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Minireviews:

Lakshmi P. Kotra, Jalal Haddad, and Shahriar Mobashery

Aminoglycosides: Perspectives on Mechanisms of Action and Resistance and Strategies to Counter Resistance
Antimicrob. Agents Chemother. 2000 44: 3249-3256. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Antonella Lupetti, Akke Paulusma-Annema, Mick M. Welling, Sonia Senesi, Jaap T. van Dissel, and Peter H. Nibbering

Candidacidal Activities of Human Lactoferrin Peptides Derived from the N Terminus
Antimicrob. Agents Chemother. 2000 44: 3257-3263. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mira Edgerton, Svetlana E. Koshlukova, Marcelo W. B. Araujo, Rashmi C. Patel, Jin Dong, and Jeremy A. Bruenn

Salivary Histatin 5 and Human Neutrophil Defensin 1 Kill Candida albicans via Shared Pathways
Antimicrob. Agents Chemother. 2000 44: 3310-3316. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lijuan Zhang, Pawandeep Dhillon, Hong Yan, Susan Farmer, and Robert E. W. Hancock

Interactions of Bacterial Cationic Peptide Antibiotics with Outer and Cytoplasmic Membranes of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 3317-3321. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shwan Rachid, Knut Ohlsen, Wolfgang Witte, Jörg Hacker, and Wilma Ziebuhr

Effect of Subinhibitory Antibiotic Concentrations on Polysaccharide Intercellular Adhesin Expression in Biofilm-Forming Staphylococcus epidermidis
Antimicrob. Agents Chemother. 2000 44: 3357-3363. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frank Møller Aarestrup and Lars Bogø Jensen

Presence of Variations in Ribosomal Protein L16 Corresponding to Susceptibility of Enterococci to Oligosaccharides (Avilamycin and Evernimicin)
Antimicrob. Agents Chemother. 2000 44: 3425-3427. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Helen Giamarellou, Harry P. Bassaris, George Petrikkos, Wilhelm Busch, Michel Voulgarelis, Anastasia Antoniadou, Elisabeth Grouzi, and Nikolaos Zoumbos

Monotherapy with Intravenous Followed by Oral High-Dose Ciprofloxacin versus Combination Therapy with Ceftazidime plus Amikacin as Initial Empiric Therapy for Granulocytopenic Patients with Fever
Antimicrob. Agents Chemother. 2000 44: 3264-3271. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. R. Donald, F. A. Sirgel, T. P. Kanyok, L. H. Danziger, A. Venter, F. J. Botha, D. P. Parkin, H. I. Seifart, B. W. Van de Wal, J. S. Maritz, and D. A. Mitchison

Early Bactericidal Activity of Paromomycin (Aminosidine) in Patients with Smear-Positive Pulmonary Tuberculosis
Antimicrob. Agents Chemother. 2000 44: 3285-3287. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dennis L. Stevens, Leon G. Smith, Jon B. Bruss, Maureen A. McConnell-Martin, Sue E. Duvall, Wesley Mark Todd, and Barry Hafkin

Randomized Comparison of Linezolid (PNU-100766) versus Oxacillin-Dicloxacillin for Treatment of Complicated Skin and Soft Tissue Infections
Antimicrob. Agents Chemother. 2000 44: 3408-3413. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Kyong-Sook Paek, Mu-Yong Kim, Chang-Seok Lee, and Hasik Youn

In Vitro and In Vivo Activities of LB 10827, a New Oral Cephalosporin, against Respiratory Pathogens
Antimicrob. Agents Chemother. 2000 44: 3272-3277. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tom Chiller, Kouros Farrokhshad, Elmer Brummer, and David A. Stevens

Influence of Human Sera on the In Vitro Activity of the Echinocandin Caspofungin (MK-0991) against Aspergillus fumigatus
Antimicrob. Agents Chemother. 2000 44: 3302-3305. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joan C. Fung-Tomc, Beatrice Minassian, Benjamin Kolek, Elizabeth Huczko, Lauren Aleksunes, Terry Stickle, Thomas Washo, Elizabeth Gradelski, Lourdes Valera, and Daniel P. Bonner

Antibacterial Spectrum of a Novel Des-Fluoro(6) Quinolone, BMS-284756
Antimicrob. Agents Chemother. 2000 44: 3351-3356. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kwen-Tay Luh, Po-Ren Hsueh, Lee-Jene Teng, Hui-Ju Pan, Yu-Chi Chen, Jang-Jih Lu, Jiunn-Jong Wu, and Shen-Wu Ho

Quinupristin-Dalfopristin Resistance among Gram-Positive Bacteria in Taiwan
Antimicrob. Agents Chemother. 2000 44: 3374-3380. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Maurin, N. F. Mersali, and D. Raoult

