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Pharmacology:

Remco L. A. de Vrueh, Erik T. Rump, Erika van de Bilt, Richard van Veghel, Jan Balzarini, Erik A. L. Biessen, Theo J. C. van Berkel, and Martin K. Bijsterbosch

Carrier-Mediated Delivery of 9-(2-Phosphonylmethoxyethyl)Adenine to Parenchymal Liver Cells: a Novel Therapeutic Approach for Hepatitis B
Antimicrob. Agents Chemother. 2000 44: 477-483. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sophie Machard, Frederic Theodoro, Henri Benech, Jean-Marc Grognet, and Eric Ezan

A Sensitive Amphotericin B Immunoassay for Pharmacokinetic and Distribution Studies
Antimicrob. Agents Chemother. 2000 44: 546-550. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiroshi Uchino, Ikumi Tamai, Hikaru Yabuuchi, Kayoko China, Ken-ichi Miyamoto, Eiji Takeda, and Akira Tsuji

Faropenem Transport across the Renal Epithelial Luminal Membrane via Inorganic Phosphate Transporter Npt1
Antimicrob. Agents Chemother. 2000 44: 574-577. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Makoto Tanaka, Kinuyo Kato, Hideo Hakusui, Yoichi Murakami, Kenichi Sato, Yasushi Ito, and Keiji Kawamoto

Pharmacokinetics and Safety of Ascending Single Doses of DZ-2640, a New Oral Carbapenem Antibiotic, Administered to Healthy Japanese Subjects
Antimicrob. Agents Chemother. 2000 44: 578-582. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mohammed El Mouedden, Guy Laurent, Marie-Paule Mingeot-Leclercq, Henryk S. Taper, Jean Cumps, and Paul M. Tulkens

Apoptosis in Renal Proximal Tubules of Rats Treated with Low Doses of Aminoglycosides
Antimicrob. Agents Chemother. 2000 44: 665-675. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Ezzet, M. van Vugt, F. Nosten, S. Looareesuwan, and N. J. White

Pharmacokinetics and Pharmacodynamics of Lumefantrine (Benflumetol) in Acute Falciparum Malaria
Antimicrob. Agents Chemother. 2000 44: 697-704. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amin A. Nomeir, Pramila Kumari, Mary Jane Hilbert, Samir Gupta, David Loebenberg, Anthony Cacciapuoti, Roberta Hare, George H. Miller, Chin-Chung Lin, and Mitchell N. Cayen

Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys
Antimicrob. Agents Chemother. 2000 44: 727-731. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Christopher M. Parry, To Song Diep, John Wain, Nguyen Thi Tuyet Hoa, Mary Gainsborough, Diem Nga, Catrin Davies, Nguyen Hoan Phu, Tran Tinh Hien, Nicholas J. White, and Jeremy J. Farrar

Nasal Carriage in Vietnamese Children of Streptococcus pneumoniae Resistant to Multiple Antimicrobial Agents
Antimicrob. Agents Chemother. 2000 44: 484-488. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rie Nagano, Kaneyoshi Shibata, Yuka Adachi, Hideaki Imamura, Terutaka Hashizume, and Hajime Morishima

In Vitro Activities of Novel trans-3,5-Disubstituted Pyrrolidinylthio-1-Methylcarbapenems with Potent Activities against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 489-495. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Todd A. Davies, Linda M. Kelly, Dianne B. Hoellman, Lois M. Ednie, Catherine L. Clark, Saralee Bajaksouzian, Michael R. Jacobs, and Peter C. Appelbaum

Activities and Postantibiotic Effects of Gemifloxacin Compared to Those of 11 Other Agents against Haemophilus influenzae and Moraxella catarrhalis
Antimicrob. Agents Chemother. 2000 44: 633-639. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maurizio Del Poeta, M. Cristina Cruz, Maria E. Cardenas, John R. Perfect, and Joseph Heitman

Synergistic Antifungal Activities of Bafilomycin A₁, Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against Cryptococcus neoformans
Antimicrob. Agents Chemother. 2000 44: 739-746. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. A. Pfaller, R. N. Jones, G. V. Doern, H. S. Sader, S. A. Messer, A. Houston, S. Coffman, R. J. Hollis, and The SENTRY Participant Group

