Expression in Livers of Mice Infected with an HCV-Vaccinia Virus Recombinant Hong Zhang, Ronnie Hanecak, Vickie Brown-Driver, Raana Azad, Boyd Conklin, Maureen C. Fox, and Kevin P. Anderson Antimicrob. Agents Chemother. February 1999 43: 347-353; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Herpesvirus 8 DNA Load in Leukocytes of Human Immunodeficiency Virus-Infected Subjects: Correlation with the Presence of Kaposi's Sarcoma and Response to Anticytomegalovirus Therapy Guy Boivin, Annie Gaudreau, Emil Toma, Richard Lalonde, Jean-Pierre Routy, Gilles Murray, Julie Handfield, and Michel G. Bergeron Antimicrob. Agents Chemother. February 1999 43: 377-380; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of the Antiviral Agent -D-2',3'-Didehydro-2',3'-Dideoxy-5-Fluorocytidine in Rhesus Monkeys Li Ma, Selwyn J. Hurwitz, Junxing Shi, Jeffrey J. McAtee, Dennis C. Liotta, Harold M. McClure, and Raymond F. Schinazi Antimicrob. Agents Chemother. February 1999 43: 381-384; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Comparison of a New Triazole Antifungal Agent, Schering 56592, with Itraconazole and Amphotericin B for Treatment of Histoplasmosis in Immunocompetent Mice Patricia Connolly, Joe Wheat, Carol Schnizlein-Bick, Michelle Durkin, Steve Kohler, Melinda Smedema, Janet Goldberg, Edward Brizendine, and David Loebenberg Antimicrob. Agents Chemother. February 1999 43: 322-328; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Therapeutic Effects of Benzoxazinorifamycin KRM-1648 Administered Alone or in Combination with a Half-Sized Secretory Leukocyte Protease Inhibitor or the Nonsteroidal Anti-Inflammatory Drug Diclofenac Sodium against Mycobacterium avium Complex Infection in Mice Chiaki Sano, Toshiaki Shimizu, Katsumasa Sato, Hideyuki Kawauchi, Shin Kawahara, and Haruaki Tomioka Antimicrob. Agents Chemother. February 1999 43: 360-364; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

An Alternative Animal Model for Comparison of Treatments for Cryptococcal Meningitis Laura K. Najvar, Rosie Bocanegra, and John R. Graybill Antimicrob. Agents Chemother. February 1999 43: 413-414; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Indinavir-Fluconazole Interaction S. Eralp Bellibas; and N. Clumeck Antimicrob. Agents Chemother. February 1999 43: 432-433; [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of a Ceftazidime-Resistant Morganella morganii Isolate Producing a TEM-10 -Lactamase H. Barroso, A. Freitas-Vieira, and A. Duarte Antimicrob. Agents Chemother. February 1999 43: 434-435; [Full Text] [PDF] [Reprints and Permissions]

Cefepime versus Ceftriaxone for Empiric Treatment of Hospitalized Patients with Community-Acquired Pneumonia Javier Borja, Francesc Jané;, and Marcus J. Zervos Antimicrob. Agents Chemother. February 1999 43: 436-437; [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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Rapid, Transient Fluconazole Resistance in Candida albicans Is Associated with Increased mRNA Levels of CDR Kieren A. Marr, Christopher N. Lyons, Tige R. Rustad, Raleigh A. Bowden, and Theodore C. White Antimicrob. Agents Chemother. February 1999 43: 438 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.