Bactericidal Activities of Antibiotics against Intracellular Francisella tularensis
Antimicrob. Agents Chemother. 2000 44: 3428-3431. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. R. Snydman, N. V. Jacobus, L. A. McDermott, J. R. Lonks, and J. M. Boyce

Comparative In Vitro Activities of Daptomycin and Vancomycin against Resistant Gram-Positive Pathogens
Antimicrob. Agents Chemother. 2000 44: 3447-3450. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Giacometti, Oscar Cirioni, Maria Simona Del Prete, Francesco Barchiesi, and Giorgio Scalise

Short-Term Exposure to Membrane-Active Antibiotics Inhibits Cryptosporidium parvum Infection in Cell Culture
Antimicrob. Agents Chemother. 2000 44: 3473-3475. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey L. Watts and Silvia Rossbach

Susceptibilities of Corynebacterium bovis and Corynebacterium amylocolatum Isolates from Bovine Mammary Glands to 15 Antimicrobial Agents
Antimicrob. Agents Chemother. 2000 44: 3476-3477. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Toshihiko Kira, Susan P. Grill, Ginger E. Dutschman, Ju-Sheng Lin, Fucheng Qu, Yongseok Choi, Chung K. Chu, and Yung-Chi Cheng

Anti-Epstein-Barr Virus (EBV) Activity of -L-5-Iododioxolane Uracil Is Dependent on EBV Thymidine Kinase
Antimicrob. Agents Chemother. 2000 44: 3278-3284. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lei Fu and Yung-Chi Cheng

Characterization of Novel Human Hepatoma Cell Lines with Stable Hepatitis B Virus Secretion for Evaluating New Compounds against Lamivudine- and Penciclovir-Resistant Virus
Antimicrob. Agents Chemother. 2000 44: 3402-3407. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. K. Powell, M. E. Gates, G. Langford, M.-L. Gu, C. Lockey, Z. Long, and E. Otto

Antiretroviral Agents Inhibit Infection of Human Cells by Porcine Endogenous Retroviruses
Antimicrob. Agents Chemother. 2000 44: 3432-3433. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marianne Savès, François Raffi, Philippe Clevenbergh, Bruno Marchou, Anne Waldner-Combernoux, Philippe Morlat, Vincent Le Moing, Catherine Rivière, Geneviève Chêne, Catherine Leport, and The APROCO Study Group

Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease Inhibitor-Containing Antiretroviral Regimen in Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 2000 44: 3451-3455. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter R. Meyer, Suzanne E. Matsuura, Raymond F. Schinazi, Antero G. So, and Walter A. Scott

Differential Removal of Thymidine Nucleotide Analogues from Blocked DNA Chains by Human Immunodeficiency Virus Reverse Transcriptase in the Presence of Physiological Concentrations of 2'-Deoxynucleoside Triphosphates
Antimicrob. Agents Chemother. 2000 44: 3465-3472. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Ute Dreses-Werringloer, Ingrid Padubrin, Barbara Jürgens-Saathoff, Alan P. Hudson, H. Zeidler, and L. Köhler

Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro
Antimicrob. Agents Chemother. 2000 44: 3288-3297. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Giacometti, Oscar Cirioni, Roberto Ghiselli, Luigi Goffi, Federico Mocchegiani, Alessandra Riva, Giorgio Scalise, and Vittorio Saba

Polycationic Peptides as Prophylactic Agents against Methicillin-Susceptible or Methicillin-Resistant Staphylococcus epidermidis Vascular Graft Infection
Antimicrob. Agents Chemother. 2000 44: 3306-3309. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. R. Rovaldi, A. Pievsky, N. A. Sole, P. M. Friden, D. M. Rothstein, and P. Spacciapoli

Photoactive Porphyrin Derivative with Broad-Spectrum Activity against Oral Pathogens In Vitro
Antimicrob. Agents Chemother. 2000 44: 3364-3367. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jenna Roberts, Kathleen Schock, Susan Marino, and Vincent T. Andriole

Efficacies of Two New Antifungal Agents, the Triazole Ravuconazole and the Echinocandin LY-303366, in an Experimental Model of Invasive Aspergillosis
Antimicrob. Agents Chemother. 2000 44: 3381-3388. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antonio Martinez, Pablo Aviles, Elena Jimenez, Jesus Caballero, and Domingo Gargallo-Viola

Activities of Sordarins in Experimental Models of Candidiasis, Aspergillosis, and Pneumocystosis
Antimicrob. Agents Chemother. 2000 44: 3389-3394. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kavindra V. Singh, Karen K. Zscheck, and Barbara E. Murray

Efficacy of Telithromycin (HMR 3647) against Enterococci in a Mouse Peritonitis Model
Antimicrob. Agents Chemother. 2000 44: 3434-3437. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robin Patel, Kerryl E. Piper, Mark S. Rouse, and James M. Steckelberg