Bloodstream Infections Due to Candida Species: SENTRY Antimicrobial Surveillance Program in North America and Latin America, 1997-1998
Antimicrob. Agents Chemother. 2000 44: 747-751. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dwight Hardy, Daniel Amsterdam, Lionel A. Mandell, and Coleman Rotstein

Comparative In Vitro Activities of Ciprofloxacin, Gemifloxacin, Grepafloxacin, Moxifloxacin, Ofloxacin, Sparfloxacin, Trovafloxacin, and Other Antimicrobial Agents against Bloodstream Isolates of Gram-Positive Cocci
Antimicrob. Agents Chemother. 2000 44: 802-805. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Xin-Ru Pan-Zhou, Lixin Cui, Xiao-Jian Zhou, Jean-Pierre Sommadossi, and Victor M. Darley-Usmar

Differential Effects of Antiretroviral Nucleoside Analogs on Mitochondrial Function in HepG2 Cells
Antimicrob. Agents Chemother. 2000 44: 496-503. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Danni Colledge, Gilda Civitico, Stephen Locarnini, and Tim Shaw

In Vitro Antihepadnaviral Activities of Combinations of Penciclovir, Lamivudine, and Adefovir
Antimicrob. Agents Chemother. 2000 44: 551-560. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kurt Hertogs, Stuart Bloor, Veronique De Vroey, Christel van den Eynde, Pascale Dehertogh, Anja van Cauwenberge, Martin Stürmer, Timothy Alcorn, Scott Wegner, Margriet van Houtte, Veronica Miller, and Brendan A. Larder

A Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutational Pattern Confers Phenotypic Lamivudine Resistance in the Absence of Mutation 184V
Antimicrob. Agents Chemother. 2000 44: 568-573. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Etienne M. Sokal, Eve A. Roberts, Giorgina Mieli-Vergani, Penny McPhillips, Mark Johnson, Judy Barber, Nigel Dallow, Elizabeth Boxall, and Deirdre Kelly

A Dose Ranging Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of Lamivudine in Children and Adolescents with Chronic Hepatitis B
Antimicrob. Agents Chemother. 2000 44: 590-597. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marie L. Landry, Sylvia Stanat, Karen Biron, Donald Brambilla, William Britt, Janet Jokela, Sunwen Chou, W. Lawrence Drew, Alejo Erice, Bruce Gilliam, Nell Lurain, Jody Manischewitz, Richard Miner, Mostafa Nokta, Patricia Reichelderfer, Stephen Spector, Adriana Weinberg, Belinda Yen-Lieberman, Clyde Crumpacker, and the AIDS Clinical Trials Group CMV Resistance Working Group

A Standardized Plaque Reduction Assay for Determination of Drug Susceptibilities of Cytomegalovirus Clinical Isolates
Antimicrob. Agents Chemother. 2000 44: 688-692. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Giorgio Gatti, Alessandra Vigano', Natascia Sala, Stefano Vella, Matteo Bassetti, Dante Bassetti, and Nicola Principi

Indinavir Pharmacokinetics and Parmacodynamics in Children with Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 2000 44: 752-755. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis F. López-Cortés, R. Ruiz-Valderas, M. J. Lucero-Muñoz, E. Cordero, M. T. Pastor-Ramos, and J. Marquez

Intravitreal, Retinal, and Central Nervous System Foscarnet Concentrations after Rapid Intravenous Administration to Rabbits
Antimicrob. Agents Chemother. 2000 44: 756-759. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cheryl A. Stoddart, Mary E. Moreno, Valerie D. Linquist-Stepps, Christopher Bare, Mark R. Bogan, Alberto Gobbi, Robert W. Buckheit, Jr., Jean Bedard, Robert F. Rando, and Joseph M. McCune

Antiviral Activity of 2'-Deoxy-3'-Oxa-4'-Thiocytidine (BCH-10652) against Lamivudine-Resistant Human Immunodeficiency Virus Type 1 in SCID-hu Thy/Liv Mice
Antimicrob. Agents Chemother. 2000 44: 783-786. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. M. Demeter, R. W. Shafer, P. M. Meehan, J. Holden-Wiltse, M. A. Fischl, W. W. Freimuth, M. F. Para, and R. C. Reichman

