Contents: June 1999, Volume 43, Issue 6        Minireviews        Mechanisms of Action        Pharmacology        Mechanisms of Resistance        Susceptibility        Antiviral Agents        Experimental Therapeutics        Clinical Therapeutics        Letters        Author's Correction Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Peptide Antibiotics Robert E. W. Hancock and Daniel S. Chapple Antimicrob. Agents Chemother. June 1999 43: 1317-1323; [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Molecular Investigation of the Postantibiotic Effects of Clarithromycin and Erythromycin on Staphylococcus aureus Cells W. Scott Champney and Craig L. Tober Antimicrob. Agents Chemother. June 1999 43: 1324-1328; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Mechanism for the Synergistic Antimalarial Action of Atovaquone and Proguanil Indresh K. Srivastava and Akhil B. Vaidya Antimicrob. Agents Chemother. June 1999 43: 1334-1339; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Serine Protease Inhibitors Block Invasion of Host Cells by Toxoplasma gondii V. Conseil, M. Soête, and J. F. Dubremetz Antimicrob. Agents Chemother. June 1999 43: 1358-1361; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Intrapulmonary Concentrations of Pyrazinamide John E. Conte, Jr., Jeffrey A. Golden, Sheila Duncan, Elaine McKenna, and Elisabeth Zurlinden Antimicrob. Agents Chemother. June 1999 43: 1329-1333; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amphotericin B in Children with Malignant Disease: a Comparison of the Toxicities and Pharmacokinetics of Amphotericin B Administered in Dextrose versus Lipid Emulsion Christa E. Nath, Peter J. Shaw, Robyn Gunning, Andrew J. McLachlan, and John W. Earl Antimicrob. Agents Chemother. June 1999 43: 1417-1423; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Species Differences in the Proportion of Plasma Lipoprotein Lipid Carried by High-Density Lipoproteins Influence the Distribution of Free and Liposomal Nystatin in Human, Dog, and Rat Plasma Manisha Ramaswamy, Thomas L. Wallace, Paul A. Cossum, and Kishor M. Wasan Antimicrob. Agents Chemother. June 1999 43: 1424-1428; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Piperacillin and Tazobactam Exhibit Linear Pharmacokinetics after Multiple Standard Clinical Doses Barbara Auclair and Murray P. Ducharme Antimicrob. Agents Chemother. June 1999 43: 1465-1468; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of HSR-903, a New Fluoroquinolone, on the Concentration of Theophylline in Serum Yoshihito Niki, Shinsuke Watanabe, Sadao Tamada, Koichiro Yoshida, Naoyuki Miyashita, Masamitu Nakajima, Toshiharu Matsushima, Hisayuki Sekino, and Osamu Matsuoka Antimicrob. Agents Chemother. June 1999 43: 1494-1496; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics and Pharmacodynamics of Amoxicillin-Sulbactam, a Novel Aminopenicillin--Lactamase Inhibitor Combination, against Escherichia coli Carlos Bantar, Federico Nicola, Hector J. Arenoso, Marcelo Galas, Liliana Soria, Diego Dana, Alicia Rossi, Hebe Bianchini, and Abel Jasovich Antimicrob. Agents Chemother. June 1999 43: 1503-1504; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics and Inflammatory-Fluid Penetration of Moxifloxacin following Oral or Intravenous Administration Richard Wise, Jennifer M. Andrews, Gill Marshall, and Giles Hartman Antimicrob. Agents Chemother. June 1999 43: 1508-1510; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic-Pharmacodynamic Contributions to the Convulsant Activity of Fluoroquinolones in Rats Annie Delon, Serge Bouquet, Francois Huguet, Valerie Brunet, Philippe Courtois, and William Couet Antimicrob. Agents Chemother. June 1999 43: 1511-1515; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Azithromycin Administered Alone and with Atovaquone in Human Immunodeficiency