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Mechanisms of Resistance:

Samuel Bellais, Laurent Poirel, Thierry Naas, Delphine Girlich, and Patrice Nordmann

Genetic-Biochemical Analysis and Distribution of the Ambler Class A -Lactamase CME-2, Responsible for Extended-Spectrum Cephalosporin Resistance in Chryseobacterium (Flavobacterium) meningosepticum
Antimicrob. Agents Chemother. 2000 44: 1-9. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Margret Oethinger, Winfried V. Kern, Angelika S. Jellen-Ritter, Laura M. McMurry, and Stuart B. Levy

Ineffectiveness of Topoisomerase Mutations in Mediating Clinically Significant Fluoroquinolone Resistance in Escherichia coli in the Absence of the AcrAB Efflux Pump
Antimicrob. Agents Chemother. 2000 44: 10-13. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

I. I. Y. Ho, C. Y. Chan, and A. F. B. Cheng

Aminoglycoside Resistance in Mycobacterium kansasii, Mycobacterium avium-M. intracellulare, and Mycobacterium fortuitum: Are Aminoglycoside-Modifying Enzymes Responsible?
Antimicrob. Agents Chemother. 2000 44: 39-42. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David C. Lamb, Diane E. Kelly, Theodore C. White, and Steven L. Kelly

The R467K Amino Acid Substitution in Candida albicans Sterol 14-Demethylase Causes Drug Resistance through Reduced Affinity
Antimicrob. Agents Chemother. 2000 44: 63-67. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John Golin, Alisa Barkatt, Susan Cronin, George Eng, and Leopold May

Chemical Specificity of the PDR5 Multidrug Resistance Gene Product of Saccharomyces cerevisiae Based on Studies with Tri-n-Alkyltin Chlorides
Antimicrob. Agents Chemother. 2000 44: 134-138. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dieter Pfeifle, Eva Janas, and Bernd Wiedemann

Role of Penicillin-Binding Proteins in the Initiation of the AmpC -Lactamase Expression in Enterobacter cloacae
Antimicrob. Agents Chemother. 2000 44: 169-172. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Julien Haroche, Jeanine Allignet, Sylvie Aubert, Anthony E. Van Den Bogaard, and Névine El Solh

satG, Conferring Resistance to Streptogramin A, Is Widely Distributed in Enterococcus faecium Strains but Not in Staphylococci
Antimicrob. Agents Chemother. 2000 44: 190-191. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masatoshi Tanaka, Hiroshi Nakayama, Masashi Haraoka, Takeshi Saika, Intetsu Kobayashi, and Seiji Naito

Susceptibilities of Neisseria gonorrhoeae Isolates Containing Amino Acid Substitutions in GyrA, with or without Substitutions in ParC, to Newer Fluoroquinolones and Other Antibiotics
Antimicrob. Agents Chemother. 2000 44: 192-195. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helen M. Donald, Wendy Scaife, Sebastian G. B. Amyes, and Hilary-Kay Young

Sequence Analysis of ARI-1, a Novel OXA -Lactamase, Responsible for Imipenem Resistance in Acinetobacter baumannii 6B92
Antimicrob. Agents Chemother. 2000 44: 196-199. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anders Bäckman, Paula Orvelid, Julio A. Vazquez, Ola Sköld, and Per Olcén

Complete Sequence of a -Lactamase-Encoding Plasmid in Neisseria meningitidis
Antimicrob. Agents Chemother. 2000 44: 210-212. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helene Marchandin, Helene Jean-Pierre, Christophe De Champs, Danielle Sirot, Helene Darbas, Pierre Francois Perigault, and Christian Carriere

Production of a TEM-24 Plasmid-Mediated Extended-Spectrum -Lactamase by a Clinical Isolate of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 213-216. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Charlotte Verdet, Guillaume Arlet, Guilene Barnaud, Philippe H. Lagrange, and Alain Philippon