Delavirdine Susceptibilities and Associated Reverse Transcriptase Mutations in Human Immunodeficiency Virus Type 1 Isolates from Patients in a Phase I/II Trial of Delavirdine Monotherapy (ACTG 260)
Antimicrob. Agents Chemother. 2000 44: 794-797. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Jeffrey R. Rose, Maureen A. Mullarkey, William J. Christ, Lynn D. Hawkins, Melvyn Lynn, Yoshito Kishi, Kishor M. Wasan, Kathy Peteherych, and Daniel P. Rossignol

Consequences of Interaction of a Lipophilic Endotoxin Antagonist with Plasma Lipoproteins
Antimicrob. Agents Chemother. 2000 44: 504-510. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Vazifeh, A. Bryskier, and M. T. Labro

Effect of Proinflammatory Cytokines on the Interplay between Roxithromycin, HMR 3647, or HMR 3004 and Human Polymorphonuclear Neutrophils
Antimicrob. Agents Chemother. 2000 44: 511-521. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Andrew Minnock, David I. Vernon, Jack Schofield, John Griffiths, J. Howard Parish, and Stanley B. Brown

Mechanism of Uptake of a Cationic Water-Soluble Pyridinium Zinc Phthalocyanine across the Outer Membrane of Escherichia coli
Antimicrob. Agents Chemother. 2000 44: 522-527. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Loraine Silvestro, Jeffrey N. Weiser, and Paul H. Axelsen

Antibacterial and Antimembrane Activities of Cecropin A in Escherichia coli
Antimicrob. Agents Chemother. 2000 44: 602-607. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wenyan Zhong, Matthew W. Jeffries, and Nafsika H. Georgopapadakou

Inhibition of Inositol Phosphorylceramide Synthase by Aureobasidin A in Candida and Aspergillus Species
Antimicrob. Agents Chemother. 2000 44: 651-653. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fiona C. Mortimer, David J. Mason, and Vanya A. Gant

Flow Cytometric Monitoring of Antibiotic-Induced Injury in Escherichia coli Using Cell-Impermeant Fluorescent Probes
Antimicrob. Agents Chemother. 2000 44: 676-681. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. J. Wickens, R. J. Pinney, D. J. Mason, and V. A. Gant

Flow Cytometric Investigation of Filamentation, Membrane Patency, and Membrane Potential in Escherichia coli following Ciprofloxacin Exposure
Antimicrob. Agents Chemother. 2000 44: 682-687. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melanie T. Cushion, Margaret Collins, Banasri Hazra, and Edna S. Kaneshiro

Effects of Atovaquone and Diospyrin-Based Drugs on the Cellular ATP of Pneumocystis carinii f. sp. carinii
Antimicrob. Agents Chemother. 2000 44: 713-719. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Agnes Rosenau, Blandine Cattier, Nathalie Gousset, Patrick Harriau, Alain Philippon, and Roland Quentin

Capnocytophaga ochracea: Characterization of a Plasmid-Encoded Extended-Spectrum TEM-17 -Lactamase in the Phylum Flavobacter-Bacteroides
Antimicrob. Agents Chemother. 2000 44: 760-762. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel Grenier, Marie-Pierre Huot, and Denis Mayrand

Iron-Chelating Activity of Tetracyclines and Its Impact on the Susceptibility of Actinobacillus actinomycetemcomitans to These Antibiotics
Antimicrob. Agents Chemother. 2000 44: 763-766. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rose Jung, Chad R. Messick, Susan L. Pendland, Eljim P. Tesoro, Karen J. Losendahl, Christopher A. Schriever, and Larry H. Danziger

Postantibiotic Effects and Bactericidal Activities of Clarithromycin-14-Hydroxy-Clarithromycin, versus Those of Amoxicillin-Clavulanate, against Anaerobes
Antimicrob. Agents Chemother. 2000 44: 778-779. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Shao-Ji Cheng, Louise Thibert, Tracy Sanchez, Leonid Heifets, and Ying Zhang

pncA Mutations as a Major Mechanism of Pyrazinamide Resistance in Mycobacterium tuberculosis: Spread of a Monoresistant Strain in Quebec, Canada
Antimicrob. Agents Chemother. 2000 44: 528-532. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Akio Kuga, Ryoichi Okamoto, and Matsuhisa Inoue

ampR Gene Mutations That Greatly Increase Class C -Lactamase Activity in Enterobacter cloacae
Antimicrob. Agents Chemother. 2000 44: 561-567. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Taimour Yousef Langaee, Luc Gagnon, and Ann Huletsky