Virus-Infected Children Leock Y. Ngo, Ram Yogev, Wayne M. Dankner, Walter T. Hughes, Sandra Burchett, Jing Xu, Brian Sadler, and Jashvant D. Unadkat Antimicrob. Agents Chemother. June 1999 43: 1516-1519; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in Pseudomonas aeruginosa Olga Lomovskaya, Angela Lee, Kazuki Hoshino, Hiroko Ishida, Anita Mistry, Mark S. Warren, Eric Boyer, Suzanne Chamberland, and Ving J. Lee Antimicrob. Agents Chemother. June 1999 43: 1340-1346; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization and Nucleotide Sequence of a Klebsiella oxytoca Cryptic Plasmid Encoding a CMY-Type -Lactamase: Confirmation that the Plasmid-Mediated Cephamycinase Originated from the Citrobacter freundii AmpC -Lactamase Shang Wei Wu, Kathrine Dornbusch, Göran Kronvall, and Mari Norgren Antimicrob. Agents Chemother. June 1999 43: 1350-1357; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

OXA-17, a Further Extended-Spectrum Variant of OXA-10 -Lactamase, Isolated from Pseudomonas aeruginosa Franck Danel, Lucinda M. C. Hall, Brigid Duke, Deniz Gur, and David M. Livermore Antimicrob. Agents Chemother. June 1999 43: 1362-1366; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Erythromycin-Resistant Neisseria gonorrhoeae and Oral Commensal Neisseria spp. Carry Known rRNA Methylase Genes Marilyn C. Roberts, Whasun O. Chung, Darcie Roe, Minsheng Xia, Carolina Marquez, G. Borthagaray, William L. Whittington, and King K. Holmes Antimicrob. Agents Chemother. June 1999 43: 1367-1372; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence of Antibiotic-Resistant Pseudomonas aeruginosa: Comparison of Risks Associated with Different Antipseudomonal Agents Yehuda Carmeli, Nicolas Troillet, George M. Eliopoulos, and Matthew H. Samore Antimicrob. Agents Chemother. June 1999 43: 1379-1382; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Nucleotide Sequence Determination of the Entire mec DNA of Pre-Methicillin-Resistant Staphylococcus aureus N315 T. Ito, Y. Katayama, and K. Hiramatsu Antimicrob. Agents Chemother. June 1999 43: 1449-1458; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Outer Membrane Permeability Barrier in Escherichia coli Mutants That Are Defective in the Late Acyltransferases of Lipid A Biosynthesis Martti Vaara and Marjatta Nurminen Antimicrob. Agents Chemother. June 1999 43: 1459-1462; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence in France of Multiple Clones of Clinical Streptococcus pneumoniae Isolates with High-Level Resistance to Amoxicillin Catherine Doit, Chawki Loukil, Frederic Fitoussi, Pierre Geslin, and Edouard Bingen Antimicrob. Agents Chemother. June 1999 43: 1480-1483; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rifampin and Rifabutin Resistance Mechanism in Helicobacter pylori Markus Heep, Daniela Beck, Ekkehard Bayerdörffer, and Norbert Lehn Antimicrob. Agents Chemother. June 1999 43: 1497-1499; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of Multidrug Resistance in Streptococcus mitis Susan M. Poutanen, Joyce de Azavedo, Barbara M. Willey, Donald E. Low, and Kelly S. MacDonald Antimicrob. Agents Chemother. June 1999 43: 1505-1507; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nomenclature for New Tetracycline Resistance Determinants Stuart B. Levy, Laura M. McMurry, Teresa M. Barbosa, Vickers Burdett, Patrice Courvalin, Wolfgang Hillen, Marilyn C. Roberts, Julian I. Rood, and Diane E. Taylor Antimicrob. Agents Chemother. June 1999 43: 1523-1524; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Antimicrobial Activities of Amine- and Guanidine-Functionalized Cholic Acid Derivatives Chunhong Li, Matthew R. Lewis, Amy B. Gilbert, Mark D. Noel, David H. Scoville, Glenn W. Allman, and Paul B. Savage Antimicrob. Agents Chemother. June 1999 43: 1347-1349; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Trailing