A Novel Integron in Salmonella enterica Serovar Enteritidis, Carrying the bla_DHA-1 Gene and Its Regulator Gene ampR, Originated from Morganella morganii
Antimicrob. Agents Chemother. 2000 44: 222-225. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Edna S. Kaneshiro, Donggeun Sul, and Banasri Hazra

Effects of Atovaquone and Diospyrin-Based Drugs on Ubiquinone Biosynthesis in Pneumocystis carinii Organisms
Antimicrob. Agents Chemother. 2000 44: 14-18. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thomas Akompong, Nafisa Ghori, and Kasturi Haldar

In Vitro Activity of Riboflavin against the Human Malaria Parasite Plasmodium falciparum
Antimicrob. Agents Chemother. 2000 44: 88-96. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Cristina Cruz, Maurizio Del Poeta, Ping Wang, Roland Wenger, Gerhard Zenke, Valerie F. J. Quesniaux, N. Rao Movva, John R. Perfect, Maria E. Cardenas, and Joseph Heitman

Immunosuppressive and Nonimmunosuppressive Cyclosporine Analogs Are Toxic to the Opportunistic Fungal Pathogen Cryptococcus neoformans via Cyclophilin-Dependent Inhibition of Calcineurin
Antimicrob. Agents Chemother. 2000 44: 143-149. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sheila K. Spangler, Saralee Bajaksouzian, Michael R. Jacobs, and Peter C. Appelbaum

Postantibiotic Effects of Grepafloxacin Compared to Those of Five Other Agents against 12 Gram-Positive and -Negative Bacteria
Antimicrob. Agents Chemother. 2000 44: 186-189. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Tetsuya Kuhara, Katsuhisa Uchida, and Hideyo Yamaguchi

Therapeutic Efficacy of Human Macrophage Colony-Stimulating Factor, Used Alone and in Combination with Antifungal Agents, in Mice with Systemic Candida albicans Infection
Antimicrob. Agents Chemother. 2000 44: 19-23. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Judith Molina, Olindo Martins-Filho, Zigman Brener, Alvaro J. Romanha, David Loebenberg, and Julio A. Urbina

Activities of the Triazole Derivative SCH 56592 (Posaconazole) against Drug-Resistant Strains of the Protozoan Parasite Trypanosoma (Schizotrypanum) cruzi in Immunocompetent and Immunosuppressed Murine Hosts
Antimicrob. Agents Chemother. 2000 44: 150-155. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hanne Hvidberg, Carsten Struve, Karen A. Krogfelt, Nils Christensen, Søren N. Rasmussen, and Niels Frimodt-Møller

Development of a Long-Term Ascending Urinary Tract Infection Mouse Model for Antibiotic Treatment Studies
Antimicrob. Agents Chemother. 2000 44: 156-163. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takashi Yokochi, Kayou Narita, Akiko Morikawa, Kazuko Takahashi, Yutaka Kato, Tuyoshi Sugiyama, Naoki Koide, Makoto Kawai, Masako Fukada, and Tomoaki Yoshida

Morphological Change in Pseudomonas aeruginosa following Antibiotic Treatment of Experimental Infection in Mice and Its Relation to Susceptibility to Phagocytosis and to Release of Endotoxin
Antimicrob. Agents Chemother. 2000 44: 205-206. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Marilaine Mota-Meira, Gisèle Lapointe, Christophe Lacroix, and Marc C. Lavoie

MICs of Mutacin B-Ny266, Nisin A, Vancomycin, and Oxacillin against Bacterial Pathogens
Antimicrob. Agents Chemother. 2000 44: 24-29. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shuichi Tawara, Fumiaki Ikeda, Katsuyuki Maki, Yoshihiko Morishita, Kazumi Otomo, Noriko Teratani, Toshio Goto, Masaki Tomishima, Hidenori Ohki, Akira Yamada, Koji Kawabata, Hisashi Takasugi, Kazuo Sakane, Hirokazu Tanaka, Fumio Matsumoto, and Shogo Kuwahara