Inactivation of the ampD Gene in Pseudomonas aeruginosa Leads to Moderate-Basal-Level and Hyperinducible AmpC -Lactamase Expression
Antimicrob. Agents Chemother. 2000 44: 583-589. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jacques Tankovic, Dominique Lamarque, Jean-Charles Delchier, Claude-James Soussy, Agnes Labigne, and Peter J. Jenks

Frequent Association between Alteration of the rdxA Gene and Metronidazole Resistance in French and North African Isolates of Helicobacter pylori
Antimicrob. Agents Chemother. 2000 44: 608-613. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Isabelle Le Thomas, Thierry Naas, Amal Karim, and Patrice Nordmann

Biochemical Sequence Analyses of GES-1, a Novel Class A Extended-Spectrum -Lactamase, and the Class 1 Integron In52 from Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2000 44: 622-632. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alexei Brooun, Songhua Liu, and Kim Lewis

A Dose-Response Study of Antibiotic Resistance in Pseudomonas aeruginosa Biofilms
Antimicrob. Agents Chemother. 2000 44: 640-646. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Seiji Kobayashi, Tomohisa Kuzuyama, and Haruo Seto

Characterization of the fomA and fomB Gene Products from Streptomyces wedmorensis, Which Confer Fosfomycin Resistance on Escherichia coli
Antimicrob. Agents Chemother. 2000 44: 647-650. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hideaki Maseda, Hiroshi Yoneyama, and Taiji Nakae

Assignment of the Substrate-Selective Subunits of the MexEF-OprN Multidrug Efflux Pump of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 658-664. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robin Patel, Kerryl Piper, Franklin R. Cockerill, III, James M. Steckelberg, and Allan A. Yousten

The Biopesticide Paenibacillus popilliae Has a Vancomycin Resistance Gene Cluster Homologous to the Enterococcal VanA Vancomycin Resistance Gene Cluster
Antimicrob. Agents Chemother. 2000 44: 705-709. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shah Jalal, Oana Ciofu, Niels Høiby, Naomasa Gotoh, and Bengt Wretlind

Molecular Mechanisms of Fluoroquinolone Resistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients
Antimicrob. Agents Chemother. 2000 44: 710-712. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter V. Adrian, Wenjun Zhao, Todd A. Black, Karen J. Shaw, Roberta S. Hare, and Keith P. Klugman

Mutations in Ribosomal Protein L16 Conferring Reduced Susceptibility to Evernimicin (SCH27899): Implications for Mechanism of Action
Antimicrob. Agents Chemother. 2000 44: 732-738. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karen P. Scott, Claire M. Melville, Teresa M. Barbosa, and Harry J. Flint

Occurrence of the New Tetracycline Resistance Gene tet(W) in Bacteria from the Human Gut
Antimicrob. Agents Chemother. 2000 44: 775-777. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. A. Franke, T. M. Bolman, S. A. Ottum, K. F. Jones, and D. E. Hruby

Streptococcus gordonii Strains Resistant to Fluorodeoxyuridine Contain Mutations in the Thymidine Kinase Gene and Are Deficient in Thymidine Kinase Activity
Antimicrob. Agents Chemother. 2000 44: 787-789. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Claire Poyart, Gilles Quesne, Philippe Acar, Patrick Berche, and Patrick Trieu-Cuot

Characterization of the Tn916-like Transposon Tn3872 in a Strain of Abiotrophia defectiva (Streptococcus defectivus) Causing Sequential Episodes of Endocarditis in a Child
Antimicrob. Agents Chemother. 2000 44: 790-793. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rebecca Beyer, Ekaterina Pestova, John J. Millichap, Valentina Stosor, Gary A. Noskin, and Lance R. Peterson

A Convenient Assay for Estimating the Possible Involvement of Efflux of Fluoroquinolones by Streptococcus pneumoniae and Staphylococcus aureus: Evidence for Diminished Moxifloxacin, Sparfloxacin, and Trovafloxacin Efflux
Antimicrob. Agents Chemother. 2000 44: 798-801. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Carol Cordeiro, David J. Wiseman, Peter Lutwyche, Mitchell Uh, Jennifer C. Evans, B. Brett Finlay, and Murray S. Webb

