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Minireviews:

J. L. Martinez and F. Baquero

Mutation Frequencies and Antibiotic Resistance
Antimicrob. Agents Chemother. 2000 44: 1771-1777. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Ana Alonso, Patricia Sanchez, and José L. Martínez

Stenotrophomonas maltophilia D457R Contains a Cluster of Genes from Gram-Positive Bacteria Involved in Antibiotic and Heavy Metal Resistance
Antimicrob. Agents Chemother. 2000 44: 1778-1782. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeff N. Anderl, Michael J. Franklin, and Philip S. Stewart

Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin
Antimicrob. Agents Chemother. 2000 44: 1818-1824. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter S. Margolis, Corinne J. Hackbarth, Dennis C. Young, Wen Wang, Dawn Chen, Zhengyu Yuan, Richard White, and Joaquim Trias

Peptide Deformylase in Staphylococcus aureus: Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene
Antimicrob. Agents Chemother. 2000 44: 1825-1831. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rafik Bachoual, Luc Dubreuil, Claude-James Soussy, and Jacques Tankovic

Roles of gyrA Mutations in Resistance of Clinical Isolates and In Vitro Mutants of Bacteroides fragilis to the New Fluoroquinolone Trovafloxacin
Antimicrob. Agents Chemother. 2000 44: 1842-1845. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jungmin Kim and Hoan-Jong Lee

Rapid Discriminatory Detection of Genes Coding for SHV -Lactamases by Ligase Chain Reaction
Antimicrob. Agents Chemother. 2000 44: 1860-1864. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hans-Jörg Linde, Frank Notka, Michaela Metz, Bernd Kochanowski, Peter Heisig, and Norbert Lehn

In Vivo Increase in Resistance to Ciprofloxacin in Escherichia coli Associated with Deletion of the C-Terminal Part of MarR
Antimicrob. Agents Chemother. 2000 44: 1865-1868. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samuel Bellais, Daniel Aubert, Thierry Naas, and Patrice Nordmann

Molecular and Biochemical Heterogeneity of Class B Carbapenem-Hydrolyzing -Lactamases in Chryseobacterium meningosepticum
Antimicrob. Agents Chemother. 2000 44: 1878-1886. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Duarte C. Oliveira, Shang W. Wu, and Hermínia de Lencastre

Genetic Organization of the Downstream Region of the mecA Element in Methicillin-Resistant Staphylococcus aureus Isolates Carrying Different Polymorphisms of This Region
Antimicrob. Agents Chemother. 2000 44: 1906-1910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mohamed Younsi, Elise Ramanandraibe, Roger Bonaly, Mireille Donner, and Joël Coulon

Amphotericin B Resistance and Membrane Fluidity in Kluyveromyces lactis Strains
Antimicrob. Agents Chemother. 2000 44: 1911-1916. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Chanal, R. Bonnet, C. De Champs, D. Sirot, R. Labia, and J. Sirot

Prevalence of -Lactamases among 1,072 Clinical Strains of Proteus mirabilis: a 2-Year Survey in a French Hospital
Antimicrob. Agents Chemother. 2000 44: 1930-1935. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Bonnet, J. L. M. Sampaio, R. Labia, C. De Champs, D. Sirot, C. Chanal, and J. Sirot

A Novel CTX-M -Lactamase (CTX-M-8) in Cefotaxime-Resistant Enterobacteriaceae Isolated in Brazil
Antimicrob. Agents Chemother. 2000 44: 1936-1942. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert B. Giannattasio and Bernard Weisblum

Modulation of Erm Methyltransferase Activity by Peptides Derived from Phage Display
Antimicrob. Agents Chemother. 2000 44: 1961-1963. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Montserrat Sabaté, Raül Tarragó, Ferran Navarro, Elisenda Miró, Clara Vergés, Jordi Barbé, and Guillermo Prats

Cloning and Sequence of the Gene Encoding a Novel Cefotaxime-Hydrolyzing -Lactamase (CTX-M-9) from Escherichia coli in Spain
Antimicrob. Agents Chemother. 2000 44: 1970-1973. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Holly Z. Bazmi, Jennifer L. Hammond, Socrates C. H. Cavalcanti, Chung K. Chu, Raymond F. Schinazi, and John W. Mellors

In Vitro Selection of Mutations in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase That Decrease Susceptibility to ()--D-Dioxolane-Guanosine and Suppress Resistance to 3'-Azido-3'-Deoxythymidine
Antimicrob. Agents Chemother. 2000 44: 1783-1788. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

I. Arany, S. K. Tyring, M. M. Brysk, M. A. Stanley, M. A. Tomai, R. L. Miller, M. H. Smith, D. J. McDermott, and H. B. Slade

Correlation between Pretreatment Levels of Interferon Response Genes and Clinical Responses to an Immune Response Modifier (Imiquimod) in Genital Warts
Antimicrob. Agents Chemother. 2000 44: 1869-1873. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sabine Francke, Charles G. Orosz, Kathleen A. Hayes, and Lawrence E. Mathes