In Vitro Activities of a New Lipopeptide Antifungal Agent, FK463, against a Variety of Clinically Important Fungi
Antimicrob. Agents Chemother. 2000 44: 57-62. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Herin Oh, Maria Hedberg, David Wade, and Charlotta Edlund

Activities of Synthetic Hybrid Peptides against Anaerobic Bacteria: Aspects of Methodology and Stability
Antimicrob. Agents Chemother. 2000 44: 68-72. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amy S. Piatek, Amalio Telenti, Megan R. Murray, Hiyam El-Hajj, William R. Jacobs, Jr., Fred Russell Kramer, and David Alland

Genotypic Analysis of Mycobacterium tuberculosis in Two Distinct Populations Using Molecular Beacons: Implications for Rapid Susceptibility Testing
Antimicrob. Agents Chemother. 2000 44: 103-110. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter G. Sohnle and Beth L. Hahn

Effect of Zinc-Reversible Growth-Inhibitory Activity in Human Empyema Fluid on Antibiotic Microbicidal Activity
Antimicrob. Agents Chemother. 2000 44: 139-142. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ricardo Fernández-Roblas, Jaime Esteban, Froilán Cabria, Juan Carlos López, Maria Soledad Jiménez, and Francisco Soriano

In Vitro Susceptibilities of Rapidly Growing Mycobacteria to Telithromycin (HMR 3647) and Seven Other Antimicrobials
Antimicrob. Agents Chemother. 2000 44: 181-182. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Francesco Barchiesi, Daniela Arzeni, Annette W. Fothergill, Luigi Falconi Di Francesco, Francesca Caselli, Michael G. Rinaldi, and Giorgio Scalise

In Vitro Activities of the New Antifungal Triazole SCH 56592 against Common and Emerging Yeast Pathogens
Antimicrob. Agents Chemother. 2000 44: 226-229. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Jocelyne Piret, André Désormeaux, Pierrette Gourde, Julianna Juhász, and Michel G. Bergeron

Efficacies of Topical Formulations of Foscarnet and Acyclovir and of 5-Percent Acyclovir Ointment (Zovirax) in a Murine Model of Cutaneous Herpes Simplex Virus Type 1 Infection
Antimicrob. Agents Chemother. 2000 44: 30-38. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Julià Blanco, Jordi Barretina, Geoffrey Henson, Gary Bridger, Erik De Clercq, Bonaventura Clotet, and José A. Esté

The CXCR4 Antagonist AMD3100 Efficiently Inhibits Cell-Surface-Expressed Human Immunodeficiency Virus Type 1 Envelope-Induced Apoptosis
Antimicrob. Agents Chemother. 2000 44: 51-56. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. M. Barnett, A. Cadman, D. Gor, M. Dempsey, M. Walters, A. Candlin, M. Tisdale, P. J. Morley, I. J. Owens, R. J. Fenton, A. P. Lewis, E. C. J. Claas, G. F. Rimmelzwaan, R. De Groot, and A. D. M. E. Osterhaus

Zanamivir Susceptibility Monitoring and Characterization of Influenza Virus Clinical Isolates Obtained during Phase II Clinical Efficacy Studies
Antimicrob. Agents Chemother. 2000 44: 78-87. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alana M. Thackray and Hugh J. Field

Persistence of Infectious Herpes Simplex Virus Type 2 in the Nervous System in Mice after Antiviral Chemotherapy
Antimicrob. Agents Chemother. 2000 44: 97-102. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Franck Le Guerhier, Christian Pichoud, Sylviane Guerret, Michèle Chevallier, Catherine Jamard, Olivier Hantz, Xiu-Yan Li, Shu-Hui Chen, Ivan King, Christian Trépo, Yung-Chi Cheng, and Fabien Zoulim

Characterization of the Antiviral Effect of 2',3'-Dideoxy-2', 3'-Didehydro--L-5-Fluorocytidine in the Duck Hepatitis B Virus Infection Model
Antimicrob. Agents Chemother. 2000 44: 111-122. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. M. Szczech, P. Furman, G. R. Painter, D. W. Barry, K. Borroto-Esoda, T. B. Grizzle, M. R. Blum, J.-P. Sommadossi, R. Endoh, T. Niwa, M. Yamamoto, and C. Moxham

