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Minireviews:

Marie-Paule Mingeot-Leclercq, Youri Glupczynski, and Paul M. Tulkens

Aminoglycosides: Activity and Resistance
Antimicrob. Agents Chemother. 1999 43: 727-737. [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

P. J. Petersen, N. V. Jacobus, W. J. Weiss, P. E. Sum, and R. T. Testa

In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9-t-Butylglycylamido Derivative of Minocycline (GAR-936)
Antimicrob. Agents Chemother. 1999 43: 738-744. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yigong Ge, Dorothy L. MacDonald, Kenneth J. Holroyd, Clyde Thornsberry, Hannah Wexler, and Michael Zasloff

In Vitro Antibacterial Properties of Pexiganan, an Analog of Magainin
Antimicrob. Agents Chemother. 1999 43: 782-788. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antonio Oliver, María Pérez-Vázquez, Manuel Martínez-Ferrer, Fernando Baquero, Luis de Rafael, and Rafael Cantón

Ampicillin-Sulbactam and Amoxicillin-Clavulanate Susceptibility Testing of Escherichia coli Isolates with Different -Lactam Resistance Phenotypes
Antimicrob. Agents Chemother. 1999 43: 862-867. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kumthorn Malathum, Teresa M. Coque, Kavindra V. Singh, and Barbara E. Murray

In Vitro Activities of Two Ketolides, HMR 3647 and HMR 3004, against Gram-Positive Bacteria
Antimicrob. Agents Chemother. 1999 43: 930-936. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel J. Diekema, Stacy L. Coffman, Steven A. Marshall, Mondell L. Beach, Kenneth V. I. Rolston, and Ronald N. Jones

Comparison of Activities of Broad-Spectrum -Lactam Compounds against 1,128 Gram-Positive Cocci Recently Isolated in Cancer Treatment Centers
Antimicrob. Agents Chemother. 1999 43: 940-943. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. L. Muñoz Bellido, M. A. Alonso Manzanares, G. Yagüe Guirao, M. N. Gutiérrez Zufiaurre, M. C. M. Toldos, M. Segovia Hernández, and J. A. García-Rodríguez

In Vitro Activities of 13 Fluoroquinolones against Staphylococcus aureus Isolates with Characterized Mutations in gyrA, gyrB, grlA, and norA and against Wild-Type Isolates
Antimicrob. Agents Chemother. 1999 43: 966-968. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. A. Sáez-Nieto and J. A. Vázquez

In Vitro Activities of Ketolides HRM 3647 and HRM 3004, Levofloxacin, and Other Quinolones and Macrolides against Neisseria spp. and Moraxella catarrhalis
Antimicrob. Agents Chemother. 1999 43: 983-984. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Betsy C. Herold, Risa Kirkpatrick, Daniel Marcellino, Anna Travelstead, Valentina Pilipenko, Holly Krasa, James Bremer, Li Jin Dong, and Morris D. Cooper

Bile Salts: Natural Detergents for the Prevention of Sexually Transmitted Diseases
Antimicrob. Agents Chemother. 1999 43: 745-751. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kenji Sudo, Wataru Watanabe, Kenji Konno, Ryu Sato, Tsuyoshi Kajiyashiki, Shiro Shigeta, and Tomoyuki Yokota

Efficacy of RD3-0028 Aerosol Treatment against Respiratory Syncytial Virus Infection in Immunosuppressed Mice
Antimicrob. Agents Chemother. 1999 43: 752-757. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Koen K. A. van Rompay, Julie M. Cherrington, Marta L. Marthas, Patrick D. Lamy, Peter J. Dailey, Don R. Canfield, Ross P. Tarara, Norbert Bischofberger, and Niels C. Pedersen

9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) Therapy Prolongs Survival of Infant Macaques Inoculated with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA
Antimicrob. Agents Chemother. 1999 43: 802-812. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Conti, A. de Marco, P. Mastromarino, P. Tomao, and M. G. Santoro

Antiviral Effect of Hyperthermic Treatment in Rhinovirus Infection
Antimicrob. Agents Chemother. 1999 43: 822-829. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Renata L. A. Bottrel, Yi-Li Yang, David E. Levy, Mark Tomai, and Luiz F. L. Reis