Effect of Zidovudine on the Primary Cytolytic T-Lymphocyte Response and T-Cell Effector Function
Antimicrob. Agents Chemother. 2000 44: 1900-1905. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fred C. Krebs, Shendra R. Miller, Bradley J. Catalone, Patricia A. Welsh, Daniel Malamud, Mary K. Howett, and Brian Wigdahl

Sodium Dodecyl Sulfate and C31G as Microbicidal Alternatives to Nonoxynol 9: Comparative Sensitivity of Primary Human Vaginal Keratinocytes
Antimicrob. Agents Chemother. 2000 44: 1954-1960. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl Y. Hostetler, James R. Beadle, William E. Hornbuckle, Christine A. Bellezza, Ilia A. Tochkov, Paul J. Cote, John L. Gerin, Brent E. Korba, and Bud C. Tennant

Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection
Antimicrob. Agents Chemother. 2000 44: 1964-1969. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

J. Vouillamoz, J. M. Entenza, C. Féger, M. P. Glauser, and P. Moreillon

Quinupristin-Dalfopristin Combined with -Lactams for Treatment of Experimental Endocarditis Due to Staphylococcus aureus Constitutively Resistant to Macrolide-Lincosamide-Streptogramin B Antibiotics
Antimicrob. Agents Chemother. 2000 44: 1789-1795. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Steve Kohler, L. Joseph Wheat, Patricia Connolly, Carol Schnizlein-Bick, Michelle Durkin, Melinda Smedema, Janet Goldberg, and Edward Brizendine

Comparison of the Echinocandin Caspofungin with Amphotericin B for Treatment of Histoplasmosis following Pulmonary Challenge in a Murine Model
Antimicrob. Agents Chemother. 2000 44: 1850-1854. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl V. Clemons and David A. Stevens

Efficacies of Sordarin Derivatives GM193663, GM211676, and GM237354 in a Murine Model of Systemic Coccidioidomycosis
Antimicrob. Agents Chemother. 2000 44: 1874-1877. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie Hershberger, Elizabeth A. Coyle, Glenn W. Kaatz, Marcus J. Zervos, and Michael J. Rybak

Comparison of a Rabbit Model of Bacterial Endocarditis and an In Vitro Infection Model with Simulated Endocardial Vegetations
Antimicrob. Agents Chemother. 2000 44: 1921-1924. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronda L. Akins and Michael J. Rybak

In Vitro Activities of Daptomycin, Arbekacin, Vancomycin, and Gentamicin Alone and/or in Combination against Glycopeptide Intermediate-Resistant Staphylococcus aureus in an Infection Model
Antimicrob. Agents Chemother. 2000 44: 1925-1929. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth C. Miltner and Luiz E. Bermudez

Mycobacterium avium Grown in Acanthamoeba castellanii Is Protected from the Effects of Antimicrobials
Antimicrob. Agents Chemother. 2000 44: 1990-1994. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alan M. Sugar and Xiu-Ping Liu

Combination Antifungal Therapy in Treatment of Murine Pulmonary Mucormycosis: Roles of Quinolones and Azoles
Antimicrob. Agents Chemother. 2000 44: 2004-2006. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Joseph Plouffe, Douglas B. Schwartz, Antonia Kolokathis, Bruce W. Sherman, Paul M. Arnow, John A. Gezon, Byungse Suh, Antonio Anzuetto, Richard N. Greenberg, Michael Niederman, Joseph A. Paladino, Julio A. Ramirez, Jill Inverso, Charles A. Knirsch, and the Azithromycin Intravenous Clinical Trials Group

Clinical Efficacy of Intravenous followed by Oral Azithromycin Monotherapy in Hospitalized Patients with Community-Acquired Pneumonia
Antimicrob. Agents Chemother. 2000 44: 1796-1802. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nguyen Tran Chinh, Christopher M. Parry, Nguyen Thi Ly, Huynh Duy Ha, Mai Xuan Thong, To Song Diep, John Wain, Nicholas J. White, and Jeremy J. Farrar

A Randomized Controlled Comparison of Azithromycin and Ofloxacin for Treatment of Multidrug-Resistant or Nalidixic Acid-Resistant Enteric Fever
Antimicrob. Agents Chemother. 2000 44: 1855-1859. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. L. Harousseau, A. W. Dekker, A. Stamatoullas-Bastard, A. Fassas, W. Linkesch, J. Gouveia, R. De Bock, M. Rovira, W. F. Seifert, H. Joosen, M. Peeters, and K. De Beule

Itraconazole Oral Solution for Primary Prophylaxis of Fungal Infections in Patients with Hematological Malignancy and Profound Neutropenia: a Randomized, Double-Blind, Double-Placebo, Multicenter Trial Comparing Itraconazole and Amphotericin B
Antimicrob. Agents Chemother. 2000 44: 1887-1893. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Deborah A. Mosca, Malinda A. Hurst, Wendy So, Beverly S. C. Viajar, Craig A. Fujii, and Timothy J. Falla