End Point Phenotype in Antifungal Susceptibility Testing Is pH Dependent Kieren A. Marr, Tige R. Rustad, John H. Rex, and Theodore C. White Antimicrob. Agents Chemother. June 1999 43: 1383-1386; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of -Lactams and Macrolides against Helicobacter pylori Ibrahim J. Hassan, Roger M. Stark, John Greenman, and Michael R. Millar Antimicrob. Agents Chemother. June 1999 43: 1387-1392; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Use of Microdilution Panels with and without -Lactamase Inhibitors as a Phenotypic Test for -Lactamase Production among Escherichia coli, Klebsiella spp., Enterobacter spp., Citrobacter freundii, and Serratia marcescens Kenneth S. Thomson, Christine C. Sanders, and Ellen Smith Moland Antimicrob. Agents Chemother. June 1999 43: 1393-1400; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antifungal Activity of Nikkomycin Z in Combination with Fluconazole or Itraconazole R. K. Li and M. G. Rinaldi Antimicrob. Agents Chemother. June 1999 43: 1401-1405; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Designed Antimicrobial Peptides against Multidrug-Resistant Cystic Fibrosis Pathogens Ute Schwab, Peter Gilligan, Jesse Jaynes, and David Henke Antimicrob. Agents Chemother. June 1999 43: 1435-1440; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Susceptibilities of Candida and Cryptococcus neoformans Isolates from Blood Cultures of Neutropenic Patients Daryl J. Hoban, George G. Zhanel, and James A. Karlowsky Antimicrob. Agents Chemother. June 1999 43: 1463-1464; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Linezolid Activity Compared to Those of Selected Macrolides and Other Agents against Aerobic and Anaerobic Pathogens Isolated from Soft Tissue Bite Infections in Humans Ellie J. C. Goldstein, Diane M. Citron, and C. Vreni Merriam Antimicrob. Agents Chemother. June 1999 43: 1469-1474; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Gatifloxacin Compared to Those of Five Other Quinolones versus Aerobic and Anaerobic Isolates from Skin and Soft Tissue Samples of Human and Animal Bite Wound Infections Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Kerin TyRrell, and Yumi Warren Antimicrob. Agents Chemother. June 1999 43: 1475-1479; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Subpopulations of Helicobacter pylori Are Responsible for Discrepancies in the Outcome of Nitroimidazole Susceptibility Testing E. J. van der Wouden, A. de Jong, J. C. Thijs, J. H. Kleibeuker, and A. A. van Zwet Antimicrob. Agents Chemother. June 1999 43: 1484-1486; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antifungal Susceptibilities of Scopulariopsis Isolates C. Aguilar, I. Pujol, and J. Guarro Antimicrob. Agents Chemother. June 1999 43: 1520-1522; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Pyronaridine, Alone and in Combination with Other Antimalarial Drugs, against Plasmodium falciparum Pascal Ringwald, Else Carole Moukoko Eboumbou, Jean Bickii, and Leonardo K. Basco Antimicrob. Agents Chemother. June 1999 43: 1525-1527; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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ACTG 260: a Randomized, Phase I-II, Dose-Ranging Trial of the Anti-Human Immunodeficiency Virus Activity of Delavirdine Monotherapy Michael F. Para, Patricia Meehan, Jeanne Holden-Wiltse, Margaret Fischl, Gene Morse, Robert Shafer, Lisa M. Demeter, Kenneth Wood, Tom Nevin, Nzeera Virani-Ketter, and William W. Freimuth Antimicrob. Agents Chemother. June 1999 43: 1373-1378; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Anti-Human Immunodeficiency Virus Activities of Z- and E-Methylenecyclopropane Nucleoside Analogues and Their Phosphoro-L-Alaninate Diesters Hiroyuki Uchida, Eiichi N. Kodama, Kazuhisa Yoshimura, Yosuke Maeda, Pope Kosalaraksa, Victor