The Immune Response Modifier Imiquimod Requires STAT-1 for induction of Interferon, Interferon-Stimulated Genes, and Interleukin-6
Antimicrob. Agents Chemother. 1999 43: 856-861. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael S. Wyand, Kelledy H. Manson, Christopher J. Miller, and A. Robert Neurath

Effect of 3-Hydroxyphthaloyl--Lactoglobulin on Vaginal Transmission of Simian Immunodeficiency Virus in Rhesus Monkeys
Antimicrob. Agents Chemother. 1999 43: 978-980. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Anis A. Khan, Lewis H. Lambert, Jr., Jack S. Remington, and Fausto G. Araujo

Recombinant Bactericidal/Permeability-Increasing Protein (rBPI₂₁) in Combination with Sulfadiazine Is Active against Toxoplasma gondii
Antimicrob. Agents Chemother. 1999 43: 758-762. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tadashi Kohyama, Hajime Takizawa, Shin Kawasaki, Norihisa Akiyama, Makoto Sato, and Koji Ito

Fourteen-Member Macrolides Inhibit Interleukin-8 Release by Human Eosinophils from Atopic Donors
Antimicrob. Agents Chemother. 1999 43: 907-911. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ian Wiid, Eileen Hoal-van Helden, Dinie Hon, Carl Lombard, and Paul van Helden

Potentiation of Isoniazid Activity against Mycobacterium tuberculosis by Melatonin
Antimicrob. Agents Chemother. 1999 43: 975-977. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Kien C. Ha and Theodore C. White

Effects of Azole Antifungal Drugs on the Transition from Yeast Cells to Hyphae in Susceptible and Resistant Isolates of the Pathogenic Yeast Candida albicans
Antimicrob. Agents Chemother. 1999 43: 763-768. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Borann Sar, Kazunori Oishi, Akihiro Wada, Toshiya Hirayama, Kouji Matsushima, and Tsuyoshi Nagatake

Nitrite Reductase from Pseudomonas aeruginosa Released by Antimicrobial Agents and Complement Induces Interleukin-8 Production in Bronchial Epithelial Cells
Antimicrob. Agents Chemother. 1999 43: 794-801. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lisa J. Green, Philip Marder, Larry L. Mann, Li-Chun Chio, and William L. Current

LY303366 Exhibits Rapid and Potent Fungicidal Activity in Flow Cytometric Assays of Yeast Viability
Antimicrob. Agents Chemother. 1999 43: 830-835. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Kelly, Michael A. Miles, and Anita C. Skinner

The Anti-Influenza Virus Drug Rimantadine Has Trypanocidal Activity
Antimicrob. Agents Chemother. 1999 43: 985-987. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Laurent Poirel, Michele Guibert, Delphine Girlich, Thierry Naas, and Patrice Nordmann

Cloning, Sequence Analyses, Expression, and Distribution of ampC-ampR from Morganella morganii Clinical Isolates
Antimicrob. Agents Chemother. 1999 43: 769-776. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Toshinobu Horii, Taku Kimura, Kumiko Sato, Keigo Shibayama, and Michio Ohta

Emergence of Fosfomycin-Resistant Isolates of Shiga-Like Toxin-Producing Escherichia coli O26
Antimicrob. Agents Chemother. 1999 43: 789-793. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephanie A. Yoon, Jose A. Vazquez, Paul E. Steffan, Jack D. Sobel, and Robert A. Akins

High-Frequency, In Vitro Reversible Switching of Candida lusitaniae Clinical Isolates from Amphotericin B Susceptibility to Resistance
Antimicrob. Agents Chemother. 1999 43: 836-845. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Connie E. Briggs and Pina M. Fratamico

Molecular Characterization of an Antibiotic Resistance Gene Cluster of Salmonella typhimurium DT104
Antimicrob. Agents Chemother. 1999 43: 846-849. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bénédicte Fournier, Annie Gravel, David C. Hooper, and Paul H. Roy

Strength and Regulation of the Different Promoters for Chromosomal -Lactamases of Klebsiella oxytoca
Antimicrob. Agents Chemother. 1999 43: 850-855. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Simone Bagel, Volker Hüllen, Bernd Wiedemann, and Peter Heisig