Linezolid Therapy of Staphylococcus aureus Experimental Osteomyelitis
Antimicrob. Agents Chemother. 2000 44: 3438-3440. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Glenn P. Morlock, Bonnie B. Plikaytis, and Jack T. Crawford

Characterization of Spontaneous, In Vitro-Selected, Rifampin-Resistant Mutants of Mycobacterium tuberculosis Strain H37Rv
Antimicrob. Agents Chemother. 2000 44: 3298-3301. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nobuhisa Masuda, Eiko Sakagawa, Satoshi Ohya, Naomasa Gotoh, Hideto Tsujimoto, and Takeshi Nishino

Substrate Specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM Efflux Pumps in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 3322-3327. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Georg Sindelar, Xilin Zhao, Anthony Liew, Yuzhi Dong, Tao Lu, Jianfeng Zhou, John Domagala, and Karl Drlica

Mutant Prevention Concentration as a Measure of Fluoroquinolone Potency against Mycobacteria
Antimicrob. Agents Chemother. 2000 44: 3337-3343. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dilek Ince and David C. Hooper

Mechanisms and Frequency of Resistance to Premafloxacin in Staphylococcus aureus: Novel Mutations Suggest Novel Drug-Target Interactions
Antimicrob. Agents Chemother. 2000 44: 3344-3350. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cindy R. DeLoney and Neal L. Schiller

Characterization of an In Vitro-Selected Amoxicillin-Resistant Strain of Helicobacter pylori
Antimicrob. Agents Chemother. 2000 44: 3368-3373. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Tait-Kamradt, T. Davies, P. C. Appelbaum, F. Depardieu, P. Courvalin, J. Petitpas, L. Wondrack, A. Walker, M. R. Jacobs, and J. Sutcliffe

Two New Mechanisms of Macrolide Resistance in Clinical Strains of Streptococcus pneumoniae from Eastern Europe and North America
Antimicrob. Agents Chemother. 2000 44: 3395-3401. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annarita Mazzariol, Yutaka Tokue, Tiffany M. Kanegawa, Giuseppe Cornaglia, and Hiroshi Nikaido

High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA
Antimicrob. Agents Chemother. 2000 44: 3441-3443. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Libera M. Dalla Costa, Peter E. Reynolds, Helena A. P. H. M. Souza, Dilair C. Souza, Marie-France I. Palepou, and Neil Woodford

Characterization of a Divergent vanD-Type Resistance Element from the First Glycopeptide-Resistant Strain of Enterococcus faecium Isolated in Brazil
Antimicrob. Agents Chemother. 2000 44: 3444-3446. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susan Boyle-Vavra, Jongin Hahm, S. J. Sibener, and Robert S. Daum

Structural and Topological Differences between a Glycopeptide-Intermediate Clinical Strain and Glycopeptide-Susceptible Strains of Staphylococcus aureus Revealed by Atomic Force Microscopy
Antimicrob. Agents Chemother. 2000 44: 3456-3460. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rémy Durand, Jobin Eslahpazire, Sayeh Jafari, Jean-François Delabre, Anne Marmorat-Khuong, Jean-Philippe di Piazza, and Jacques Le Bras

Use of Molecular Beacons To Detect an Antifolate Resistance-Associated Mutation in Plasmodium falciparum
Antimicrob. Agents Chemother. 2000 44: 3461-3464. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

George S. Deepe, Jr. and Reta Gibbons

Recombinant Murine Granulocyte-Macrophage Colony-Stimulating Factor Modulates the Course of Pulmonary Histoplasmosis in Immunocompetent and Immunodeficient Mice
Antimicrob. Agents Chemother. 2000 44: 3328-3336. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Julie A. Simpson, Emmeline R. Watkins, Ric N. Price, Leon Aarons, Dennis E. Kyle, and Nicholas J. White

Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance
Antimicrob. Agents Chemother. 2000 44: 3414-3424. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hilte F. Geerdes-Fenge, Axel Wiedersich, S. Wagner, Karl-Heinz Lehr, Peter Koeppe, and Hartmut Lode

Levofloxacin Pharmacokinetics and Serum Bactericidal Activities against Five Enterobacterial Species
Antimicrob. Agents Chemother. 2000 44: 3478-3480. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

C. García-Rey, L. Aguilar, F. Baquero, and Spanish Surveillance Group for Respiratory Pathogens

Influences of Different Factors on Prevalence of Ciprofloxacin Resistance in Streptococcus pneumoniae in Spain
Antimicrob. Agents Chemother. 2000 44: 3481-3482. [Full Text] [PDF] [Reprints and Permissions]  

Tirushet Teshager, Lucas Domínguez, Miguel A. Moreno, Yolanda Saénz, Carmen Torres, and Susana Cardeñosa

Isolation of an SHV-12 -Lactamase-Producing Escherichia coli Strain from a Dog with Recurrent Urinary Tract Infections
Antimicrob. Agents Chemother. 2000 44: 3483-3484. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.