Maroun, Yao-Ling Qiu, Jiri Zemlicka, and Hiroaki Mitsuya Antimicrob. Agents Chemother. June 1999 43: 1487-1490; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interstrain Variation in the Human Cytomegalovirus DNA Polymerase Sequence and Its Effect on Genotypic Diagnosis of Antiviral Drug Resistance Sunwen Chou, Nell S. Lurain, Adriana Weinberg, Guang-Yung Cai, Prem L. Sharma, Clyde S. Crumpacker, and Adult Aids Clinical Trials Group CMV Laboratories Antimicrob. Agents Chemother. June 1999 43: 1500-1502; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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In Vivo Efficacies of Combinations of -Lactams, -Lactamase Inhibitors, and Rifampin against Acinetobacter baumannii in a Mouse Pneumonia Model Michel Wolff, Marie-Laure Joly-Guillou, Robert Farinotti, and Claude Carbon Antimicrob. Agents Chemother. June 1999 43: 1406-1411; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Novel Antimicrobial Peptoids Bob Goodson, Anton Ehrhardt, Simon Ng, John Nuss, Kirk Johnson, Marty Giedlin, Ralph Yamamoto, Walter H. Moos, Anke Krebber, Martha Ladner, Mary Beth Giacona, Charles Vitt, and Jill Winter Antimicrob. Agents Chemother. June 1999 43: 1429-1434; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Azithromycin plus Rifampin versus That of Azithromycin Alone on the Eradication of Chlamydia pneumoniae from Lung Tissue in Experimental Pneumonitis Katerina Wolf and Raffaele Malinverni Antimicrob. Agents Chemother. June 1999 43: 1491-1493; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Randomized, Placebo-Controlled, Double-Blind Trial To Evaluate the Efficacy of Mupirocin for Eradicating Carriage of Methicillin-Resistant Staphylococcus aureus Stephan Harbarth, Sasi Dharan, Nadia Liassine, Pascale Herrault, Raymond Auckenthaler, and Didier Pittet Antimicrob. Agents Chemother. June 1999 43: 1412-1416; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Azithromycin versus Ciprofloxacin for Treatment of Uncomplicated Typhoid Fever in a Randomized Trial in Egypt That Included Patients with Multidrug Resistance Nabil I. Girgis, Thomas Butler, Robert W. Frenck, Yehia Sultan, Brown, David Tribble, and Rasik Khakhria Antimicrob. Agents Chemother. June 1999 43: 1441-1444; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of the Toxicity of Amphotericin B in 5% Dextrose with That of Amphotericin B in Fat Emulsion in a Randomized Trial with Cancer Patients Marcio Nucci, Monique Loureiro, Fernanda Silveira, Anna Raquel Casali, Luis Fernando Bouzas, Eduardo Velasco, Nelson Spector, and Wolmar Pulcheri Antimicrob. Agents Chemother. June 1999 43: 1445-1448; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Limitations of Cytomegalovirus Testing Johan Harmenberg, Maria Brytting;, Douglas A. Jabs, Michael S. Forman, and Cheryl L. Enger Antimicrob. Agents Chemother. June 1999 43: 1528-1529; [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Clarithromycin and Azithromycin against Clinical Isolates of Mycobacterium avium-M. intracellulare Lynn Steele-Moore, Kathleen Stark, and William J. Holloway Antimicrob. Agents Chemother. June 1999 43: 1530 [Full Text] [PDF] [Reprints and Permissions]

Increasing Resistance of Brucellae to Co-Trimoxazole A. Kinsara, A. Al-Mowallad, and A. O. Osoba Antimicrob. Agents Chemother. June 1999 43: 1531 [Full Text] [PDF] [Reprints and Permissions]

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Author's Correction:

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Eradication by Ceftriaxone of Streptococcus pneumoniae Isolates with Increased Resistance to Penicillin in Cases of Acute Otitis Media P. Gehanno, L. Nguyen, B. Barry, M. Derriennic, F. Pichon, J. M. Goehrs, and P. Berche Antimicrob. Agents Chemother. June 1999 43: 1532 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.