Impact of gyrA and parC Mutations on Quinolone Resistance, Doubling Time, and Supercoiling Degree of Escherichia coli
Antimicrob. Agents Chemother. 1999 43: 868-875. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nezha Laraki, Moreno Galleni, Iris Thamm, Maria Letizia Riccio, Gianfranco Amicosante, Jean-Marie Frère, and Gian Maria Rossolini

Structure of In31, a bla_IMP-Containing Pseudomonas aeruginosa Integron Phyletically Related to In5, Which Carries an Unusual Array of Gene Cassettes
Antimicrob. Agents Chemother. 1999 43: 890-901. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nezha Laraki, Nicola Franceschini, Gian Maria Rossolini, Pasqualino Santucci, Cécile Meunier, Edwin de Pauw, Gianfranco Amicosante, Jean Marie Frère, and Moreno Galleni

Biochemical Characterization of the Pseudomonas aeruginosa 101/1477 Metallo--Lactamase IMP-1 Produced by Escherichia coli
Antimicrob. Agents Chemother. 1999 43: 902-906. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bülent Bozdogan, Latifa Berrezouga, Ming-Shang Kuo, David A. Yurek, Kathleen A. Farley, Brian J. Stockman, and Roland Leclercq

A New Resistance Gene, linB, Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025
Antimicrob. Agents Chemother. 1999 43: 925-929. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Santiago Hernández-Allés, Vicente J. Benedí, Luis Martínez-Martínez, Álvaro Pascual, Alicia Aguilar, Juan M. Tomás, and Sebastián Albertí

Development of Resistance during Antimicrobial Therapy Caused by Insertion Sequence Interruption of Porin Genes
Antimicrob. Agents Chemother. 1999 43: 937-939. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Arpin, H. Daube, F. Tessier, and C. Quentin

Presence of mefA and mefE Genes in Streptococcus agalactiae
Antimicrob. Agents Chemother. 1999 43: 944-946. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nagwa el Amin, Shah Jalal, and Bengt Wretlind

Alterations in GyrA and ParC Associated with Fluoroquinolone Resistance in Enterococcus faecium
Antimicrob. Agents Chemother. 1999 43: 947-949. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cécile M. Bebear, Joel Renaudin, Alain Charron, Hélène Renaudin, Bertille de Barbeyrac, Thierry Schaeverbeke, and Christiane Bebear

Mutations in the gyrA, parC, and parE Genes Associated with Fluoroquinolone Resistance in Clinical Isolates of Mycoplasma hominis
Antimicrob. Agents Chemother. 1999 43: 954-956. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. C. Nelson and B. Gay Elisha

Molecular Basis of AmpC Hyperproduction in Clinical Isolates of Escherichia coli
Antimicrob. Agents Chemother. 1999 43: 957-959. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chanwit Tribuddharat and Michael Fennewald

Integron-Mediated Rifampin Resistance in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 1999 43: 960-962. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Guillaume Arlet, Sylvie Goussard, Patrice Courvalin, and Alain Philippon

Sequences of the Genes for the TEM-20, TEM-21, TEM-22, and TEM-29 Extended-Spectrum -Lactamases
Antimicrob. Agents Chemother. 1999 43: 969-971. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. Bouza, F. Garcia-Garrote, E. Cercenado, M. Marin, and M. S. Diaz

Pseudomonas aeruginosa: a Survey of Resistance in 136 Hospitals in Spain
Antimicrob. Agents Chemother. 1999 43: 981-982. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Penelope N. Markham

Inhibition of the Emergence of Ciprofloxacin Resistance in Streptococcus pneumoniae by the Multidrug Efflux Inhibitor Reserpine
Antimicrob. Agents Chemother. 1999 43: 988-989. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John E. Gustafson, Pierre V. Candelaria, Scott A. Fisher, Jodie P. Goodridge, Tanya M. Lichocik, Tracy M. McWilliams, Christopher T. D. Price, Frances G. O'Brien, and Warren B. Grubb