Safety Assessment, In Vitro and In Vivo, and Pharmacokinetics of Emivirine, a Potent and Selective Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1
Antimicrob. Agents Chemother. 2000 44: 123-130. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stefano Aquaro, Orson Wedgwood, Christopher Yarnold, Dominique Cahard, Ranjith Pathinara, Christopher McGuigan, Raffaele Calio', Erik de Clercq, Jan Balzarini, and Carlo Federico Perno

Activities of Masked 2',3'-Dideoxynucleoside Monophosphate Derivatives against Human Immunodeficiency Virus in Resting Macrophages
Antimicrob. Agents Chemother. 2000 44: 173-177. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sunwen Chou and Camie L. Meichsner

A Nine-Codon Deletion Mutation in the Cytomegalovirus UL97 Phosphotransferase Gene Confers Resistance to Ganciclovir
Antimicrob. Agents Chemother. 2000 44: 183-185. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Francesca Pica, Anna Teresa Palamara, Antonio Rossi, Alessandra De Marco, Carla Amici, and M. Gabriella Santoro

¹²-Prostaglandin J₂ Is a Potent Inhibitor of Influenza A Virus Replication
Antimicrob. Agents Chemother. 2000 44: 200-204. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph A. Vaccaro, K. Mark Parnell, Stephanie A. Terezakis, and Karen S. Anderson

Mechanism of Inhibition of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase by d4TTP: an Equivalent Incorporation Efficiency Relative to the Natural Substrate dTTP
Antimicrob. Agents Chemother. 2000 44: 217-221. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Ron Dagan, Eugene Leibovitz, Dan M. Fliss, Alberto Leiberman, Michael R. Jacobs, William Craig, and Pablo Yagupsky

Bacteriologic Efficacies of Oral Azithromycin and Oral Cefaclor in Treatment of Acute Otitis Media in Infants and Young Children
Antimicrob. Agents Chemother. 2000 44: 43-50. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard N. Greenberg, Michael T. Newman, Saeed Shariaty, and Richard W. Pectol

Ciprofloxacin, Lomefloxacin, or Levofloxacin as Treatment for Chronic Osteomyelitis
Antimicrob. Agents Chemother. 2000 44: 164-166. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alain Bicart-Sée, Patrice Massip, Marie-Denise Linas, and Annick Datry

Successful Treatment with Nitazoxanide of Enterocytozoon bieneusi Microsporidiosis in a Patient with AIDS
Antimicrob. Agents Chemother. 2000 44: 167-168. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Maria Vittoria Moretti, Sergio Pauluzzi, and Marina Cesana

Penetration of Rufloxacin into the Cerebrospinal Fluid in Patients with Inflamed and Uninflamed Meninges
Antimicrob. Agents Chemother. 2000 44: 73-77. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. Inselmann, A. Volkmann, and H. T. Heidemann

Comparison of the Effects of Liposomal Amphotericin B and Conventional Amphotericin B on Propafenone Metabolism and Hepatic Cytochrome P-450 in Rats
Antimicrob. Agents Chemother. 2000 44: 131-133. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. A. Peleman, V. Van De Velde, P. R. Germonpré, C. Fleurinck, M. T. Rosseel, and R. A. Pauwels

Trovafloxacin Concentrations in Airway Fluids of Patients with Severe Community-Acquired Pneumonia
Antimicrob. Agents Chemother. 2000 44: 178-180. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hlif Steingrimsdottir, Astrid Gruber, Carina Palm, Gunnar Grimfors, Mats Kalin, and Staffan Eksborg

Bioavailability of Aciclovir after Oral Administration of Aciclovir and Its Prodrug Valaciclovir to Patients with Leukopenia after Chemotherapy
Antimicrob. Agents Chemother. 2000 44: 207-209. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.