IB-367, a Protegrin Peptide with In Vitro and In Vivo Activities against the Microflora Associated with Oral Mucositis
Antimicrob. Agents Chemother. 2000 44: 1803-1808. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carmen Betriu, Montserrat Redondo, M. Luisa Palau, Ana Sánchez, María Gómez, Esther Culebras, Ana Boloix, and Juan J. Picazo

Comparative In Vitro Activities of Linezolid, Quinupristin-Dalfopristin, Moxifloxacin, and Trovafloxacin against Erythromycin-Susceptible and -Resistant Streptococci
Antimicrob. Agents Chemother. 2000 44: 1838-1841. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

I. Gustafsson, E. Hjelm, and O. Cars

In Vitro Pharmacodynamics of the New Ketolides HMR 3004 and HMR 3647 (Telithromycin) against Chlamydia pneumoniae
Antimicrob. Agents Chemother. 2000 44: 1846-1849. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Todd A. Davies, Lois M. Ednie, Dianne M. Hoellman, Glenn A. Pankuch, Michael R. Jacobs, and Peter C. Appelbaum

Antipneumococcal Activity of ABT-773 Compared to Those of 10 Other Agents
Antimicrob. Agents Chemother. 2000 44: 1894-1899. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alexander M. Hirschl, Petra Apfalter, Athanasios Makristathis, Manfred L. Rotter, and Margit Wimmer

In Vitro Activities of Linezolid Alone and in Combination with Amoxicillin, Clarithromycin, and Metronidazole against Helicobacter pylori
Antimicrob. Agents Chemother. 2000 44: 1977-1979. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. M. Bebear, H. Renaudin, A. Bryskier, and C. Bebear

Comparative Activities of Telithromycin (HMR 3647), Levofloxacin, and Other Antimicrobial Agents against Human Mycoplasmas
Antimicrob. Agents Chemother. 2000 44: 1980-1982. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jane D. Wong, Jason R. Barash, Rebecca F. Sandfort, and J. Michael Janda

Susceptibilities of Yersinia pestis Strains to 12 Antimicrobial Agents
Antimicrob. Agents Chemother. 2000 44: 1995-1996. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. Laclaire and R. Facklam

Antimicrobial Susceptibility and Clinical Sources of Dolosigranulum pigrum Cultures
Antimicrob. Agents Chemother. 2000 44: 2001-2003. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Wyatt C. Smith, Longkuan Xiang, and Ben Shen

Genetic Localization and Molecular Characterization of the nonS Gene Required for Macrotetrolide Biosynthesis in Streptomyces griseus DSM40695
Antimicrob. Agents Chemother. 2000 44: 1809-1817. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christopher S. Lunde and Isao Kubo

Effect of Polygodial on the Mitochondrial ATPase of Saccharomyces cerevisiae
Antimicrob. Agents Chemother. 2000 44: 1943-1953. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Martina M. Ochs, Manjeet Bains, and Robert E. W. Hancock

Role of Putative Loops 2 and 3 in Imipenem Passage through the Specific Porin OprD of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2000 44: 1983-1985. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rosane Christine Hahn and Júnia Soares Hamdan

Effects of Amphotericin B and Three Azole Derivatives on the Lipids of Yeast Cells of Paracoccidioides brasiliensis
Antimicrob. Agents Chemother. 2000 44: 1997-2000. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Kimberley A. Jackson, Sara E. Rosenbaum, Bradley M. Kerr, Yazdi K. Pithavala, Geoffrey Yuen, and Michael N. Dudley

A Population Pharmacokinetic Analysis of Nelfinavir Mesylate in Human Immunodeficiency Virus-Infected Patients Enrolled in a Phase III Clinical Trial
Antimicrob. Agents Chemother. 2000 44: 1832-1837. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael E. Klepser, Dennis Malone, Russell E. Lewis, Erika J. Ernst, and Michael A. Pfaller

Evaluation of Voriconazole Pharmacodynamics Using Time-Kill Methodology
Antimicrob. Agents Chemother. 2000 44: 1917-1920. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amy W. Peng, Stefano Milleri, and Daniel S. Stein

Direct Measurement of the Anti-Influenza Agent Zanamivir in the Respiratory Tract following Inhalation
Antimicrob. Agents Chemother. 2000 44: 1974-1976. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yupaporn Wattanagoon, Kesara Na Bangchang, Patrick G. Hoggard, Saye H. Khoo, Sara E. Gibbons, Danabhand Phiboonbhanakit, Juntra Karbwang, and David J. Back

Pharmacokinetics of Zidovudine Phosphorylation in Human Immunodeficiency Virus-Positive Thai Patients and Healthy Volunteers
Antimicrob. Agents Chemother. 2000 44: 1986-1989. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Masaki Shimizu, Fritz Shigenobu, Izumi Miyakozawa, Akio Nakamura, Kyoko Nakazawa, Masato Suzuki, Satoko Mizukoshi, Koji O'Hara, Tetsuo Sawai, and Division of Microbial Chemistry

Novel Fosfomycin Resistance of Pseudomonas aeruginosa Clinical Isolates Recovered in Japan in 1996
Antimicrob. Agents Chemother. 2000 44: 2007-2008. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.