Growth in the Presence of Salicylate Increases Fluoroquinolone Resistance in Staphylococcus aureus
Antimicrob. Agents Chemother. 1999 43: 990-992. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Peter J. Jenks, Agnes Labigne, and Richard L. Ferrero

Exposure to Metronidazole In Vivo Readily Induces Resistance in Helicobacter pylori and Reduces the Efficacy of Eradication Therapy in Mice
Antimicrob. Agents Chemother. 1999 43: 777-781. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. B. Breitschwerdt, M. G. Papich, B. C. Hegarty, B. Gilger, S. I. Hancock, and M. G. Davidson

Efficacy of Doxycycline, Azithromycin, or Trovafloxacin for Treatment of Experimental Rocky Mountain Spotted Fever in Dogs
Antimicrob. Agents Chemother. 1999 43: 813-821. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philip D. Lister, Victoria M. Gardner, and Christine C. Sanders

Clavulanate Induces Expression of the Pseudomonas aeruginosa AmpC Cephalosporinase at Physiologically Relevant Concentrations and Antagonizes the Antibacterial Activity of Ticarcillin
Antimicrob. Agents Chemother. 1999 43: 882-889. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sunil A. David, Richard Silverstein, Claudia R. Amura, Tammy Kielian, and David C. Morrison

Lipopolyamines: Novel Antiendotoxin Compounds That Reduce Mortality in Experimental Sepsis Caused by Gram-Negative Bacteria
Antimicrob. Agents Chemother. 1999 43: 912-919. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariana Gontijo Ramos, Eduardo Alves Bambirra, Jacques Robert Nicoli, Denise Carmona Cara, Enio Cardillo Vieira, and Jacqueline Alvarez-Leite

Protection by Short-Chain Fatty Acids against 1--D-Arabinofuranosylcytosine-Induced Intestinal Lesions in Germfree Mice
Antimicrob. Agents Chemother. 1999 43: 950-953. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dina Rodoni, Fränzi Hänni, Cynthia M. Gerber, Marianne Cottagnoud, Klaus Neftel, Martin G. Täuber, and Philippe Cottagnoud

Trovafloxacin in Combination with Vancomycin against Penicillin-Resistant Pneumococci in the Rabbit Meningitis Model
Antimicrob. Agents Chemother. 1999 43: 963-965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Amina Ahmed, Hasan Jafri, Irja Lutsar, Cynthia C. McCoig, Monica Trujillo, Loretta Wubbel, Sharon Shelton, and George H. McCracken, Jr.

Pharmacodynamics of Vancomycin for the Treatment of Experimental Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis
Antimicrob. Agents Chemother. 1999 43: 876-881. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lee T. Martin, Erika Cretton-Scott, Raymond F. Schinazi, Xiao-Jian Zhou, Harold M. McClure, Christophe Mathe, Gilles Gosselin, Jean-Louis Imbach, and Jean-Pierre Sommadossi

Pharmacokinetics of -L-2',3'-Dideoxy-5-Fluorocytidine in Rhesus Monkeys
Antimicrob. Agents Chemother. 1999 43: 920-924. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Diana P. Callender, Nalini Jayaprakash, Aaron Bell, Vidmantas Petraitis, Ruta Petratienes, Myrna Candelario, Robert Schaufele, James M. Dunn, Shizuko Sei, Thomas J. Walsh, and Frank M. Balis

Pharmacokinetics of Oral Zidovudine Entrapped in Biodegradable Nanospheres in Rabbits
Antimicrob. Agents Chemother. 1999 43: 972-974. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Recent Approvals:

New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 1998 and New Indications for Previously Approved Agents
Antimicrob. Agents Chemother. 1999 43: 993-994. [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Ana Lucia da Costa Darini, Marie-France I. Palepou, Dorothy James, and Neil Woodford

Disruption of vanS by IS1216V in a Clinical Isolate of Enterococcus faecium with VanA Glycopeptide Resistance
Antimicrob. Agents Chemother. 1999 43: 995-996. [Full Text] [PDF] [Reprints and Permissions]  

P. Diz, A. Ocampo, I. Iglesias, and I. Otero

Lack of Ritonavir Antifungal Effect In Vitro
Antimicrob. Agents Chemother. 1999 43: 997. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.