Antibacterial Efficacy of Gentamicin Encapsulated in pH-Sensitive Liposomes against an In Vivo Salmonella enterica Serovar Typhimurium Intracellular Infection Model
Antimicrob. Agents Chemother. 2000 44: 533-539. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Els W. M. Van Etten, Lorna E. T. Stearne-Cullen, Marian T. Ten Kate, and Irma A. J. M. Bakker-Woudenberg

Efficacy of Liposomal Amphotericin B with Prolonged Circulation in Blood in Treatment of Severe Pulmonary Aspergillosis in Leukopenic Rats
Antimicrob. Agents Chemother. 2000 44: 540-545. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie Hershberger and Michael J. Rybak

Activities of Trovafloxacin, Gatifloxacin, Clinafloxacin, Sparfloxacin, Levofloxacin, and Ciprofloxacin against Penicillin-Resistant Streptococcus pneumoniae in an In Vitro Infection Model
Antimicrob. Agents Chemother. 2000 44: 598-601. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fumiaki Ikeda, Yoshimi Wakai, Satoru Matsumoto, Katsuyuki Maki, Etsuko Watabe, Shuichi Tawara, Toshio Goto, Yuji Watanabe, Fumio Matsumoto, and Shogo Kuwahara

Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Disseminated Candidiasis and Aspergillosis
Antimicrob. Agents Chemother. 2000 44: 614-618. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Satoru Matsumoto, Yoshimi Wakai, Toru Nakai, Kazuo Hatano, Tomoe Ushitani, Fumiaki Ikeda, Shuichi Tawara, Toshio Goto, Fumio Matsumoto, and Shogo Kuwahara

Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2000 44: 619-621. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. I. Pelton, M. Figueira, R. Albut, and D. Stalker

Efficacy of Linezolid in Experimental Otitis Media
Antimicrob. Agents Chemother. 2000 44: 654-657. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Smirnov, A. Wellmer, J. Gerber, K. Maier, S. Henne, and R. Nau

Gemifloxacin Is Effective in Experimental Pneumococcal Meningitis
Antimicrob. Agents Chemother. 2000 44: 767-770. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea M. Rediske, Beverly L. Roeder, Jared L. Nelson, Rachel L. Robison, G. Bruce Schaalje, Richard A. Robison, and William G. Pitt

Pulsed Ultrasound Enhances the Killing of Escherichia coli Biofilms by Aminoglycoside Antibiotics In Vivo
Antimicrob. Agents Chemother. 2000 44: 771-772. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen H. Zinner, Kelly Simmons, and Deborah Gilbert

Comparative Activities of Ciprofloxacin and Levofloxacin against Streptococcus pneumoniae in an In Vitro Dynamic Model
Antimicrob. Agents Chemother. 2000 44: 773-774. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William R. Kirkpatrick, Robert K. McAtee, Annette W. Fothergill, David Loebenberg, Michael G. Rinaldi, and Thomas F. Patterson

Efficacy of SCH56592 in a Rabbit Model of Invasive Aspergillosis
Antimicrob. Agents Chemother. 2000 44: 780-782. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Yupin Suputtamongkol, Sunanta Intaranongpai, Michael D. Smith, Brian Angus, Wipada Chaowagul, Chairat Permpikul, Julie A. Simpson, Amorn Leelarasamee, Lloyd Curtis, and Nicholas J. White

A Double-Blind Placebo-Controlled Study of an Infusion of Lexipafant (Platelet-Activating Factor Receptor Antagonist) in Patients with Severe Sepsis
Antimicrob. Agents Chemother. 2000 44: 693-696. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Susan E. Jensen, Kenneth J. Elder, Kwamena A. Aidoo, and Ashish S. Paradkar

Enzymes Catalyzing the Early Steps of Clavulanic Acid Biosynthesis Are Encoded by Two Sets of Paralogous Genes in Streptomyces clavuligerus
Antimicrob. Agents Chemother. 2000 44: 720-726. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

L. V. Stamm and H. L. Bergen

A Point Mutation Associated with Bacterial Macrolide Resistance Is Present in Both 23S rRNA Genes of an Erythromycin-Resistant Treponema pallidum Clinical Isolate
Antimicrob. Agents Chemother. 2000 44: 806-807. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.